David Fox -old

Associate Professor

David Fox's interests include small molecule (asymmetric) synthesis and applications of these molecules, mainly in medicinal chemistry / drug discovery and scale-up and GMP process development. Specialist areas include drug molecule design, fast and direct synthesis, and synthetic route development for lead molecules.

As well as an academic role at Warwick, David Fox was a lead chemist at Functional Therapeutics (2006-12) and at Epsilon3Bio (2011-2017) and is now a consultant at RxCelerate Ltd.

d dot j dot fox at warwick dot ac dot uk

024 765 24331

Office B510

Dr David Fox Research Group

Email me for meetings.

Biography

BA, Oxford
DPhil, Oxford
PDRA, Cambridge
Associate Professor, Warwick

Current projects include medicinal chemistry for specific enzyme inhibitors, synthetic methodology for unusual heterocycles, as well as collaborations with RxCelerate Ltd.

Synthetic organic and medicinal chemistry

Drug discovery and development.
Synthetic methodology including asymmetric and catalytic reactions.
Scale-up route design

David Fox teaches in undergraduate modules CH222 Speclab, CH271, CH3E9, and CH408.

I am supervising the following PhD and MSc students:

Matthew Clayton, medicinal chemistry
Matthew Taylor, computational drug discovery
Emma Scott, synthetic methodology

Selected Publications

Synthesis and characterization of triangulene

Niko Pavliček, Anish Mistry, Zsolt Majzik, Nikolaj Moll, Gerhard Meyer, David J. Fox and Leo Gross, Nature Nanotechnology 2017, doi:10.1038/nnano.2016.305
Total synthesis of the azolemycins

Zoe J. Anderson, David J. Fox Org. Biomol. Chem., 2016, DOI: 10.1039/C5OB02520f
Stereo- and Chemodivergent NHC-Promoted Functionalisation of Arylalkylketenes with Chloral

J. J. Douglas, G. Churchill, A. M. Z. Slawin, D. J. Fox and A. D. Smith Chem. Eur. J., 2015, 21, 16354-16358 DOI: 10.1002/chem.201503308.
The Synthesis and STM/AFM Imaging of ‘Olympicene’ Benzo[cd]pyrenes

Anish Mistry, Ben Moreton, Bruno Schuler, Fabian Mohn, Gerhard Meyer, Leo Gross, Antony Williams, Peter Scott, Giovanni Costantini and David J. Fox Chem. Eur. J. 2015, 21, 2011-2018. DOI: 10.1002/chem.201404877
Trichloromethyl ketones: asymmetric transfer hydrogenation and subsequent Jocic-type reactions with amines

Perryman, Michael S.; Harris, Matthew E.; Foster, Jade L.; Joshi, Anushka; Clarkson, Guy J.; Fox, David J. Chem Commun., 2013, 49, 10022-10024. DOI:10.1039/c3cc46070c This paper was highlighted in Synfacts 2014, 10, 175. DOI:10.1055/s-0033-1340532

Further Publications