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Past Studies

The following Portfolio studies are closed to recruitment. For more information on each study please use the link. Some studies that are closed to recruitment continue the follow up of patients for several years. Once the results of these studies are known they will be published under the Results of Completed Studies on the Portfolio Studies’ home page.

For further information on any study mentioned below, please contact Sue Elwell,

Study Name Short Description
FACE TIA Functional, Cognitive, Emotional Outcome after Transient Ischaemic Attack
ESTEEM 1 The Effectiveness & Cost-Effectiveness of Telephone Triage of Patients Requesting Same Day Consultations in General Practice
Understanding Social Contributions to the Disparities in Depression Care: US & UK Understanding Social Contributions to the Disparities in Depression Care: US & UK
ASCEND A Study of Cardiovascular Events In Diabetes
CCHi The Evaluation of The Health Foundation’s Co-Creating Health Initiative
DeMist Dietetic Management in Smokers Trial
Lung Search A Randomised Control Trial for the Surveillance for the Early Detection of Lung Cancer in an At Risk Group
PAST BP A Randomised Controlled Trial of Different Blood Pressure Targets for People with a History of Stroke or Transient Ischaemic Attack in Primary Care
Piloting QOF-NICE Indicators Piloting Quality & Outcomes Framework-National Institute for Health & Clinical Excellence Indicators: Recruiting Practices & Field Work within Practices
3Cs Cough Complication Cohort Study


A Primary Care Trial of a Website Based Infection Control Intervention to Modify Influenza-like illness & Respiratory Infection Transmission


Standard Care versus Celecoxib Outcome Trial

Medicated Sleep & Wakefulness

Medicated Sleep & Wakefulness: A Social Scientific Study of Stakeholder Interest, Policies & Practices



Implementing the GRIST Clinical Decision Support System within Primary Care & the Community, to Improve Detection & Management of Suicide Risk amongst Depressed Patients



Weight Loss Referrals for Adults in Primary Care


Slimming World in Stop Smoking Services


A randomised trial to increase the uptake of smoking cessation services using personal targeted risk information and Taster Sessions


AUtomated Risk Assessment for Stroke in Atrial Fibrillation


Birmingham Atrial Fibrillation Treatment of the Aged Follow-up


Positive Online Weight Reduction


Polymyalgia Rheumatica Study


The early use of Antibiotics in at Risk Children with InfluEnza


Early Venous Reflux Ablation Ulcer Trial

Fruit Bioactives

Fruit Bioactives for Good Metabolic and Vascular Health


Prevention of Fall Injury Trial


Vitamin D and Longevity


Focus group for patients receiving a negative FObT result


Families for Health


Polycystic Ovary Syndrome


Brief Interventions for Weight Loss


Healthy Living for People with Diabetes


Patient self-management in primary care patients with COPD - a randomised controlled trial


Dementia and Physical Activity


An Open Label Pragmatic Randomised Controlled Trial of Nicotine Preloading for Smoking Cessation


Electronically delivered, multi-component intervention to reduce unnecessary antibiotic prescribing in primary care. Cluster randomised trial using electronic health records

Survey of English GPs access to diagnostic tests for cancer

An online survey of General Practitioners about access to diagnostic tests to investigate for cancer across NHS England.


Extended Anticoagulation Treatment for VTE

FAST - four-fold asthma

Examining the clinical and cost effectiveness of temporarily quadrupling the dose of inhaled steroid to prevent asthma exacerbations: a pragmatic, randomised, normal care-controlled, clinical trial.


Managing cardiovascular risk for people with mental health problems


Telemonitoring and/or self-monitoring of blood pressure in hypertension: A randomised controlled trial in primary care

STARR STudying Acute exaceRbations and Responses: COPD

Qualitative study exploring GP experience of managing glue ear

LASER Laminar Airflow in Severe Asthma for Exacerbation Reduction
EMiNA Evaluation of Migrant Women’s Needs regarding Domestic Violence and Abuse
DARE Diabetes Alliance for Research in England
OSAC Oral Steroids for Acute Cough
ARCH A Study to Determine the Efficacy and Safety of AMG 785 in the Treatment of Postmenopausal Women With Osteoporosis
FADES A national cohort of infants with Down's syndrome to study associations between early feeding, infections and development of auto-immunity

GCA (Giant Cell Arteritis)

TIME Treatment in Morning versus Evening
TOSCA Trial of Sertraline versus CBT for generalised Anxiety
MDD Major Depressive Disorder
FFH - Families for Health A randomised controlled trial evaluating the effectiveness and cost-effectiveness of 'Families for Health’ a family based childhood obesity treatment intervention delivered in a community setting for ages 6-11 years
TWICS Theophylline with inhaled corticosteroids
PRiDE Micronutrients in Pregnancy Study
DCS: Discharge Summaries To determine the rate at which error occurs when processing discharge summaries
All Heart Allopurinol &cardiovascular outcomes in patients with ischaemic heart disease
CANcer DIagnosis Decision rules
A major multicentre clinical trial evaluating long term cardiovascular safety of febuxostat in comparison with
allopurinol in patients with chronic symptomatic hyperuricaemia
A study looking at genetic factors and their role in thinness
HEAT Helicobacter Eradication Aspirin Trial
Home-BP Home and online management and evaluation of blood pressure
Testing patients' blood pressure monitors
Primary Care use of a C-Reactive Protein (CRP) Point of Care Test (POCT) to help target antibiotic prescribing to patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) who are most likely to benefit
REACT (Relatives Education And Coping Toolkit) online peer-supported toolkit for relatives of people with psychosis or bipolar disorder