Job Title
Associate Professor (Teaching Focussed)
Department
WMS - Biomedical Sciences
Email
Research Interests
Research interests include the molecular basis for immune system interactions with their environments, especially the role of glycobiology and the complement system in pathogen recognition and cellular communication in host tissues. Recent work involves the analysis of polymer-protein and polymer-cell interactions in healthcare, drawing upon strengths in polymer chemistry at Warwick. These studies are being developed alongside clinical studies in renal transplantation at the University Hospital, Coventry.
Biography
Dan's research carried out as part of the PhD degree (awarded in 2000 from Imperial College) involved the genetics of autoimmune disease and the role of innate immune mechanisms in autoimmunity and inflammation. This work was carried out with Marina Botto and Mark Walport. Postdoctoral work at the Oxford Glycobiology Institute with Kurt Drickamer involved the post-genomic study of protein-oligosaccharide interactions within the immune system, especially those encountered in HIV infection. Subsequent work with Bob Sim at the MRC Immunochemistry Unit in Oxford involved the investigation of the immune system in prion diseases such as scrapie and BSE. Several significant publications have emerged from these collective studies, including papers in Science and Nature Medicine.
- 'Beirag, Nazar, 'Kumar, Chandan, 'Madan, Taruna, 'Shamji, Mohamed H., 'Bulla, Roberta, 'Mitchell, Daniel A., 'Murugaiah, Valarmathy, 'Neto, Martin Mayora, 'Temperton, Nigel, 'Idicula-Thomas, Susan, 'Varghese, Praveen M., 'Kishore, Uday, 2022. 'Human surfactant protein D facilitates SARS-CoV-2 pseudotype binding and entry in DC-SIGN expressing cells, and downregulates spike protein induced inflammation. Frontiers in Immunology, 13
- Villar, Javiera, Salazar, Michelle L., Jiménez, José M., Campo, Miguel Del, Manubens, Augusto, Gleisner, María Alejandra, Ávalos, Ignacio, Salazar?Onfray, Flavio, Salazar, Fabián, Mitchell, Daniel A., Alshahrani, Mohammad Y., Martínez?Pomares, Luisa, Becker, María Inés, 2021. C?type lectin receptors MR and DC?SIGN are involved in recognition of hemocyanins, shaping their immunostimulatory effects on human dendritic cells. European Journal of Immunology, 51 (7), pp. 1715-1731
- Babu, Adarsh, Khovanova, N. A., Shaw, Olivia, Griffin, Sian, Briggs, David, Krishnan, Nithya S., Fletcher, Simon, Imray, Christopher H.E., Seitz, Adrienne, Baker, Richard, Wellberry?Smith, Matthew, Clarke, Brendan, Cullen, Katherine, Rees, Tracey, Edwards, Frankie, Burrows, Emma, Howe, Louise, Martin, Chloe, Dorling, Anthony, Zehnder, Daniel et al (Select to open full list), 2020. C3d?positive donor?specific antibodies have a role in pretransplant risk stratification of cross?match?positive HLA?incompatible renal transplantation : United Kingdom multicentre study. Transplant International, 33 (9), pp. 1128-1139
- Mitchell, Daniel A., Fayter, Alice, Deller, Robert C., Hasan, Muhammad, Gutierrez-Marcos, José F., Gibson, Matthew I., 2019. Ice-recrystallization inhibiting polymers protect proteins against freeze-stress and enable glycerol-free cryostorage. Materials Horizons, 6 (2), pp. 354-368
