Biomedical Sciences
Inspired minds, inspired places
The Division of Biomedical Sciences has a vision to build world-class Discovery Science and Translational Medicine programmes in partnership with the University Hospital Coventry & Warwickshire (UHCW), deliver interdisciplinary educational programmes and transmit new knowledge to the wider world through an exciting public engagement interface. The divison is home to 41 Principal Investigators including both clinical and non-clinical academics, several jointly appointed with other departments to drive interdisciplinary work.
Leading edge research centres and programmes
Our Principal Investigators lead key University-wide research centres, externally supported research programmes and innovative education initiatives:
Events and seminars
BMS Seminar: Dr Ying Chow, Assistant Professor, Department of Physics, University of Warwick
BMS Seminar: Dr Timothy Saunders, Associate Professor in Human Disease Biology, Division of Biomedical Sciences, Warwick Medical School, University of Warwick
BMS Seminar: Rethinking the neural crest – Cyclical Fate Restriction, Professor Robert Kelsh, Department of Biology and Biochemistry, University of Bath
Biomedical Sciences News
Cell-Type-Specific Circadian Bioluminescence Rhythms in Dbp Reporter Mice
In collaboration with groups at UMass Med School, Smith College and Morehouse University, we have developed a reporter mouse generated by modification of a widely expressed and highly rhythmic gene encoding D-site albumin promoter binding protein (Dbp). In this line of mice, firefly luciferase is expressed from the Dbp locus in a Cre recombinase-dependent manner, allowing assessment of bioluminescence rhythms in specific cellular populations. Our studies reveal cell-type-specific characteristics of rhythms among neuronal populations and liver cells. Our model allowed assessment of the rate of recovery from circadian misalignment once animals were provided with food ad libitum. These studies confirm the previously demonstrated circadian misalignment following environmental perturbations and reveal the utility of this model for minimally invasive, longitudinal monitoring of rhythmicity from specific mouse tissues.
Read the paper here.
Lighting Up Tumour Treatments
GibsonGroup COVID-19 work featured in Medical School Council Report
Darius Koester, Assistant Professor in the Division of Biomedical Sciences, tells us about his research looking at the interaction and dynamics of the cell surface.
Inspired minds, inspired places
The Division of Biomedical Sciences has a vision to build world-class Discovery Science and Translational Medicine programmes in partnership with the University Hospital Coventry & Warwickshire (UHCW), deliver interdisciplinary educational programmes and transmit new knowledge to the wider world through an exciting public engagement interface. The divison is home to 41 Principal Investigators including both clinical and non-clinical academics, several jointly appointed with other departments to drive interdisciplinary work.
Leading edge research centres and programmes
Our Principal Investigators lead key University-wide research centres, externally supported research programmes and innovative education initiatives:
Leading edge research centres and programmes
Our Principal Investigators lead key University-wide research centres, externally supported research programmes and innovative education initiatives:
Events and seminars
BMS Seminar: Endometrial hypoxia and menstruation, Dr Jacqueline Maybin, Senior Clinical Research Fellow and Honorary Consultant Gynaecologist, MRC Centre for Reproductive Health at University of Edinburgh
BMS Seminar: Dr Ying Chow, Assistant Professor, Department of Physics, University of Warwick
BMS Seminar: Dr Timothy Saunders, Associate Professor in Human Disease Biology, Division of Biomedical Sciences, Warwick Medical School, University of Warwick
BMS Seminar: Rethinking the neural crest – Cyclical Fate Restriction, Professor Robert Kelsh, Department of Biology and Biochemistry, University of Bath
Biomedical Sciences News
Cell-Type-Specific Circadian Bioluminescence Rhythms in Dbp Reporter Mice
In collaboration with groups at UMass Med School, Smith College and Morehouse University, we have developed a reporter mouse generated by modification of a widely expressed and highly rhythmic gene encoding D-site albumin promoter binding protein (Dbp). In this line of mice, firefly luciferase is expressed from the Dbp locus in a Cre recombinase-dependent manner, allowing assessment of bioluminescence rhythms in specific cellular populations. Our studies reveal cell-type-specific characteristics of rhythms among neuronal populations and liver cells. Our model allowed assessment of the rate of recovery from circadian misalignment once animals were provided with food ad libitum. These studies confirm the previously demonstrated circadian misalignment following environmental perturbations and reveal the utility of this model for minimally invasive, longitudinal monitoring of rhythmicity from specific mouse tissues.
Read the paper here.
Lighting Up Tumour Treatments
GibsonGroup COVID-19 work featured in Medical School Council Report
Darius Koester, Assistant Professor in the Division of Biomedical Sciences, tells us about his research looking at the interaction and dynamics of the cell surface.