Events @ Warwick Chemistry
Chelators in radiopharmaceuticals: new applications for existing ligands in diagnostic imaging
Michelle Ma from King's College will be giving a Synthesis and Catalysis Cluster Seminar in PLT and on Teams.
Abstract: Radioactive metals have applications in nuclear medicine for diagnosis and localisation of disease, and in systemic radiotherapy treatments. Recently, new molecular radiopharmaceuticals based on radiometal-labelled peptides have demonstrated high clinical utility. My group’s research focuses on developing chelator platforms that efficiently incorporate radiometals into disease-targeting peptides and proteins. In this seminar I outline three examples showing how we have adapted existing chelators to enable their attachment to peptides and proteins, and subsequently applied these newly functionalised chelators to image disease at the whole-body level.
Biosketch: I work at the interface of bioconjugate, inorganic and radio chemistry research, developing and applying chelators for binding radioactive metal ions used in diagnostic and therapeutic radiopharmaceuticals. I received my PhD from the University of Melbourne in 2010. In 2012, I moved to London to take up Marie Curie and Royal Society Newton International Fellowships at King’s College London. I am currently a Senior Lecturer and a Cancer Research UK Career Establishment Fellow at King’s College London. In my spare time, I enjoy reading, dancing (badly) and binging on Netflix.
If you would like to attend her talk in person, please add your name to this doodle poll, as spaces are limited: https://doodle.com/poll/zcuizkd4w9mgzrws?utm_source=poll&utm_medium=link.
Otherwise, feel free to join us on Teams (see link below and calendar invite):
Microsoft Teams meeting
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