Tuberculosis is a devastating disease that claims over 1.5 million lives each year. The increase in TB cases that are resistant to the current antibiotics means that novel drugs to kill Mycobacterium tuberculosis (Mtb) are urgently needed. Researchers from the University of Warwick have successfully discovered how Mycobacterium tuberculosis uses an essential sugar called trehalose, which provides a platform to design new and improved TB drugs and diagnostic agents.
New insight on the physical interactions that take place between swarming bacteria when exposed to antibiotics could lead to novel approaches for treating infections in patients.
An approach to public engagement which respects grass-roots and community knowledge has an important role to play in improving our understanding of the relationship between traditional healing and Western-style medicine in low and middle-income countries, and could generate new approaches to tackling antimicrobial resistance, according to a new paper published in Medical Humanities.
Antibiotic resistance is an increasing battle for scientists to overcome, as more antimicrobials are urgently needed to treat biofilm-associated infections. However scientists from the School of Life Sciences at the University of Warwick say research into natural antimicrobials could provide candidates to fill the antibiotic discovery gap.