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Metals in Medicine: Books and Book Chapters

Papers
Book & Book Chapters
Patents
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Sadler Group Books & Book Chapters



Book Chapters


Cancer chemistry: designing new drugs for cancer treatment.
A.M. Pizarro, P.J. Sadler, Ch.15 pp 438-460
Biologically targeted agents from bench to beside
M. Khan, P.J.Sadler, A.M. Pizarro, S. Pelengaris. Ch.16, pp 461-508
In The Molecular Biology of Cancer. A bridge from bench to bedside. S, Pelengaris and M. Khan (eds)., 2nd ed.
Wiley-Blackwell, 2013


Metal–DNA Coordination Complexes
A.M. Pizarro, N.P.E. Barry, P.J. Sadler
In Comprehensive Inorganic Chemistry II, Vol 3. Jan Reedijk and Kenneth Poeppelmeier (eds)
Elsevier, Oxford, 2013, p. 751-784.

Interactions of Metallodrugs with DNA
H.-K. Liu, Sadler, P. J.
In NMR of Biomolecules: Towards Mechanistic Systems Biology, I. Bertini, K. McGreevy (ed.)
Wiley VCH. 2012, Chapter 16, 283-295.


Medicinal Inorganic Chemistry: State of the Art, New Trends and a Vision of the Future
N.J. Farrer and P.J. Sadler
In Bioinorganic Medicinal Chemistry, Alessio, E. (ed.)
Wiley-VCH, Weinheim, 2011, pp 1-48.


Activation Mechanisms for Organometallic Anticancer Complexes
A.M. Pizarro, A. Habtemariam and P.J. Sadler
In Medicinal Organometallic Chemistry Series: Topics in Organometallic Chemistry
Jaouen, Gérard; Metzler-Nolte, Nils (Eds.), 2010, 32, 21-56.


Di-μ-chloro(ethylbenzoate)diruthenium(II): [(η6-etb)RuCl2]2
A. Habtemariam, S. Betanzos-Lara and P.J. Sadler
Springer-Verlag, Berlin. ISBN: 978-3-642-13184-4
Inorg. Synth. 2010, 35, 160-163.


Osmium arenes: a new class of potential anticancer agents
S.H. van Rijt, A.F.A. Peacock and P.J. Sadler
In Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy Molecular Mechanisms and Clinical Applications
Humana Press Eds. A. Bonetti, R. Leone, F. M. Muggia and S. B. Howell, 2009, pp 73-79.


Metals in Medicine

P. J. Sadler, C. Muncie, and M. A. Shipman
in Biological Inorganic Chemistry, University Science Books, 2007, ISBN 1-891389-43-2
(Ivano Bertini, Harry B. Gray, Edward I. Stiefel, Joan Selverstone Valentine, Ed.)


Ruthenium arene anticancer complexes
M. Melchart and P.J. Sadler
in Bioorganometallics: Biomolecules, Labeling, Medicine.
(G. Jaouen, Ed.), Wiley_VCH Verlag GmbH & Co. KGaA: Weinheim, 2006, Ch 2, pp 39-64.


Body fluids
J.D. Bell and P.J. Sadler
in Methods in Biomedical Magnetic Resonance Imaging and Spectroscopy
(I.R. Young, Ed.), John Wiley & Sons, 2000


Application of ICP-MS to the investigation of chemical reactions of candidate metallodrugs with biomolecules
M. Patriarca, N.A. Kratochwil and P.J. Sadler
in Plasma Source Mass Spectrometry,
(G. Holland and S.C. Tanner, Eds.) Roy. Soc. Chem., Cambridge, 1999, pp199-207.


195Pt and 15N NMR spectroscopic studies of cisplatin reactions with biomolecules
Y. Chen, Z. Guo and P.J. Sadler
in Cisplatin - chemistry and biochemistry of a leading anticancer drug
(B. Lippert Ed.) Verlag Helvetica Chimica Acta, Zürich, 1999, 293-318.


NMR Spectroscopy of platinum drugs: from DNA to body fluids
K.J. Barnham, S.J. Berners-Price, Z. Guo, P. del S. Murdoch and P.J. Sadler
in Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy, 2,
(H.M. Pinedo and J.H. Schornagel, Eds.), Plenum Press, New York, 1996, 1-16.


Body fluid spectroscopic studies
J.D. Bell and P.J. Sadler
in Encyclopedia of Nuclear Magnetic Resonance,
(D.M. Grant and R.K. Harris, Eds.), J. Wiley & Sons, Chicester, 1996, vol 2, pp 989-1001.


Gold drugs
P.J. Sadler and R.E. Sue
in Handbook of Metal-Ligand Interactions in Biological Fluids, Bioinorganic Chemistry, vol. 2
(G. Berthon, Ed.), Marcel Dekker Inc, New Yjamesork, 1995, pp 1039-1051.


Ga3+-induced structural changes in human serum transferrin: [1H, 13C] NMR studies of methionine residues in the N-lobe
E.J. Beatty, M.C. Cox, T.A. Frenkiel, G. Kubal, A.B. Mason, P.J. Sadler and R.C. Woodworth
in Metal Ions in Biology and Medicine,
(Ph. Collery, N.A. Littlefield, J.C. Etienne Eds.) John Libby Eurotext, Paris, 1994, 315-320.


