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Clinical Trials Design and Delivery


Medical files

WMS is home to the Warwick Clinical Trials Unit, an academic unit undertaking clinical trials addressing real issues of local, national and international importance.

Multi-centre, randomised controlled trials are run in close collaboration with local NHS Trusts and clinicians. Trials are subjected to rigorous external peer review and efficiently managed, to ensure high quality results.

The main areas of research are:

  • Emergency, critical care and rehabilitation trials
  • Cancer trials
  • Clinical trials methodology
  • Systematic reviews

WMS takes an interdisciplinary approach to clinical trials, with collaboration between clinical trialists, statisticians, Health Economists, clinical experts and project managers. The programmes of work draw together quantitative and qualitative methodologies in an evaluation framework.


Current research:

    Current trials include:
    • Wound management of Open Lower Limb Fractures
    • Dementia and Physical Activity
    • Protocolised trial of invasive and non-invasive weaning off ventilation
    • Strengthening And Stretching in Rheumatoid Arthritis of the Hand
    • Optimal Personalised Treatment of breast cancer usIng Multi-parameter Analysis: preliminary study
    • Determination of Epidermal growth factor receptor inhibitor (cetuximab) versus Standard Chemotherapy (cisplatin) early And Late Toxicity Events in Human Papillomavirus positive oropharyngeal squamous cell carcinoma
    • Avastin Randomised Trial with neo-adjuvant chemotherapy for patients with early breast cancer
    • Warwick Hip Trauma Evaluation Study

    Further details of these, and additional trials, can be found on the Clinical Trials Unit website

    Issues:

    Issues addressed by clinical trials research at WMS include:
    • Health issues of local and national importance
    • Emergency, critical care and rehabilitation
    • Cancer
    • Methodology and systematic reviews

    Funding:

    We receive funding from the following sources:
    • NIHR HTA programme
    • Cancer Research UK
    • British Heart Foundation
    • Resuscitation Council (UK)