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Prof Jonathan Millar

Job Title
Professor
Department
WMS - Biomedical Sciences
Phone
02476150414
Web Link
Research Interests

My laboratory has had a long-standing interest in the fundamental mechanisms that regulate the cell division cycle. We have made fundamental discoveries on how cells trigger entry into mitosis (Millar et al., 1991; Millar and Russell, 1992), how this transition is regulated by environmental stress (Millar et al., 1995, López-Avilés et al., 2005) and how cells ensure chromosomes are only replicated once per cell cycle (Wuarin et al., 2002). More recently we have uncovered novel factors required for the retrieval and bi-orientation of sister chromatids (Sanchez-Perez et al., 2005, Franco et al., 2007) and identified an evolutionarily conserved mechanism that switches of the spindle checkpoint (Vanoosthuyse et al., 2009; Meadows et al., 2011). I am currently a member of the Faculty of 1000 and an Editor of Seminars in Cell and Developmental Biology.

For more information please visit my laboratory home pageor my Researchgate Profile home page.

Biography

I did my PhD with Dr. Enrique Rozengurt at the Cancer Research UK Laboratories in London (then ICRF) on signalling mechanisms in the early mitogenic response and then spent four years as post-doctoral fellow in the laboratory of Professor Paul Russell at The Scripps Research Institute in San Diego (U.S.A.). In 1994 I moved back to the U.K. to take up a tenure track position at the National Institute for Medical Research in London and received tenure in 2000. In 2006 I moved to the University of Warwick to take up a Professorship in Cell Biology.

Title Funder Award start Award end
MRC DTP - Period 2 - Oct 2016 - Sept 2020 Ideate 47778 (Period 1 May 2016 - Sept 16) Ideate 48728 (Period October 2020 - September 2022) MRC 01 Oct 2016 30 Sep 2022
Mechanisms of spindle checkpoint silencing (Programme Grant renewal) MRC 01 Jan 2013 30 Jun 2018
Regulation of chromosome bi-orientation MRC 01 Jun 2007 30 Sep 2012
Mechanisms controlling bi-polar spindle assembly in fission yeast - Transfer from NIMR Association for International Cancer Research 01 Oct 2007 31 Mar 2008