- Almitairi, Jamal O. M., Venkatraman Girija, Umakhanth, Furze, Christopher M., Simpson-Gray, Xanthe, Badakshi, Farah, Marshall, Jamie E., Schwaeble, Wilhelm J., Mitchell, Daniel A., Moody, Peter C. E., Wallis, Russell, 2018. Reply to Mortensen et al.: The zymogen form of complement component C1. Proceedings of the National Academy of Sciences of the United States of America, 115 (17), pp. E3867-E3868
- Daga, Sunil, Moyse, Harry, Briggs, David, Lowe, David Philip, Evans, Neil D., Jones, James, Buchli, Rico, McMurtrey, Curtis, Mulder, Arend, Hildebrand, William, Claas, Frans, Higgins, Rob, Mitchell, Daniel A., Zehnder, Daniel, 2018. Direct quantitative measurement of the kinetics of HLA-specific antibody interactions with isolated HLA proteins. Human Immunology, 79 (2), pp. 122-128
- Mitchell, Daniel A., Zhang, Qiang, Voorhaar, Lenny, Haddleton, David M., Herath, Shan, Gleinich, Anne S., Randeva, Harpal S., Crispin, Max, Lehnert, Hendrik, Wallis, Russell, Patterson, Steven, Becer, C. Remzi, 2017. Manipulation of cytokine secretion in human dendritic cells using glycopolymers with picomolar affinity for DC-SIGN. Chemical Science, 8 (10), pp. 6974-6980
- Dilly, Suzanne J., Clark, Andrew J., Marsh, Andrew, Mitchell, Daniel A., Cain, Ricky, Fishwick, Colin W. G., Taylor, Paul C., 2017. A chemical genomics approach to drug reprofiling in oncology : antipsychotic drug risperidone as a potential adenocarcinoma treatment. Cancer Letters, 393, pp. 16-21
- Tanaka, Joji, Gleinich, Anne S., Zhang, Qiang, Whitfield, Richard, Kempe, Kristian, Haddleton, David M., Davis, Thomas P., Perrier, Sébastien, Mitchell, Daniel A., Wilson, Paul, 2017. Specific and differential binding of N-acetylgalactosamine glycopolymers to the human macrophage galactose lectin and asialoglycoprotein receptor. Biomacromolecules, 18 (5), pp. 1624-1633
- Thomas, Michael, Snead, David, Mitchell, Daniel A., 2017. An investigation into the potential role of brain angiogenesis inhibitor protein 3 (BAI3) in the tumorigenesis of small-cell carcinoma : a review of the surrounding literature. Journal of receptor and signal transduction research, 37 (4), pp. 325-334
- Zhang, Yan, Briggs, David, Lowe, David Philip, Mitchell, Daniel A., Daga, Sunil, Krishnan, Nithya, Higgins, Rob, Khovanova, N. A., 2017. A new data-driven model for post-transplant antibody dynamics in high risk kidney transplantation. Mathematical Biosciences, 284, pp. 3-11
- Zhang, Hongtao, Palma, Angelina S., Zhang, Yibing, Childs, Robert A., Liu, Yan, Mitchell, Daniel A., Guidolin, Leticia S., Weigel, Wilfried, Mulloy, Barbara, Ciocchini, Andrés E., Feizi, Ten, Chai, Wengang, 2016. Generation and characterization of ß1,2-gluco-oligosaccharide probes fromBrucella abortuscyclic ß-glucan and their recognition by C-type lectins of the immune system. Glycobiology, 26 (10), pp. 1086-1096
- Sanghera, Narinder, Anderson, Alexander, Nuar, Nick, Xie, Can, Mitchell, Daniel A., Klein-Seetharaman, Judith, 2016. Insulin biosensor development : a case study. International Journal of Parallel, Emergent and Distributed Systems, 32 (1), pp. 119-138
- Deller, Robert C., Pessin, Jeffrey E., Vatish, Manu, Mitchell, Daniel A., Gibson, Matthew I., 2016. Enhanced non-vitreous cryopreservation of immortalized and primary cells by ice-growth inhibiting polymers. Biomaterials Science, 4 (7), pp. 1079-1084
- Page, Ashley M., Perry, David, Young, Philip J., Mitchell, Daniel A., Frenguelli, Bruno G., Unwin, Patrick R., 2016. Fast nanoscale surface charge mapping with pulsed-potential scanning ion conductance microscopy. Analytical Chemistry, 88 (22), pp. 10854-10859
