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Dr Nicola Rogers MRSC


Dr Nicola Rogers
Senior Research Fellow

(Scott Group)

MSci(Birmingham), PhD(Birmingham)


Research Summary

In the Scott Group we develop self-assembled chiral metal complexes, many of which exhibit biological activity. Throughout my PhD and PDRA positions, my research has focused on molecular imaging agents for diagnostic techniques in medicine. I also have research interests in the development of new transition-metal MRI contrast agents, with a move away from traditional Gd systems.

Selected Publications

'Discovery of selective, antimetastatic and anti-cancer stem cell metallohelices via post-assembly modification', H. Song, N. J. Rogers, S. J. Allison, V. Brabec, H. Bridgewater, H. Kostrhunova, L. Markva, R. M. Phillips, E. C. Pinder, S. L. Shepherd, L. S. Young, J. Zajac, and P. Scott, Chem. Sci., 10, 8547-8557 (2019).

'Metallohelices that kill Gram-negative pathogens using intracellular antimicrobial peptide pathways', D. H. Simpson, A. Hapeshi, N. J. Rogers, V. Brabec, G. J. Clarkson, D. J. Fox, O. Hrabina, G. L. Kay, A. K. King, J. Malina, A. D. Millard, J. Moat, D. I. Roper, H. Soing, N. R. Waterfield, and P. Scott, Chem. Sci., 10, 9708-9720 (2019).

Tailoring iridium luminescence and gold nanoparticle size for imaging of microvascular blood flow‘, N. J. Rogers, H. C. Jeffery, S. Claire, D. J. Lewis, G. Zikeli, N. J. Hodges, S. Egginton, G. B. Nash, Z. Pikramenou, , Nanomedicine (Lond), 12, 2725-2740 (2017).

Simultaneous triple imaging with two PARASHIFT probes: encoding anatomical information, pH and temperature using magnetic resonance shift imaging’,K-L. N. A. Finney, A. C. Harnden, N. J. Rogers, D. O’Hogain, P. K. Senanayake, A. Blamire, D. Parker, Chem. Eur. J. 23, 7976-7989 (2017).

PARASHIFT Probes: Solution NMR and X-ray Structural Studies of Macrocyclic Ytterbium and Yttrium Complexes’, K. Mason, N. J. Rogers, E. A. Suturina, I. Kuprov, J. A. Aguilar, A, S, Batsanov, D. S. Yufit, D. Parker, Inorg. Chem.56, 4028-4038 (2017).

Molecular hydrogen and catalytic combustion in the production of hyperpolarized 83Kr and 129Xe MRI contrast agents’, N. J. Rogers, F. Hill-Casey, K. F. Stupic, J. S. Six, C. Lesbats, S. P. Rigby, J. Fraissard, G. E. Pavlovskaya, T. Meersmann, PNAS, 113, 3164-3168 (2016).

A new paramagnetically shifted imaging probe for MRI’, P. K. Senanayake, N. J. Rogers, K.-L. N. A. Finney, P. Harvey, A. M. Funk, J. I. Wilson, D. O’Hogain, R. Maxwell, D. Parker, A. M. Blamire, Magn. Reson. Med., 77, 1307-1317 (2017).

Another challenge to paramagnetic relaxation theory: a study of paramagnetic proton NMR relaxation in closely related series of pyridine-derivatized dysprosium complexes’, N. J. Rogers, K.-L. N. A. Finney, P. K. Senanayake, D. Parker, Phys. Chem. Chem. Phys., 18, 4370-4375 (2016).

Critical analysis of the limitations of Bleaney’s theory of magnetic anisotropy in paramagnetic lanthanide coordination complexes’, A. M. Funk, K.-L. N.A. Finney, P. Harvey, A. M. Kenwright, E. R. Neil, N. J. Rogers, P. K.Senanayake, D. Parker, Chem. Sci., 6,1655 (2015).

'High coating of Ru(II) complexes on gold nanoparticles for single particle luminescence imaging in cells‘, N. J. Rogers, S. Claire, G. Zikeli, S. Farabi, R. Harris, N. J. Hodges, I. Styles, Z. Pikramenou, ‘, Chem. Commun., 50, 617 (2014).


N. J. Rogers and Z. Pikramenou (50 %), University of Birmingham, ‘Composition used to image cells, mark biomolecules, incorporate nanoparticles into cells and monitor flow of marked biomolecules, comprises nanoparticles of noble metal (e.g. boron) functionalized with metal complex and surfactant’, Patent WO2013004989-A1, (2013).

Thomas Meersmann, Nicola (Rogers) Simpson, Galina Pavlovskaya, University of Nottingham, 'Production of Hyperpolarized Gas', Patent filed 2016, PCTGB2016052730, WO2017042544.

Review Articles

Electromagnetic susceptibility anisotropy and its importance for paramagnetic NMR and optical spectroscopy in lanthanide coodination chemistry’, O. A. Blackburn, R. M. Edkins, S. Faulkner, A. M. Kenright, D. Parker, N. J. Rogers, S. Shuvaev, Dalton Trans.,45, 6782-6800 (2016).

Biological applications of nanomaterials’, N. J. Rogers, D. J. Lewis, , Nanoscience: Volume 3, 3, 276-323 (2016).