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Dr Daniel Mitchell

Job Title
Associate Professor (Teaching Focussed)
WMS - Biomedical Sciences
Research Interests

Research interests include the molecular basis for immune system interactions with their environments, especially the role of glycobiology and the complement system in pathogen recognition and cellular communication in host tissues. Recent work involves the analysis of polymer-protein and polymer-cell interactions in healthcare, drawing upon strengths in polymer chemistry at Warwick. These studies are being developed alongside clinical studies in renal transplantation at the University Hospital, Coventry.


Dan's research carried out as part of the PhD degree (awarded in 2000 from Imperial College) involved the genetics of autoimmune disease and the role of innate immune mechanisms in autoimmunity and inflammation. This work was carried out with Marina Botto and Mark Walport. Postdoctoral work at the Oxford Glycobiology Institute with Kurt Drickamer involved the post-genomic study of protein-oligosaccharide interactions within the immune system, especially those encountered in HIV infection. Subsequent work with Bob Sim at the MRC Immunochemistry Unit in Oxford involved the investigation of the immune system in prion diseases such as scrapie and BSE. Several significant publications have emerged from these collective studies, including papers in Science and Nature Medicine.

Title Funder Award start Award end
Functional and biophysical characterisation of anti-HLA antibodies in renal transport rejection University Hospitals Coventry and Warwickshire NHS Trust 05 Oct 2015 04 Oct 2019
Investigating the role of PAPP-A1 and DC-SIGN in Vascular Damage Coventry General Charities 01 Jan 2015 11 Jan 2019
Conformational kinetic and thermodynamic analysis of glycan binding to DC-SIGN University of Georgia 08 Sep 2011 08 Sep 2013
NIHR Doctoral Research Fellowship - David Lowe: Characterisation of Immunological Risk in antibody incompatible Transplantation. National Institute for Health Research (DoH) 01 Sep 2010 31 Aug 2013
Quantitative Analysis of Immunoglobulin-Antigen Binding Affinity in ABO Incompatible Transplantation Via Surface Plasmon Resonance Spectroscopy. National Health Service 08 Oct 2010 07 Oct 2011