- Page, Ashley, Perry, David, Young, Philip J., Mitchell, Daniel Anthony, Frenguelli, Bruno G., Unwin, Patrick R., 2016. Fast nanoscale surface charge mapping with pulsed-potential scanning ion conductance microscopy. Analytical Chemistry, 88 (22), pp. 10854-10859
- Marsh, Andrew, Casey-Green, Katherine, Probert, Fay, Withall, David M., Mitchell, Daniel A., Dilly, Suzanne J., James, Sean G., Dimitri, W., Ladwa, Sweta R. L., Taylor, Paul C., Singer, Donald R. J., 2016. Simvastatin sodium salt and fluvastatin interact with human gapjunction gamma-3 protein. PLoS One, 11 (2), pp. 1-27
- Higgins, Rob, Daga, Sunil, Mitchell, Daniel A., 2015. Antibody-incompatible kidney transplantation in 2015 and beyond. Nephrology, Dialysis, Transplantation, 30 (12), pp. 1972-1978
- Girija, Umakhanth Venkatraman, Furze, Christopher M., Gingras, Alexandre R., Yoshizaki, Takayuki, Ohtani, Katsuki, Marshall, Jamie E., Wallis, A. Katrine, Schwaeble, Wilhelm J., El-Mezgueldi, Mohammed, Mitchell, Daniel A., Moody, Peter C. E., Wakamiya, Nobutaka, Wallis, Russell, 2015. Molecular basis of sugar recognition by collectin-K1 and the effects of mutations associated with 3MC syndrome. BMC biology, 13 (1), pp. 1-13
- Lowe, David Philip, Daga, Sunil, Briggs, David, Khovanova, N. A., Mitchell, Daniel A., Higgins, Rob, Krishnan, N., 2015. Meeting report : 3rd international transplant conference: how much risk can you take?. International Journal of Immunogenetics, 42 (2), pp. 59-68
- Semblat, Jean-Philippe, Ghumra, Ashfaq, Czajkowsky, Daniel M., Wallis, Russell, Mitchell, Daniel A., Raza, Ahmed, Rowe, J. Alexandra, 2015. Identification of the minimal binding region of a Plasmodium falciparum IgM binding PfEMP1 domain. Molecular and Biochemical Parasitology, 201 (1), pp. 76-82
- Girija, Umakhanth Venkatraman, Furze, Christopher M., Gingras, Alexandre R., Yoshizak, Takayuki, Ohanti, Katsuki, Marshall, Jamie E., Wallis, A. Katrine, Schwaeble, Wilhelm J., El-Mezgaeldi, Mohammed, Mitchell, Daniel A., Moody, Peter C. E., Wakamiya, Nobutaka, Wallis, Russell, 2015. Molecular basis of sugar recognition by collectin-K1 and the effects of mutations associated with 3MC syndrome. Biomed Central Public Health, 13, pp. 1-13
- Czajkowsky, Daniel M., Andersen, J. T., Fuchs, Anne, Wilson, T. J., Mekhaie, D., Colonna, M., He, J., Shao, Zhiyuan, Mitchell, Daniel A., Wu, Gang, Dell, Anne, Haslam, S., Lloyd, K. A., Moore, Stephen J., Sandlie, I., Blundell, P. A., Richard, J. P., 2015. Developing the IVIG biomimetic, Hexa-Fc, for drug and vaccine applications. Scientific Reports, 5
- Semblat, Jean-Philippe, Ghumra, Ashfaq, Czajkowsky, Daniel M., Wallis, Russell, Mitchell, Daniel Anthony, Raza, Ahmed, Rowe, J.Alexandra, 2015. Identification of the minimal binding region of a Plasmodium falciparum IgM binding PfEMP1 domain. Molecular and Biochemical Parasitology
- Khovanova, N. A., Daga, Sunil, Shaikhina, Torgyn, Krishnan, Nithya, Jones, James, Zehnder, Daniel, Mitchell, Daniel A., Higgins, Rob, Briggs, David, Lowe, David Philip, 2015. Subclass analysis of donor HLA-specific IgG in antibody-incompatible renal transplantation reveals a significant association of IgG4 with rejection and graft failure. Transplant International, 28 (12), pp. 1-11
