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Papers 2014

Sadler Papers 2014

- Mechanism of cellular accumulation of an iridium(III) pentamethylcyclopentadienyl anticancer complex containing a C,N-chelating ligand

V. Novohradsky, Z. Liu, P.J. Sadler, V. Brabec, J. Kasparkova

Metallomics 2014, 6, 682-690.

- The potent oxidant anticancer activity of organoiridium catalysts

Z. Liu, I. Romero-Canelón, B. Qamar, J.M. Hearn, A. Habtemariam, N.P.E. Barry, A.M. Pizarro, G.J. Clarkson, P.J. Sadler

Angew. Chem. Int. Ed. 2014, 53, 3941–3946.

(Very Important Paper)

- Organoiridium Complexes: Anticancer Agents and Catalysts

Z. Liu, P.J. Sadler

Acc. Chem. Res. 2014, 47,1174-85.

- Insights into the Binding Sites of Organometallic Ruthenium Anticancer Compounds on Peptides Using Ultra-High Resolution Mass Spectrometry

R.H. Wills, A. Habtemariam, A.F. Lopez-Clavijo, M.P. Barrow, P.J. Sadler, P.B. O’Connor

J. Am. Soc. Mass Spectrom. 2014, 25, 662-672.

- A multinuclear 1H, 13C and 11B solid-state MAS NMR study of 16- and 18-electron organometallic ruthenium and osmium carborane complexes

N.P.E. Barry, T.F. Kemp, P.J. Sadler, J.V. Hanna

Dalton Trans. 2014, 43, 4945–4949.

- Potent organometallic osmium compounds induce mitochondria-mediated apoptosis and S-phase cell cycle arrest in A549 non-small cell lung cancer cells

S.H. van Rijt, I. Romero-Canelón, Y. Fu, S.D. Shnyder, P.J. Sadler

Metalllomics 2014, 6, 1014-1022.

(Hot Article)

-Fabrication of crystals from single metal atoms

N.P.E. Barry, A. Pitto-Barry, A.M. Sanchez, A.P. Dove, R.J. Procter, J.J. Soldevila-Barreda, N. Kirby, I. Hands-Portman, C.J. Smith, R.K. O’Reilly, R. Beanland, P.J. Sadler

Nature Commun. 2014, 5:3851 | DOI: 10.1038/ncomms4851

- A dual-targeting, apoptosis-inducing organometallic half-sandwich iridium anticancer complex

V. Novohradsky, L. Zerzankova, J. Stepankova, A. Kisova, Z. Liu, J. Kasparkova, P.J. Sadler, Viktor Brabec

Metallomics 2014, 6, 1491-1501

- Cellular Accumulation, Lipophilicity and Photocytotoxicity of Diazido Platinum(IV) Anticancer Complexes

A.M. Pizarro, R.J. McQuitty, F.S. Mackay, Y. Zhao, J.A. Woods, P.J. Sadler

ChemMedChem 2014, 9, 1169-1175.

- Precious metal carborane polymer nanoparticles: characterisation of micellar formulations and anticancer activity

N.P.E. Barry, A. Pitto-Barry, I. Romero-Canelón, J. Tran, J.J. Soldevila-Barreda, I. Hands-Portman, C.J. Smith, N. Kirby, A. Dove, R.K. O’Reilly, P.J. Sadler

Faraday Discussions 2014, in press

- Ultrafast Photo-Induced Ligand Solvolysis of cis-[Ru(bipyridine)2(nicotinamide)2]2+: Experimental and Theoretical Insight into its Photoactivation Mechanism

S.E. Greenough, G.M. Roberts, N.A. Smith, M.D. Horbury, R.G. Mckinlay, J.M. Żurek, M.J. Paterson, P.J. Sadler, V.G. Stavros

Phys. Chem. Chem. Phys. 2014, 16, 19141-19155.

- [Fe(CN)5(isoniazid)]3- : an Iron Isoniazid Complex with Redox Behavior Implicated in Tuberculosis Therapy

E.H. Silva Sousa, F. Gilmara de Mesquita Vieira, J.S. Butler, L. Augusto Basso, D.S. Santiago, Izaura C.N. Diógenes, L. Gonzaga de França Lopes, P.J. Sadler

J. Inorg. Biochem. 2014, 140, 236–244

- 100 Years of Metal Coordination Chemistry: from Alfred Werner to Anticancer Metallodrugs

N.P.E. Barry, P.J. Sadler

Pure & Applied Chem. 2014, 86, 1897–1910.

44th IUPAC World Chemistry Congress

- Potent Half-Sandwich Iridium(III) Anticancer Complexes Containing C^N-Chelated and Pyridine Ligands

Z. Liu, I. Romero-Canelón, A. Habtemariam, G.J. Clarkson, P.J. Sadler

Organometallics 2014, 33, 5324–5333.

- Platinum(II)-Gadolinium(III) Complexes as Potential Single Molecular Theranostic Agents for Cancer Treatment

Z. Zhu, X. Wang, T. Li, S. Aime, P.J. Sadler, Z. Guo

Angew. Chem. Int. Ed. 2014, 53, 13225-13228.

- Formation of glutathione sulfenate and sulfinate complexes by an organoiridium(III) anticancer complex

Z. Liu, P.J. Sadler

Inorg. Chem. Front. 2014, 1, 668-672.

- Mass Spectrometric Strategies to Improve the Identification of Pt(II)-Modification Sites on Peptides and Proteins

H. Li, Huilin, J.R. Snelling, M.P. Barrow, P.J.Sadler, P. O‘Connor

J. Amer. Soc. Mass Spec. 2014, 25. 1217-1227.