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Dr David Fox

Associate Professor

David Fox's interests include small molecule (asymmetric) synthesis and applications of these molecules, mainly in medicinal chemistry but also materials. Nowadays ideas and projects involve synthesis as well as the calculation of molecular properties, reaction mechanism, and spectra by DFT, as well as numerical data analysis for complex catalysis kinetics.

Specialist areas include fast and direct synthesis, medicinal chemistry, and ideal scale-up methods for lead molecules.

As well as an academic role at Warwick, David Fox was a lead chemist at Functional Therapeutics (2006-12) and at Epsilon3Bio (2011-2017) and is now a consultant at RxCelerate Ltd.

d dot j dot fox at warwick dot ac dot uk

024 765 24331

Office B510

 Dr David Fox Research Group

Email me for meetings.


  • BA, Oxford
  • DPhil, Oxford
  • PDRA, Cambridge
  • Associate Professor, Warwick

Current projects include medicinal chemistry for specific enzyme inhibitors, synthetic methodology for unusual heterocycles, as well as collaborations with RxCelerate Ltd.

Synthetic organic and medicinal chemistry

  • Drug discovery and development.
  • Synthetic methodology including asymmetric and catalytic reactions, kinetics and DFT modelling.
  • Polyaromatic hydrocarbons

David Fox teaches in undergraduate modules CH222 Speclab, CH271, CH3E9, and CH408.

I am supervising the following PhD and MSc students:

  • Matthew Clayton, medicinal chemistry
  • Siana Siggers, synthetic methodology
  • Matthew Taylor, computational drug discovery
  • Harry Merrifield, medicinal chemistry

Selected Publications
  • Synthesis and characterization of triangulene
    Niko Pavliček, Anish Mistry, Zsolt Majzik, Nikolaj Moll, Gerhard Meyer, David J. Fox and Leo Gross, Nature Nanotechnology 2017, doi:10.1038/nnano.2016.305
  • Total synthesis of the azolemycins
    Zoe J. Anderson, David J. Fox Org. Biomol. Chem., 2016, DOI: 10.1039/C5OB02520f
  • Stereo- and Chemodivergent NHC-Promoted Functionalisation of Arylalkylketenes with Chloral
    J. J. Douglas, G. Churchill, A. M. Z. Slawin, D. J. Fox and A. D. Smith Chem. Eur. J., 2015, 21, 16354-16358 DOI: 10.1002/chem.201503308.
  • The Synthesis and STM/AFM Imaging of ‘Olympicene’ Benzo[cd]pyrenes
    Anish Mistry, Ben Moreton, Bruno Schuler, Fabian Mohn, Gerhard Meyer, Leo Gross, Antony Williams, Peter Scott, Giovanni Costantini and David J. Fox Chem. Eur. J. 2015, 21, 2011-2018. DOI: 10.1002/chem.201404877
  • Trichloromethyl ketones: asymmetric transfer hydrogenation and subsequent Jocic-type reactions with amines
    Perryman, Michael S.; Harris, Matthew E.; Foster, Jade L.; Joshi, Anushka; Clarkson, Guy J.; Fox, David J. Chem Commun., 2013, 49, 10022-10024. DOI:10.1039/c3cc46070c This paper was highlighted in Synfacts 2014, 10, 175. DOI:10.1055/s-0033-1340532

Further Publications