- Pederson, Kari, Mitchell, Daniel A., Prestegard, James, 2014. Structural characterization of the DC-SIGN?LewisX Complex. Biochemistry, 53 (35), pp. 5700-5709
- Probert, Fay, Mitchell, Daniel A., Dixon, Ann M., 2014. NMR evidence for oligosaccharide release from the dendritic-cell specific intercellular adhesion molecule 3-grabbing non-integrin-related (CLEC4M) carbohydrate recognition domain at low pH. FEBS Journal, 281 (16), pp. 3739-3750
- Deller, Robert C., Vatish, Manu, Mitchell, Daniel A., Gibson, Matthew I., 2014. Synthetic polymers enable non-vitreous cellular cryopreservation by reducing ice crystal growth during thawing. Nature Communications, 5
- Zhang, Qiang, Su, Lu, Collins, Jennifer, Chen, Guosong, Wallis, Russell, Mitchell, Daniel A., Haddleton, David M., Becer, C. Remzi, 2014. Dendritic cell lectin-targeting sentinel-like unimolecular glycoconjugates to release an anti-HIV drug. Journal of the American Chemical Society, 136 (11), pp. 4325-4332
- Evans, Neil D., Moyse, Harry, Lowe, David Philip, Briggs, D., Higgins, Rob, Mitchell, Daniel A., Zehnder, Daniel, Chappell, M. J. (Michael J.), 2013. Structural identifiability of surface binding reactions involving heterogeneous analyte : application to surface plasmon resonance experiments. Automatica, 49 (1), pp. 48-57
- Abrams, William R., Madsen, Jens, Gaiha, Gaurav D., Palaniyar, Nades, Dong, Tao, Mitchell, Daniel A., Clark, Howard W., 2013. Surfactant protein D modulates HIV infection of both T-cells and dendritic cells. PLoS One, 8 (3)
- Zhang, Qiang, Collins, Jennifer, Anastasaki, Athina, Wallis, Russell, Mitchell, Daniel A., Becer, C. Remzi, Haddleton, David M., 2013. Sequence-controlled multi-block glycopolymers to inhibit DC-SIGN-gp120 binding. Angewandte Chemie International Edition, 52 (16), pp. 4435-4439
- Yu, Xiaojie, Vasiljevic, Snezana, Mitchell, Daniel A., Crispin, Max, Scanlan, Christopher N., 2013. Dissecting the molecular mechanism of IVIg therapy : the interaction between serum IgG and DC-SIGN is independent of antibody glycoform or Fc domain. Journal of Molecular Biology, 425 (8), pp. 1253-1258
- Girija, Umakhanth Venkatraman, Gingras, Alexandre R., Marshall, J. E., Panchal, R., Sheikh, M. A., Gal, P., Schwaeble, Wilhelm J., Mitchell, Daniel A., Moody, Peter C. E., Wallis, Russell, 2013. Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation. Proceedings of the National Academy of Sciences of the United States of America, 110 (34), pp. 13916-13920
- Huang, Jin, Zhang, Qiang, Li, Guang-Zhao, Haddleton, David M., Wallis, Russell, Mitchell, Daniel A., Heise, Andreas, Becer, C. Remzi, 2013. Synthetic glycopolypeptides as potential inhibitory agents for dendritic cells and HIV-1 trafficking. Macromolecular Rapid Communications, 34 (19), pp. 1542-1546
- Probert, Fay, Whittaker, S. B.- M, Crispin, Max, Mitchell, Daniel A., Dixon, Ann M., 2013. Solution NMR analyses of the C-type carbohydrate recognition domain of DC-SIGNR protein reveal different binding modes for HIV-derived oligosaccharides and smaller glycan fragments. Journal of Biological Chemistry, 288 (31), pp. 22745-22757
- Deller, Robert C., Congdon, Thomas, Sahid, Mohammed A., Morgan, Michael, Vatish, Manu, Mitchell, Daniel A., Notman, Rebecca, Gibson, Matthew I., 2013. Ice recrystallisation inhibition by polyols : comparison of molecular and macromolecular inhibitors and role of hydrophobic units. Biomaterials Science, 1 (5), pp. 478-485
