Skip to main content Skip to navigation

Warwick Medical School

WMS Events Calendar

Please see this page for MB ChB events.

Wednesday, August 14, 2024

Select tags to filter on
Tue, Aug 13 Today Thu, Aug 15 Jump to any date

Search calendar

Enter a search term into the box below to search for all events matching those terms.

Start typing a search term to generate results.

How do I use this calendar?

You can click on an event to display further information about it.

The toolbar above the calendar has buttons to view different events. Use the left and right arrow icons to view events in the past and future. The button inbetween returns you to today's view. The button to the right of this shows a mini-calendar to let you quickly jump to any date.

The dropdown box on the right allows you to see a different view of the calendar, such as an agenda or a termly view.

If this calendar has tags, you can use the labelled checkboxes at the top of the page to select just the tags you wish to view, and then click "Show selected". The calendar will be redisplayed with just the events related to these tags, making it easier to find what you're looking for.
 
-
Export as iCalendar
BMS informal seminar: How meiotic chromosome segregation is established and regulated? Dr Yoshinori Watanabe, Science Center for Future Foods, Jiangnan University
A151 (MBU), Medical School Building

Abstract: In proliferating cells, sister chromatid cohesion is established depending on Rad21 cohesin complexes during S phase and maintained until metaphase, and required for equational chromosome segregation in mitosis. In meiosis, however, the cohesin complexes are largely replaced by meiosis-specific cohesin complexes including Rec8, thereby establishing reductional chromosome segregation to produce haploid gametes (Watanabe & Nurse, Nature 1999). In addition to Rec8, our lab has identified and characterized shugoshin (Sgo1) and meikin (Moa1) in fission yeast, which critically regulate the functions of Rec8. Importantly, these key meiotic factors and their functions turned out to be conserved in human. I will discuss how Rec8, Sgo1 and Moa1 interplay to establish meiotic chromosome segregation, and how disorder of the system influence egg aneuploidy, which is a major cause of miscarriage and congenital diseases such as Down syndrome in human.

More information | Tags: BiomedicalSciences DivisionalSeminars |

Placeholder