Current projects

Current projects include medicinal chemistry for specific enzyme inhibitors, synthetic methodology for unusual heterocycles, as well as collaborations with RxCelerate Ltd.

Research interests

Synthetic organic and medicinal chemistry

• Drug discovery and development.
• Synthetic methodology including asymmetric and catalytic reactions.
• Scale-up route design

Teaching and supervision

David Fox teaches in undergraduate modules CH222 Speclab, CH271, CH3E9, and CH408.

I am supervising the following PhD and MSc students:

• Matthew Clayton, medicinal chemistry
• Matthew Taylor, computational drug discovery
• Emma Scott, synthetic methodology
• Emily Williams, synthetic methodology
• Annabel Page, synthetic methodology

Publications

Selected Publications

• Synthesis and characterization of triangulene
  Niko Pavliček, Anish Mistry, Zsolt Majzik, Nikolaj Moll, Gerhard Meyer, David J. Fox and Leo Gross, Nature Nanotechnology 2017, doi:10.1038/nnano.2016.305
• Total synthesis of the azolemycins
  Zoe J. Anderson, David J. Fox Org. Biomol. Chem., 2016, DOI: 10.1039/C5OB02520f
• Stereo- and Chemodivergent NHC-Promoted Functionalisation of Arylalkylketenes with Chloral
  J. J. Douglas, G. Churchill, A. M. Z. Slawin, D. J. Fox and A. D. Smith Chem. Eur. J., 2015, 21, 16354-16358 DOI: 10.1002/chem.201503308.
• The Synthesis and STM/AFM Imaging of ‘Olympicene’ Benzo[cd]pyrenes
  Anish Mistry, Ben Moreton, Bruno Schuler, Fabian Mohn, Gerhard Meyer, Leo Gross, Antony Williams, Peter Scott, Giovanni Costantini and David J. Fox Chem. Eur. J. 2015, 21, 2011-2018. DOI: 10.1002/chem.201404877
• Trichloromethyl ketones: asymmetric transfer hydrogenation and subsequent Jocic-type reactions with amines
  Perryman, Michael S.; Harris, Matthew E.; Foster, Jade L.; Joshi, Anushka; Clarkson, Guy J.; Fox, David J. Chem Commun., 2013, 49, 10022-10024. DOI:10.1039/c3cc46070c This paper was highlighted in Synfacts 2014, 10, 175. DOI:10.1055/s-0033-1340532

Further PublicationsLink opens in a new window