Complexity Forum
Complexity Forum - Konstantin Blyuss
Speaker: Konstantin Blyuss (Bristol Complexity)
Title: "Mathematical modelling of multi-strain diseases"
Abstract: In this talk I will discuss challenges of modelling the dynamics of multi-strain infections using the examples of malaria and dengue fever. In the first model, I will show how "bifurcations without parameters" provide an understanding of the phase space of the system and explain the numerical simulations of the interactions between malaria parasite and a human immune system. I will also demonstrate that the assumption of external seasonal forcing, which is often used to reproduce observed temporal patterns of dengue fever, is not necessary, and the dynamics can be fully explained by the
interaction of dengue serotypes.
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