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Metals in Medicine: Patents

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Patents

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Sadler Group Patents

 

Preparation and antitumor activity of organometallic osmium compounds.
Sadler, Peter John; Peacock, Anna Frances Acushla; Van Rijt, Sabine Helena; Habtemariam, Abraha.

PCT Int. Appl. (2008), 91pp. CODEN: PIXXD2 WO 2008017855 A1 20080214


Preparation of organometallic ruthenium(II) compounds and their cytotoxic activity. 
Habtemariam, Abraha; Bugarcic, Tijana; Sadler, Peter John.

PCT Int. Appl. (2007), 46pp. CODEN: PIXXD2 WO 2007135410 A1 20071129


Preparation of half-sandwich ruthenium(II) compounds and their use in cancer therapy.
Dougan, Sarah; Habtemariam, Abraha; Melchart, Michael; Sadler, Peter.

PCT Int. Appl. (2007), 61pp. CODEN: PIXXD2 WO 2007101997 A1 20070913


Preparation of water-soluble platinum(IV) azido complexes and compositions for photoactivation in treatment of tumors.
Sadler, Peter John; Muller, Philippe.

U.S. Pat. Appl. Publ. (2007), 14pp., Cont.-in-part of U.S. Ser. No. 487,758. CODEN: USXXCO US 2007142466 A1 20070621


Preparation of water-soluble platinum(IV) azido complexes and compositions for photoactivation in treatment of tumors.
Sadler, Peter John; Muller, Philippe

U.S. Pat. Appl. Publ. (2007), 14pp., Cont.-in-part of U.S. Ser. No. 487,758. CODEN: USXXCO US 2007142466 A1 20070621 CAN 147:85545 AN 2007:672962


Arene ruthenium(II) compounds and their use in cancer therapy.
Habtemariam, Abraha; Sadler, Peter John

PCT Int. Appl. (2006), 45 pp. CODEN: PIXXD2 WO 2006018649 A1 20060223 CAN 144:233199 AN 2006:164382


Preparation of ruthenium(II) complexes for the treatment of tumors.
Habtemariam, Abraha; Sadler, Peter John

PCT Int. Appl. (2004), 38 pp. CODEN: PIXXD2 WO 2004096819 A1 20041111 CAN 141:395672 AN 2004:965262


Design of mutated forms of human serum albumin with altered metal binding characteristics for pharmacological or cell culture uses.
Berezenko, Stephen; Sadler, Peter John; Stewart, Alan James; Blindauer, Claudia

PCT Int. Appl. (2004), 63 pp. CODEN: PIXXD2 WO 2004011499 A1 20040205 CAN 140:177081 AN 2004:101193


Preparation of half-sandwich ruthenium anticancer complexes.
Sadler, Peter John; Fernandez Lainez, Rafael; Habtemariam, Abraba; Melchart, Michael; Jodrell, Duncan Ian

PCT Int. Appl. (2004), 46 pp. CODEN: PIXXD2 WO 2004005304 A1 20040115 CAN 140:94145 AN 2004:41485


Photoreactive compounds and compositions
Sadler, Peter John; Mueller, Philippe

PCT Int. Appl. (2003), 32 pp. CODEN: PIXXD2 WO 2003017993 A1 20030306 CAN 138:215273 AN 2003:173413


Half-sandwich ruthenium(II) compounds comprising heteroatom containing ligands for treatment of cancer.
Morris, Robert Edward; Sadler, Peter John; Jodrell, Duncan; Chen, Haimei

PCT Int. Appl. (2002), 32 pp. CODEN: PIXXD2 WO 2002002572 A1 20020110 CAN 136:85944 AN 2002:31461


Half-sandwich ruthenium(II) compounds comprising nitrogen containing ligands for treatment of cancer.
Morris, Robert Edward; Sadler, Peter John; Chen, Haimei; Jodrell, Duncan

PCT Int. Appl. (2001), 36 pp. CODEN: PIXXD2 WO 2001030790 A1 20010503 CAN 134:326632 AN 2001:319903


Detection of albumin in physiological fluids.
Sadler, Peter John; Viles, John Howard; Tucker, Alan; Patel, Sunil Unka

PCT Int. Appl. (1994), 23 pp. CODEN: PIXXD2 WO 9420863 A1 19940915 CAN 121:276177 AN 1994:676177


Contrast agents for NMR imaging of the gastrointestinal tract containing paramagnetic metal ion complexes with amino phosphonates.
Sadler, Peter John; McEwen, Andrew Bruce

Eur. Pat. Appl. (1988), 21 pp. CODEN: EPXXDW EP 275215 A1 19880720 CAN 111:74025 AN 1989:474025


Contrast agents for NMR spectroscopy and their use.
Sadler, Peter John; McEwen, Andrew Bruce

Eur. Pat. Appl. (1988), 9 pp. CODEN: EPXXDW EP 276058 A1 19880727 CAN 111:36264 AN 1989:436264


Amino phosphonate-cation complexes as contrast agents for NMR scanning of calcified tissues.
Sadler, Peter John; Harding, Charles Thomas; Kelly, James Duncan; McEwen, Andrew Bruce

Eur. Pat. Appl. (1987), 20 pp. CODEN: EPXXDW EP 210043 A2 19870128 CAN 108:128096 AN 1988:128096


Nitroxyl spin-labeled polysaccharides and their complexes with paramagnetic metal ions as NMR diagnostic and imaging agents.
Sadler, Peter John; Harding, Charles Thomas

PCT Int. Appl. (1987), 21 pp. CODEN: PIXXD2 WO 8701594 A1 19870326 CAN 107:112219 AN 1987:512219


NMR contrast agents.
Sadler, Peter John; Harding, Charles Thomas

PCT Int. Appl. (1985), 22 pp. CODEN: PIXXD2 WO 8505554 A1 19851219 CAN 105:111479 AN 1986:511479


Tumor cell growth-inhibiting pharmaceutical compositions containing phosphino-hydrocarbon-gold, silver or copper complexes.
Berners-Price, Susan Jane; Mirabelli, Christopher Kevin; Johnson, Randall Keith; Sadler, Peter John

Eur. Pat. Appl. (1985), 37 pp. CODEN: EPXXDW EP 164970 A2 19851218 CAN 105:12101 AN 1986:412101


Metal complexes of nitro-substituted pyrazoles, imidazoles and isothiazoles.
Gilmour, David Wilkinson; Sadler, Peter John

Brit. UK Pat. Appl. (1984), 14 pp. CODEN: BAXXDU GB 2122194 A 19840111 CAN 100:203599 AN 1984:203599


Platinum nitroimidazole complexes and pharmaceutical compositions containing them.
Coulson, Christopher James; Sadler, Peter John

Fr. Demande (1982), 31 pp. CODEN: FRXXBL FR 2500449 A1 19820827 CAN 98:91949 AN 1983:91949