- Hamer, Rizwan, Molostvov, Guerman, Lowe, David Philip, Satchell, Simon, Mathieson, Peter, Ilyas, Rebecca, Mitchell, Daniel A., Lam, For T., Kashi, Habib, Tan, Lam Chin, Imray, C. (Chris), Fletcher, Simon, Briggs, David, Krishnan, Nithya, Higgins, Rob, Zehnder, Daniel, 2012. Human leukocyte antigen-specific antibodies and gamma-interferon stimulate human microvascular and glomerular endothelial cells to produce complement factor C4. Transplantation, Vol.93 (No.9), pp. 867-873
- Girija, Umakhanth Venkatraman, Mitchell, Daniel A., Roscher, Silke, Wallis, Russell, 2011. Carbohydrate recognition and complement activation by rat ficolin-B. European Journal of Immunology, 41 (1), pp. 214-223
- Jiang, Yan, Kelly, Richard D. W., Peters, Amy, Fulka, Helena, Dickinson, Adam, Mitchell, Daniel A., St. John, Justin C., 2011. Interspecies somatic cell nuclear transfer is dependent on compatible mitochondrial DNA and reprogramming factors. PL o S One, Vol.6 (No.4)
- Gingras, Alexandre R., Girija, Umakhanth Venkatraman, Keeble, Anthony H., Panchal, Roshni, Mitchell, Daniel A., Moody, Peter C. E., Wallis, Russell, 2011. Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation. Structure, Vol.19 (No.11), pp. 1635-1643
- Dilly, Suzanne J., Clark, Andrew J., Mitchell, Daniel A., Marsh, Andrew, Taylor, Paul C., 2011. Using the Man9(GlcNAc)2 ? DC-SIGN pairing to probe specificity in photochemical immobilization. Molecular BioSystems, Vol.7 (No.1), pp. 116-118
- Ilyas, Rebecca, Wallis, Russell, Soilleux, Elizabeth J., Townsend, Paul, Zehnder, Daniel, Tan, Bee K., Sim, Robert B., Lehnert, Hendrik, Randeva, Harpal S., Mitchell, Daniel A., 2011. High glucose disrupts oligosaccharide recognition function via competitive inhibition : a potential mechanism for immune dysregulation in diabetes mellitus. Immunobiology, Vol.216 (No.1-2), pp. 126-131
- Ciobanu, Mihai, Huang, Kuo-Ting, Daguer, Jean-Pierre, Barluenga, Sofia, Chaloin, Olivier, Schaeffer, Evelyne, Mueller, Christopher G., Mitchell, Daniel A., Winssinger, Nicolas, 2011. Selection of a synthetic glycan oligomer from a library of DNA-templated fragments against DC-SIGN and inhibition of HIV gp120 binding to dendritic cells. Chemical Communications, Vol.47 (No.33), pp. 9321-9323
- Girija, Umakhanth Venkatraman, Furze, Christopher M., Toth, Julia, Schwaeble, Wilhelm J., Mitchell, Daniel A., Keeble, Anthony H., Wallis, Russell, 2010. Engineering novel complement activity into a pulmonary surfactant protein. Journal of Biological Chemistry, Vol.285 (No.10), pp. 546-552
- Hamer, Rizwan, Roche, Laura, Smillie, David, Harmer, Andrea, Mitchell, Daniel A., Molostvov, Guerman, Lam, For T., Kashi, Habib, Tan, Lam Chin, Imray, C. (Chris), Fletcher, Simon, Briggs, David, Lowe, David Philip, Zehnder, Daniel, Higgins, Rob, 2010. Soluble CD30 and Cd27 levels in patients undergoing HLA antibody-incompatible renal transplantation. Transplant Immunology, Vol.23 (No.4), pp. 161-165
- Becer, C. Remzi, Gibson, Matthew I., Geng, Jin, Ilyas, Rebecca, Wallis, Russell, Mitchell, Daniel A., Haddleton, David M., 2010. High-affinity glycopolymer binding to human DC-SIGN and disruption of DC-SIGN interactions with HIV envelope glycoprotein. Journal of the American Chemical Society, Vol.132 (No.43), pp. 15130-15132
- Carroll, Maria V., Sim, Robert B., Bigi, Fabiana, Jäkel, Anne, Antrobus, Robin, Mitchell, Daniel A., 2010. Identification of four novel DC-SIGN ligands on Mycobacterium bovis BCG. Protein & Cell, Vol.1 (No.9), pp. 859-870
