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Dr Paul Squires

Job Title
Associate Professor (Reader)
Life Sciences
Web Link
Research Interests

1992-1995 Wellcome Trust Research Fellow, University of Sheffield, UK<br>1995-1996 Royal Society Traveling Research Fellow, UBC,Vancouver, Canada<br>1996-1997 Izaak Walton Killam Research Fellow, UBC, Vancouver, Canada<br>1997-2001 Diabetes UK, RD Lawrence Research Fellow, King's College London<br>1998 EASD/Bayer & Peter Baker Traveling Research Fellow, Uppsala, Sweden<br>2001-2005 Lecturer in Cellular Signalling, University of Warwick, UK<br>2001-2004 Honorary Lecturer, King's College London <br>2005-2010 Senior Lecturer Molecular Physiology, University of Warwick, UK<br>2010-present Reader in Diabetes & Endocrinology, University of Warwick, UK<br><br><br>My Research interests include elucidating sub-cellular mechanism that regulate insulin insulin secretion and action. A common avenue for both projects is the role of cell-to-cell communication in synchronising Ca2+-transients and function between cells of both the nephron and pancreatic islet.<br><p><b>Research Theme: <a href="">Cell Biology</a></b>


I joined the University of Warwick in 2001 following an RD Lawrence Research Fellowship (Diabetes UK:1998-2001) tenured at King's College London. I was awarded an Honorary Lectureship in the School of Biomedical Sciences KCL (2001-2004) and I was a recipient of the Paul Langerhans Research Fellowship for Research on the Physiology and Pathophysiology of the pancreatic beta-cell (EASD: 2001). I spent 3years at the University of British Columbia (UBC), Vancouver as a Royal Society Travelling Research Fellow and Honorary Fellow of the Izaak Walton Killam Memorial Foundation (1995-1998), and received a Travelling Research Fellowship to study at the University of Uppsala, Sweden (EASD/Bayer & Peter Baker). I'm currently Associate Professor (READER) within the School of Life Sciences and help deliver numerous modules, including: Molecular Endocrinology (BS252), Pharmacology (BS261) and Physiology & Metabolism (BS129). I have been External Assessor for the MSc Programme in Biomedicine & Molecular Science Research, KCL (2005-2009) and been involved in the recent Periodic Reviews for the Peninsula College of Medicine and Dentistry Graduate program (2012). I have been a member of the Research Advisory Boards for Diabetes UK (DUK: 2005-2012), the Diabetes Research & Wellness Foundation (DRWF: 2010-present) and the European Foundation for the Study of Diabetes (EFSD: 2012-present) and I am the Warwick representative to the Physiological Society (2009-present).

Title Funder Award start Award end
Special K and urological complications of ketamine abuse The Teresa Rosenbaum Golden Charitable Trust (Rosetrees Trust) 01 Oct 2013 30 Sep 2016
Does reorganisation of the extracellular matrix promote a loss of phenotypic stability in diabetic nephropathy? WPH Charitable Trust 01 Mar 2014 29 Feb 2016
DUK Equipment Grant: AFM single-cell force spectroscopy: determining the functional role of cell-cell adhesion and membrane dynamics in diabetes Diabetes UK 01 Jan 2013 31 Dec 2015
The effect of TGF-beta on connexin-mediated signalling: a role in diabetic nephropathy. Diabetes UK 01 Oct 2011 30 Sep 2014
The importance of cell-to-cell contact in diabetic nephropathy: identifying potential novel targets for therapeutic intervention WPH Charitable Trust 01 Mar 2012 28 Feb 2014
The effect of TGF-beta on cell adhesion, cell coupling & cell communication: a role in diabetic nephropathy European Foundation for the Study of Diabetes (EFSD) 01 Oct 2011 31 May 2013
A role for C-peptide in alleviating diabetic nephropathy Diabetes Research and Wellness Foundation 01 Feb 2010 31 Jan 2011
The extracellular calcuim-sensing receptor and paracrine signalling in the islet Diabetes UK 01 Dec 2009 30 Nov 2010
Royal Society Conference Grant (42nd Annual Conference of EASD, Copenhagen) Royal Society 13 Sep 2006 17 Sep 2006
41st Annual Meeting of the European Association for the Study of Diabetes Royal Society 10 Sep 2005 15 Sep 2005
Renal regulation of sodium transport by tubular osmotic variation: a potential role in the development of hypertension asociated with Diabetes Mellitus Diabetes Endocrine and Immersion Research Trust 01 Jun 2003 31 May 2005
Regulation of sodium transport in ocular ciliary epithelium; a role in the development of diabetic glaucoma Diabetes Endocrine and Immersion Research Trust 01 May 2004 30 Apr 2005