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The Mechanobiology of Shape: from Molecules to Tissues

About the event

This meeting is motivated by shared research interests between the Centre for Mechanochemical Cell Biology at Warwick and the Laboratory for Molecular Cell Biology at UCL. However, the meeting is open to other interested researchers, especially ECRs.

Organisers: Associate Prof Timothy Saunders (Warwick) and Prof Yanlan Mao (UCL)

Location: Interdisciplinary Biomedical Research Building (IBRB) Gibbet Hill Campus, University of Warwick

Forming specific cellular and tissue shapes is a multi-scale process. Processes from the molecular scale through to tissue scale are critical in ensuring robust morphogenesis. Further, it is becoming increasingly apparent that understanding when processes occur is critical in generating specific biological shape. This also makes the importance of integrating modelling clear; biophysical and mathematical modelling provides a powerful framework for understanding how processes occurring across multiple scales can impact on morphogenesis.

This meeting will have plenty of time provided for questions and interactions between researchers working at different levels of detail and with differing approaches.

Key questions include:

  • How do subcellular scale processes shape cells and tissues?
  • Different molecular processes occur across a broad range of time scales. What role does temporal coordination play in precise organ formation?
  • Is there feedback from tissue scale processes back to subcellular levels – e.g., in gene regulation? Such mechanotransduction could be important in robust organogenesis.

Event schedule 

Thursday 4 May

Location: Interdisciplinary Biomedical Research Building (IBRB)

Programme:

9.00am - Arrival and registration

10.00am - Session 1 – mechanobiology of shape at the subcellular scale

12.30pm - Lunch and roundtable discussions

2.00pm - Session 2: mechanobiology of shape at the cellular scale

4.30pm - Roundtable discussions

6.00pm - Dinner and further discussion


Friday 5th May 2023

Location: Interdisciplinary Biomedical Research Building (IBRB)

Programme:

9.30am - Session 3: mechanobiology of shape at the tissue scale

12.00pm - Lunch and Roundtable discussions

1.30pm - Session 4: modelling mechanics within biological systems

4.00pm - Final remarks and discussion


5pm - Departure

Event Information:

Date: 4 | 5 May 2023

Venue - IBRB Warwick

Please click here for Accommodation information

How to find us

Funding support:

We are grateful for support from PoLNET3 and the Warwick Institute of Advanced Studies.

Provisional Groups Attending: 

Mohan Balasubramanian (Warwick)

Guillaume Charras (UCL)

Robert Cross (Warwick)

Mohit Dalwadi (UCL)

Nate Goehring (UCL)

Zena Hadjivasiliou (UCL)

Bart Hoogenboom (UCL)

Darius Köster (Warwick)

Yanlan Mao (UCL)

Roberto Mayor (UCL)

Andrew McAinsh (Warwick)

Andrew Miller (Warwick)

Masanori Mishima (Warwick)

Philip Pearce (UCL)

Franck Pichaud (UCL)

Aparna Ratheesh (Warwick)

Steve Royle (Warwick)

Karuna Sampath (Warwick)

Timothy Saunders (Warwick)

Michael Smutny (Warwick)

Anne Straube (Warwick)

Matthew Turner (Warwick)

Mie Wong (UCL)