- Wallis, Russell, Mitchell, Daniel A., Schmid, Ralf, Schwaeble, Wilhelm J., Keeble, Anthony H., 2010. Paths reunited: initiation of the classical and lectin pathways of complement activation. Immunobiology, Vol.215 (No.1), pp. 1-11
- Flores-Langarica, Adriana, Sebti, Yasmine, Mitchell, Daniel A., Sim, Robert B., MacPherson, Gordon G., 2009. Scrapie pathogenesis : the role of complement C1q in scrapie agent uptake by conventional dendritic cells. Journal of Immunology, Vol.182 (No.3), pp. 1305-1313
- Tan, Bee K., Adya, Raghu, Chen, Jing, Farhatullah, Syed, Heutling, Dennis, Mitchell, Daniel A., Lehnert, Hendrik, Randeva, Harpal S., 2009. Metformin decreases angiogenesis via NF-kappa B and Erk1/2/Erk5 pathways by increasing the antiangiogenic thrombospondin-1. Cardiovascular Research, Vol.83 (No.3), pp. 566-574
- Färber, Katrin, Cheung, Giselle, Mitchell, Daniel A., Wallis, Russell, Weihe, Eberhard, Schwaeble, Wilhelm J., Kettenmann, Helmut, 2009. C1q, the recognition subcomponent of the classical pathway of complement, drives microglial activation. Journal of Neuroscience Research, Vol.87 (No.3), pp. 644-652
- Krarup, Anders, Mitchell, Daniel A., Sim, Robert B., 2008. Recognition of acetylated oligosaccharides by human L-ficolin. Immunology Letters, Vol.118 (No.2), pp. 152-156
- Krishnan, Nithya S., Fleetwood, Paul, Higgins, Rob, Hathaway, M. (Mark), Zehnder, Daniel, Mitchell, Daniel A., Hamer, Rizwan, Fletcher, S. (Simon), Lam, For Tai, Kashi, Habib, Tan, Lam Chin, Imray, C. (Chris), Briggs, D. (David), 2008. Application of flow cytometry to monitor antibody levels in ABO incompatible kidney transplantation. Transplantation, Vol.86 (No.3), pp. 474-477
- Mitchell, Daniel A., Ilyas, Rebecca, Dodds, Alister W., Sim, Robert B., 2008. Enzyme-independent, orientation-selective conjugation of whole human complement C3 to protein surfaces. Journal of Immunological Methods, Vol.337 (No.1), pp. 49-54
- Gaiha, Gaurav D., Dong, T., Palaniyar, Nades, Mitchell, Daniel A., Reid, Kenneth B. M., Clark, H. W., 2008. Surfactant protein A binds to HIV and inhibits direct infection of CD4(+) cells, but enhances dendritic cell-mediated viral transfer. Journal of Immunology, 181 (1), pp. 601-609
- Mitchell, Daniel A., Jones, Nigel A., Hunter, Stuart J., Cook, Joseph M. D., Jenkinson, Sarah F., Wormald, Mark R., Dwek, Raymond A., Fleet, George W. J., 2007. Synthesis of 2-C-branched derivatives of D-mannose: 2-C-aminomethyl-D-mannose binds to the human C-type lectin DC-SIGN with affinity greater than an order of magnitude compared to that of D-mannose. Tetrahedron: Asymmetry, Vol.18 (No.12), pp. 1502-1510
- Geng, Jin, Mantovani, Giuseppe, Tao, Lei, Nicolas, Julien, Chen, Gaojian, Wallis, Russell, Mitchell, Daniel A., Johnson, Benjamin R. G., Evans, Stephen D., Haddleton, David M., 2007. Site-directed conjugation of "Clicked" glycopolymers to form glycoprotein mimics: Binding to mammalian lectin and induction of immunological function. Journal of the American Chemical Society, Vol.129 (No.49), pp. 15156-15163
- Zhang, Qiang, Collins, Jennifer, Anastasaki, Athina, Wallis, Russell, Mitchell, Daniel A., Becer, C. Remzi, Wilson, Paul, Haddleton, David M., 2014. Sequence-controlled multi-block glycopolymers via cu(0) mediated living radical polymerization. In Lutz, Jean-Francois (ed.), Sequence-controlled polymers : synthesis, self-assembly, and properties, Washington DC, American Chemical Society, pp. 327-348
