Papers

Book & Book Chapters

Patents

Open Access

Full list of all open access publications can be found by clicking here.

Most Recent Open Access Publications;

Ferric ion hydr(oxo) clusters in the ‘Venus-Fly-Trap’ cleft of FbpA: Mössbauer, calorimetric and mass spectrometric studies A. Mukherjee, P.R. Bilton, L. Mackay, A. Janoschka, H. Zhu, D. Rea, P.R.R. Langridge-Smith, Dominic J. Campopiano, Thomas Teschner, Alfred X. Trautwein, Volker Schünemann, Peter J. Sadler J. Biol. Inorg. Chem. 2012, 17, 573-588.

Photoactivatable Organometallic Pyridyl Ruthenium(II) Arene Complexes S. Betanzos-Lara, L. Salassa, A. Habtemariam, O. Nováková, A.M. Pizarro, G.J. Clarkson, B. Liskova, V. Brabec, P.J. Sadler Organometallics 2012, 31, 3466–3479.

Dicarba-closo-dodecarborane-containing half-sandwich complexes of ruthenium, osmium, rhodium and iridium: biological relevance and synthetic strategies N.P.E. Barry, P.J. Sadler Chem. Soc. Rev. 2012, 41, 3264–3279

Interactions of DNA with a New Platinum(IV) Azide Dipyridine Complex Activated by UVA and Visible Light. Relationship to Toxicity in Tumor Cells J. Pracharova, L. Zerzankova, J. Stepankova, O. Novakova, N.J. Farrer, P.J. Sadler, V. Brabec, J. Kasparkova Chem. Res. Toxicol. 2012, 25, 1099-1111.

Designing organometallic compounds for catalysis and therapy A.L. Noffke, A. Habtemariam, A.M. Pizarro, P.J. Sadler Chem. Commun. 2012, 48, 5219-5246.

Combined theoretical and computational study of interstrand DNA guanine-guanine cross-linking by trans-[Pt(pyridine)2] derived from the photoactivated prodrug trans,trans,trans-[Pt(N3)2(OH)2(pyridine)2] H.-C, Tai, R. Brodbeck, J. Kasparkova, N.J. Farrer, V. Brabec, P.J.Sadler, R.J. Deeth Inorg. Chem. 2012, 51, 6830-6841.

The contrasting Chemical Reactivity of Potent Isoelectronic Iminopyridine and Azopyridine Osmium(II) Arene Anticancer Complexes Y. Fu, M.J. Romero, A. Habtemariam, M.E. Snowden, L. Song, G.J. Clarkson, B. Qamar, A.M. Pizarro, P.R. Unwin, P.J. Sadler Chem. Sci. 2012, 3, 2485–2494.

Microfluidic integration of photonic crystal fibers for online photochemical reaction analysis S. Unterkofler, R. McQuitty, T. Euser, N. Farrer, P.J. Sadler, P. Russell Optics Lett. 2012, 37, 1952-1954.

Bipyrimidine Ruthenium(II) Arene Complexes: Structure, Reactivity and Cytotoxicity S. Betanzos-Lara, O. Novakova, R.J. Deeth, A.M. Pizarro, G.J. Clarkson, Barbora Liskova, V. Brabec, P.J. Sadler, A. Habtemariam J. Biol. Inorg. Chem. 2012, 17, 1033-1051.

Design of Photoactivatable Metallodrugs: Selective and Rapid Light-induced Ligand Dissociation from Half-Sandwich [Ru([9]aneS3)(N–N')(py)]2+ Complexes G. Ragazzon, I. Bratsos, E. Alessio, L. Salassa, A. Habtemariam, R.J. McQuitty, G.J. Clarkson, P.J. Sadler Inorg. Chim. Acta 2012, 393, 230-238. (Bioinorganic Special Issue)

Allosteric Inhibition of Cobalt Binding to Albumin by Fatty Acids: Implications for the Detection of Myocardial Ischemia J. Lu, A.J. Stewart, P.J. Sadler, T.J.T. Pinheiro, C.A. Blindauer J. Med. Chem. 2012, 55, 4425-4430.

Improved Catalytic Activity of Ruthenium-Arene Complexes in the Reduction of NAD+ J.J. Soldevila-Barreda, P.C.A. Bruijnincx, A. Habtemariam, G.J. Clarkson, R.J. Deeth, P.J. Sadler Organometallics 2012, 31, 5958-5967.

Resonant X-Ray Emission Spectroscopy Reveals d–d Ligand-Field States Involved in the Self-Assembly of a Square-Planar Platinum Complex C. Garino, E. Gallo, N. Smolentsev, P. Glatzel, R. Gobetto, C. Lamberti, P.J. Sadler, L. Salassa Phys. Chem. Chem. Phys. 2012, 15278-15281.

Somatostatin subtype 2 receptor-targeted metal-based anticancer complexes F. Barragán, D. Carrion-Salip, I. Gómez-Pinto, A. González-Cantó, P.J. Sadler, R. de Llorens, V. Moreno, C. González, A. Massaguer, V. Marchán Bioconjugate Chem. 2012, 23, 1838-1855.

Tryptophan Switch for a Photoactivated Platinum Anticancer Complex J.S. Butler, J.A. Woods, N.J Farrer, M.E. Newton, P.J. Sadler J. Am. Chem. Soc. 2012, 134, 16508-16511.

Contrasting cellular uptake pathways for chlorido and iodido iminopyridine ruthenium arene anticancer complexes I. Romero-Canelón, A.M. Pizarro, A. Habtemariam, P.J. Sadler Metallomics 2012, 4, 1271-1279.

Reduction of Quinones by NADH Catalyzed by Organoiridium Complexes. Liu, Z.; Deeth, R. J.; Butler, J. S.; Habtemariam, A.; Newton, M. E.; Sadler, P. J. Angew. Chem., Int. Ed. 2013, 52, 4194-4197.

Photoactivatable metal complexes: from theory to applications in biotechnology and medicine Nichola A. Smith and Peter J. Sadler. Phil. Trans. R. Soc. A. 2013, DOI: 10.1098/rsta.2012.0519