Trials A-Z
| E (no definitions) | G (no definitions) | J (no definitions) | L (no definitions) | |||||||||
| Q (no definitions) | U (no definitions) | X (no definitions) | Y (no definitions) | Z (no definitions) |
A
- ACTIVATES
Investigating whether an exercise programme is acceptable to patients, parents and physiotherapists and what training is required to deliver the treatments in NHS hospitals. (Published paper)
- ADAPT SEPSIS
BionmArker-guided Duration of Antibiotic treatment in hospitalised PaTients with suspected Sepsis: the ADAPT-Sepsis Trial
- AIR
Assessing the difference in the Manchester-Oxford Foot and Ankle Questionnaire at six months after injury between adults with an ankle fracture treated with functional bracing and exercises versus standard plaster cast care.
- AIR Main
UK study of ankle fracture rehabilitation – multicentre randomised controlled trial
- ALIFE2
Anticoagulants for LIving FoEtuses in women with recurrent miscarriage and inherited thrombophilia
- ARTemis
Determining whether the addition to neo-adjuvant chemotherapy of an anti-angiogenic agent bevacizumab is more effective than standard chemotherapy alone in terms of short-term and long-term outcome in women presenting with HER2-negative early breast cancer.
- ARTISAN
Acute Rehabilitation following Traumatic anterior shoulder dISlocAtioN (ARTISAN): A Multi Centre Randomised Controlled Trial
- ATM
Comparing Platelet Rich Plasma (PRP) to placebo (imitation) injection in adults with Achilles tendon pain
- ATNEC
Axillary management in T1-3N1M0 breast cancer patients with needle biopsy proven nodal metastases at presentation after neoadjuvant chemotherapy
B
- BALTI-2
Investigating whether salbutamol improves the health of patients with acute respiratory distress syndrome (ARDS). (Published Paper)
- BALTI-prevention
Investigating the effectiveness of inhaled salmeterol for the prevention of acute lung Injury/Acute Respiratory Distress Syndrome (ARDS) in patients at high risk of developing the condition. (Published paper)
- Best
A multi-centred randomised controlled trial of a primary-care based cognitive behavioural program for low back pain. (Published paper)
- Big Baby
Induction of labour for predicted macrosomia - The 'Big Baby Trial'
- Breathe
Protocolised trial of invasive and non-invasive weaning off ventilation.
C
- Cerm
Chronic Endometritis and Recurrent Miscarriage - The CERM trial
- CHESS
Investigating the management of chronic headaches.
- COMPRESS-RCT
A feasibility randomised controlled trial of mechanical chest compression devices for in-hospital cardiac arrest
D
- DAPA
To answer the question: Does a programme of exercise and physical activity improve cognition for people with mild to moderate dementia?
- De-ESCALaTE HPV
Determining the optimum treatment for patients with HPV+ OPSCC.
- DRAFFT
A randomised controlled trial of percutaneous fixation with Kirschner wires versus volar locking-plate fixation in the treatment of adult patients with a dorsally displaced fracture of the distal radius
F
- FASHIoN
Designed to help decide on the best treatment for hip impingement so that we can care for you and others with hip impingement more effectively in the future.
- FIS
Assessing the clinical and cost-effectiveness of facet joint injections compared to best usual non-invasive care in patients with persistent non-specific low back pain.(Published paper)
- FixDT
Comparing intramedullary nail fixation with locking plate fixation for patients with a distal tibia fracture.
H
- HeFT
To investigate whether surgery by open reduction and internal fixation provides benefit compared with non-operative treatment for displaced, intra-articular calcaneal fractures. (Published paper )
I
- IMPACT-LBP
Investigating the effect of using decision aid on available treatment options for patients with non specific chronic low back pain and their decision making process, on the patient's satisfaction levels. (Published Paper)
- I-WOTCH
Improving the Wellbeing of people with Opioid Treated Chronic pain.
K
- KOPS
Investigating why total Knee Arthroplasty (TKA) is a treatment that has a proven benefit; however a proportion of people, possibly as high as one in six, have less satisfactory outcomes after surgery.
M
- MAMMO-50
Mammographic surveillance in breast cancer patients aged 50 years or older.
