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Wellcome Bioimaging Award - A Multi-modal Imaging Platform Using Light-Sheet and Photostable Probes for Quantitative Cell and Tissue-Scale Biology
Satyajit Mayor, Mohan Balasubramanian and Masanori Mishima along with a group in the USA (Abhishek Kumar at Marine Biological laboratories- MBL- WoodsHole) have been awarded a Wellcome Trust Bioimaging Award.
In Phase 1 of this project, feasibility, proof-of-principle, and ease of use of the prototype light-sheet system with three detection modalities using existing and new fluorescent proteins will be established. In Phase 2, we explore a breadth of biological questions through investigation of model membranes, cultured cells (yeast, mammalian), and animal models (nematode, fly, fish). Our ultimate goal is to develop transformative imaging technology including optics and probes for widespread use by quantitative cell biologists everywhere.