Multi-metal binding site on serum albumin
W. Bal, J. Christodoulou, P.J. Sadler and A. Tucker
in Metal Ions in Biology and Medicine,
(Ph. Collery, N.A. Littlefield, J.C. Etienne Eds.) John Libby Eurotext, Paris, 1994, 43-45.


Gold complexes in cancer chemotherapy
O.M. Ni Dhubhghaill and P.J. Sadler
in Metal Complexes in Cancer Chemotherapy,
(B.K. Keppler, Ed.), VCH Publ., Weinheim, 1993, pp221-248.


Metallodrugs: the role of thiolate proteins and metal-thiolate complexes in metal binding
M. D. Rhodes, J. D. Ranford and P. J. Sadler
in Metallothioneins : Synthesis, Structure and Properties of Metallothioneins, Phytochelatins and Metal-thiolate Complexes,
(M.J. Stillman, C.F. Shaw III and K.T. Suzuki, eds.) VCH Publishers, 1992, Ch. 16, pp 408 - 435.


Inorganic drugs: a periodic table of pharmaceutical and diagnostic agents
P.J. Sadler
in Lectures in Bioinorganic Chemistry,
(M. Nicolini and L. Sindellari, Eds.) Cortina Int./Raven, Verona/NY, 1991, 1-24.


Labels and contrast agents in biomedical magnetic resonance spectroscopy and imaging
S.W.A. Bligh and P.J. Sadler
in Clinical NMR Spectroscopy,
(J. Dykes and D.T. Delpy, Eds.) Report No. 60 of the Institute of Physical Sciences in Medicine, Pubs.
European Organisations of Medical Physics and Institute of Physical Sciences in Medicine, 1989, 71-82.


NMR Studies of metallodrugs
P.J. Sadler
in NMR Spectroscopy in Drug Research,
( J.W. Jaroszewski, K. Schaumburg and H. Kofod, Eds.) Alfred Benzon Symposium 26, Munksgaard, Copenhagen 1988, 252-268.


The anticancer activity of metal phosphine complexes
S.J .Berners Price and P.J. Sadler
in Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy
(M. Nicolini, Ed.) Martinus Nijhoff Pub. 1988, 527-537


Proton NMR studies of urine
P.J. Sadler
in Biochemical mechanisms of platinum antitumour drugs,
(D.C.H. McBrien and T.R. Slater, Eds.) IRL Press Ltd., Oxford, 1986, 383-392.


The environmental chemistry of metals with examples from the speciation of cadmium
P.J. Sadler, D.P. Higham and J.K. Nicholson
in Environmental Inorganic Chemistry,
(K.J. Irgolic and A.E. Martell, Eds.) Proceedings, US-Italy International Workshop on Environmental Inorganic Chemistry, San Miniato, Italy, June 5-10, 1983,
VCH Publishers, Inc., Deerfield Beach, Florida, USA 1985, 249-72.


195Pt NMR Spectroscopy: applications to the study of anticancer drugs
F.M. Macdonald and P.J. Sadler
in Biochemical mechanisms of platinum antitumour drugs,
(D.C.H. McBrien and T.R. Slater, Eds.) IRL Press Ltd., Oxford, 1986, 361-381.


Gold drugs
S.J. Berners Price and P.J. Sadler
in Bioinorganic Chemistry,
(A.V. Xavier, Ed.), VCH Publishers, 1985, 376-388.

NMR and EXAFS Studies of metallodrugs and metalloproteins
S.J. Berners Price, I.M. Ismail, M.A.Mazid, M.T. Razi, P.J. Sadler and G.N. Greaves
in Biological Systems : Structure and Analysis,
Daresbury Laboratory 24-25 March 1984, SERC Report DL/SCI/R22, 1984, 18-27


The design of metal complexes as anticancer drugs
P.J. Sadler, M. Nasr and V.L. Naranayan
in Platinum Coordination Complexes in Cancer Chemotherapy,
(M.P. Hacker, E.B. Douple and I.H. Krakhoff, Eds.) Martinus Nijhoff, Boston, Mass., 1984, 290-304.


Books


Metallopharmaceuticals-I: DNA Interactions

Topics in Biological Inorganic Chemistry, vol. 1
Eds: M. J. Clarke, P. J. Sadler
Springer Verlag, Berlin, 1999

Metal Sites in Proteins and Models: Iron Centres

Eds: H.A.O. Hill, A.J. Thomson and P.J. Sadler
Structure & Bonding, vol 88
Springer Verlag, Berlin, 1997


Metal Sites in Proteins and Models: Phosphatases, Lewis Acids and Vanadium

Eds: H.A.O. Hill, A.J. Thomson and P.J. Sadler
Structure & Bonding, vol 89
Springer Verlag, Berlin, 1997


Metal Sites in Proteins and Models: Redox Centres

Eds: H.A.O. Hill, A.J. Thomson and P.J. Sadler
Structure & Bonding, vol 90
Springer Verlag, Berlin, 1997


The Importance of Chemical “Speciation” in Environmental Processes

Dahlem Konferenzen Life Sciences Research Report 33
Eds: M. Bernhard, F.E. Brinckman and P.J. Sadler,
Springer Verlag, Berlin, 1986