- Shaikhina, Torgyn, Khovanova, N. A., Daga, Sunil, Krishnan, Nithya, Lowe, David Philip, Mitchell, Daniel A., Briggs, David, Higgins, Rob, 2015. Decision trees for small data sets : prediction of acute antibody mediated rejection in early post-transplant period in antibody incompatible transplantation. Joint British Transplantation Society and Nederlandse Transplantatie Vereniging Congress, Bournemouth, UK, 11th - 13th Mar 2015
- Shaikhina, Torgyn, Khovanova, N. A., Daga, Sunil, Krishnan, Nithya, Lowe, David Philip, Mitchell, Daniel A., Briggs, David, Higgins, Rob, 2015. Prediction of acute antibody mediated rejection in antibody incompatible renal transplantation using machine learning for wide data. 2015 American Transplant Congress, Philadelphia, USA, 2 - 6 May 2015, Published in American Journal Transplant
- Khovanova, N. A., Lowe, David Philip, Daga, Sunil, Shaikhina, Torgyn, Mitchell, Daniel A., Zehnder, Daniel, Briggs, David, Higgins, Rob, 2015. Assessment of IgG subclass significance for early graft rejection and long-term survival in HLA-antibody incompatible renal transplantation : multivariate approach. 2015 American Transplant Congress, Philadelphia, USA, 2 - 6 May 2015, Published in American Journal Transplant
- Khovanova, N. A., Lowe, David Philip, Daga, Sunil, Shaikhina, Torgyn, Krishnan, Nithya, Mitchell, Daniel A., Zehnder, Daniel, Briggs, David, Higgins, Rob, 2015. IgG4 subclass associates with early graft rejection and decreased allograft survival times in antibody incompatible transplantation. Joint British Transplantation Society and Nederlandse Transplantatie Vereniging Congress, Bournemouth, UK, 11- 13 Mar 2015
- Shaikhina, Torgyn, Daga, Sunil, Krishnan, Nithya, Lowe, David Philip, Mitchell, Daniel A., Briggs, David, Higgins, Rob, Khovanova, N. A., 2014. Decision trees in renal transplantation : prediction of acute antibody mediated rejection in the early post-transplant period. Third International Transplantation conference : how much risk can you take (and what to do if it all goes pear shaped), University of Warwick, UK, 31 Oct - 01 Nov 2014
- Moyse, Harry, Lowe, David Philip, Briggs, D., Higgins, Rob, Bentall, A., Ball, S., Mitchell, Daniel A., Chappell, M. J. (Michael J.), Zehnder, Daniel, Evans, Neil D., 2012. Estimation of antibody binding affinities with surface plasmon resonance experiments in incompatible blood type renal transplants. 8th IFAC Symposium on Biological and Medical Systems, Budapest, Hungary, 29-31 Aug 2012, Published in Biological and Medical Systems, pp. 97-102
- Slavin, Stacy, Voorhaar, Lenny, Mitchell, Daniel A., Ilyas, Rebecca, Gibson, Matthew I., Haddleton, David M., Becer, C. Remzi, 2011. Synthesis of well-defined glycopolymers in various architectures and their interactions with DC-SIGN. 242nd National Meeting of the American-Chemical-Society (ACS), Denver, CO, 28 Aug - 1 Sep 2011, Published in American Chemical Society. Abstracts of Papers (at the National Meeting), pp. 545-POLY
- Hamer, Rizwan, Mitchell, Daniel A., Molostvov, G., Briggs, David, Mathieson, Peter, Satchell, Simon, Zehnder, Daniel, Higgins, Rob, 2009. Systemic and local complement systems in antibody-incompatible transplantation. American Transplant Congress 2009, Boston, MA, May 30-June 03, 2009, Published in American Journal of Transplantation, pp. 622-622