- Metro
Meniscal tear outcome study (METRO). The purpose of this study is find out what is the current management of young patients (patients under 55) with meniscal tears in the population and what happens to these patients
N
- Neo-escape
A trial looking at chemotherapy before and after surgery for advanced peritoneal cancer
O
- OHCAO
A research database to identify best practice and improve patient outcomes for those suffering pre-hospital cardiac arrest.
- OPERA
Investigating effectiveness and cost-effectiveness of a whole home physical activity intervention to reduce depression in older people in residential and nursing homes. (Published Protocol)
- OPTIMA
Optimal Personalised Treatment of early breast cancer using Multi-parameter Analysis
P
- PARAMEDIC
Examining whether a new mechanical chest compression device (called LUCAS-2) improves survival in victims of cardiac arrest. (Published Paper)
- PARAMEDIC 2
This trial looks at whether adrenaline is helpful or harmful in the treatment of a cardiac arrest that occurs outside a hospital. Answering this question will help to improve the treatment of people who have a cardiac arrest.
- PARAMEDIC-3
The PARAMEDIC-3 trial is looking at the most effective way to treat someone when their heart suddenly stops working out of hospital by giving drugs through a vein or into the bone. Answering this question will help to improve future treatment of people who have a cardiac arrest.
- Persephone
Comparing six months Herceptin® treatment with twelve months, in patients with early stage breast cancer.
- PET-NECK
Comparing PET-CT guided watch and wait policy versus planned neck dissection for the management of locally advanced (N2/N3) nodal metastases in patients with head and neck squamous cancer. (Published paper)
- PIPA
An online Parenting Intervention to Prevent affective disorders in high-risk Adolescents
- PIPS
A Feasibility Study into Patellla Instability: Physiotherapy or Surgery
- POSED
A feasibility study of Prehospital Optimal Shock Energy for Defibrillation (POSED)
- Pre-FIT
What is the comparative effectiveness of advice, exercise and a multi-factorial fall prevention (MFFP) programme on peripheral fractures among older people living in the community?
- Prosper
Comparing usual care (written information leaflets) versus a physiotherapist-led exercise programme for women at high risk of developing shoulder problems after breast cancer treatment.
R
- RACER-Knee
Robotic Arthroplasty: a Clinical and cost Effectiveness Randomised controlled trial (RACER)
- RECOVERY - RS
RECOVERY - Respiratory Support: Respiratory Strategies in COVID-19; CPAP, High-flow, and standard care
- REGAIN
Rehabilitation Exercise and psycholoGical support After covid-19 InfectioN
- REGARD
A Feasibility Randomised Controlled Trial to compare REgional versus General Anaesthesia in Reducing Delirium in patients with Hip Fractures
- RESPECT
To determine, in adults admitted to acute NHS hospitals, how, when and why are emergency care and treatment plans made and what effects do they have on patient care?
- RISE
Return to work with Individualised Supported Employment (RISE)
S
- SAFE-TKR
Safety and Feasibility Evaluation of Tourniquets for Total Knee Replacement
- SARAH
Investigating two approaches to treatment for Rheumatoid Arthritis (RA) affecting the hands.
- SELECT-D
Anticoagulation Therapy in SELECTeD Cancer Patients at Risk of Recurrence of Venous Thromboembolism (VTE)
- SOS
Sugar or Salt (SOS) trial: Hyperosmolar therapy in traumatic brain injury
- SPHERe
Supervised Pulmonary Hypertension Exercise Rehabilitation (SPHERe) trial
- START:REACTS
Sub-acromial spacer for Tears Affecting Rotator cuff Tendons: a Randomised, Efficient, Adaptive Clinical Trial in Surgery (START:REACTS)
- STRESS-L
Stress-L: STudy into the REversal of Septic Shock with Landiolol (Beta Blockade)
T
- TEAMM
Assessing the benefit of antibiotic prophylaxis and its effect on healthcare associated infection
V
- VITAL
Volatile vs Total intravenous Anaesthesia for major non-cardiac surgery
W
- WHiTE
Looking at the clinical and cost effectiveness of treatments of fracture of the proximal femur.
- WOLLF
A trial of standard care wound management versus negative pressure wound therapy in the treatment of adult patients with an open fracture of the lower limb.