Day

Start

Session

Speaker

Title

Monday

13:00

Arrival

all

13:30

Welcome

Dallmann

Are we there yet? A fast-paced race towards molecular biomarkers of the clock.

14:00

Clinical use cases

Zee

Rhythms in ICU

14:30

Montagnese

Chronotyping between questionnaires, wearables and molecular markers

Break

15:30

Anafi

Tumor circadian clock strength influences metastatic potential and predicts patient prognosis in Luminal A breast cancer

16:00

Ruben

24 h physiological rhythms in hospitalized patients

16:30

General Discussion

Break

17:30

Systems Biology of Clocks

Ueda

TBC

19:30

Dinner

Tuesday

9:00

From mathematical concepts to biomarker candidates

Forger

Modeling and validating circadian rhythm biomarkers

9:30

Rand

What clock functionality is accessible from a single transcriptomics sample?

10:00

Ananthasubramaniam

Machine learning approaches to quantifying circadian rhythms in humans

Break

11:00

From concepts to applications 2

Dijk

The promise and pitfalls of biomarker discovery for sleep and circadian processes

11:30

Kim

Digital circadian biomarkers for mood disorders and daytime sleepiness disorder

12:00

Kramer

Transcriptional biomarkers "in the wild"

12:30

Lunch

14:30

From concepts to applications 3

Hut

Clocks in the Clinic: Body Clock?? What Body Clock?!

15:00

Specht/Mignot

Studying the circadian clock and sleep homeostasis using proteomic data

15:30

Wright

Assessing central and peripheral circadian timing with omics in humans

Break

16:30

Naef

Circadian phase inference in human tissues and in single cells

17:00

Lightman

Automated wearable sampling systems in human studies of interstitial fluid biomarkers

Break

18:00

Circadian biomarker must haves

General Discussion

19:30

Dinner

Wednesday

9:00

Consequences for pharmacotherapeutics

Lehr

TBC

9:30

Finkenstadt

TBC

Break

10:30

Discussion

all

Concluding discussion and further plan

12:00

Thanks and farewell