- Hamer, Rizwan, Mitchell, Daniel A., Fletcher, Simon, Briggs, David, Zehnder, Daniel, Krishnan, Nithya, Chen, Klaus, Higgins, Rob, 2009. Complement C5 inhibitor - is it useful in antibody-mediated rejection?. American Transplant Congress 2009, Boston, MA, May 30-June 03, 2009, Published in American Journal of Transplantation, pp. 410-410
- Geng, Jin, Mantovani, Giuseppe, Tao, Lei, Mitchell, Daniel A., Haddleton, David M., 2007. PMSE 456-Chain-folding via intramolecular crystal nucleation: Theory and simulations. Abstracts of papers of the American Chemical Society
- Krarup, Anders, Girija, Umakhanth Venkatraman, Mitchell, Daniel A., Smith, David F., Sim, Robert B., 2007. Investigation of L-ficolin binding specificity. 11th European Meeting on Complement in Human Disease, Cardiff, Wales, September 08-11, 2007, Published in Molecular Immunology, pp. 3959-3959
- Sim, Robert B., Kishore, Uday, Villiers, Christian L., Marche, Patrice N., Mitchell, Daniel A., 2007. C1q binding and complement activation by prions and amyloids. 6th International Workshop on the First Component of Complement C1 and Collectins, Seeheim, Germany, Jun 2006, Published in Immunobiology, pp. 355-362
- Mitchell, Daniel A., Fayter, Alice, Deller, Robert C., Hasan, Muhammad, Gutierrez-Marcos, José F., Gibson, Matthew I., 2019. Data for Ice-recrystallization inhibiting polymers protect proteins against freeze-stress and enable glycerol-free cryostorage. Materials Horizons, University of Warwick / Royal Society of Chemistry (RSC)
- 'Zhang, Yan, 'Briggs, David, 'Lowe, David Philip, 'Mitchell, Daniel A., 'Daga, Sunil, 'Krishnan, Nithya, 'Higgins, Rob, 'Khovanova, N. A., 2016. 'Data for A new data-driven model for post-transplant antibody dynamics in high risk kidney transplantation. University of Warwick, School of Engineering
- Marsh, Andrew, Casey-Green, Katherine, Probert, Fay, Withall, David M., Mitchell, Daniel A., Dilly , Suzanne J., James, Sean G., Dimitri, Wade, Ladwa, Sweta R. L., Taylor, Paul C., Singer, Donald R. J., 2015. Data for Simvastatin sodium salt and fluvastatin interact with human gap junction gamma-3 protein. University of Warwick, Department of Chemistry
- Higgins, Rob, Mitchell, Daniel A., 2009. Mannose-binding lectin ; the sugary-sticky side of transplantation. Transplantation, Lippincott Williams & Wilkins, pp. 149-150
| Title | Funder | Award start | Award end |
|---|---|---|---|
| Functional and biophysical characterisation of anti-HLA antibodies in renal transport rejection | University Hospitals Coventry and Warwickshire NHS Trust | 05 Oct 2015 | 04 Oct 2019 |
| Investigating the role of PAPP-A1 and DC-SIGN in Vascular Damage | Coventry General Charities | 01 Jan 2015 | 11 Jan 2019 |
| Conformational kinetic and thermodynamic analysis of glycan binding to DC-SIGN | University of Georgia | 08 Sept 2011 | 08 Sept 2013 |
| NIHR Doctoral Research Fellowship - David Lowe: Characterisation of Immunological Risk in antibody incompatible Transplantation. | National Institute for Health Research (DoH) | 01 Sept 2010 | 31 Aug 2013 |
| Quantitative Analysis of Immunoglobulin-Antigen Binding Affinity in ABO Incompatible Transplantation Via Surface Plasmon Resonance Spectroscopy. | National Health Service | 08 Oct 2010 | 07 Oct 2011 |