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Research by Clinical Area: Trauma and Orthopaedics

BOOSTBOOST

Better Outcomes for Older people with Spinal Trouble

The BOOST trial is studying the physiotherapy treatment of back and leg pain or symptoms due to lumbar spinal stenosis (also called neurogenic claudication). This is a condition that affects older people and limits their ability to walk and stand which impacts on their ability to remain independent. Please visit these pages for more information.

HE: Stavros Petrou, Benjamin Parker Funder: NIHR PGfAR

FASHIONfashion

UK Full Randomised Controlled Trial of Arthroscopic Surgery for Hip Impingement versus best coNventional care

The FASHIoN study is a multicentre randomised controlled trial comparing the clinical and cost effectiveness of arthroscopy surgery versus best conservative care for patients with femoroacetabular impingement syndrome. Please find more information on this study here.

HE: Stavros Petrou, Felix Achana PI: Damian Griffin Funder: NIHR HTA

FIXDTfixdt

UK Fixation of Distal Tibia Fractures Trial is a randomised controlled trial comparing intramedullary nail fixation with locking plate fixation for patients with a distal tibia fracture.

The treatment of fractures of the lower third of the tibia remains controversial. These injuries are difficult to manage because the blood supply to the skin over the bone is poor and because the proximity of the fracture to the ankle joint. Infections and problems of bone healing are well recognised complications. Most of these injuries require surgery. The most common methods of fixation are: intramedullary nail fixation and locking plate fixation. At present, there is limited evidence as to which technique is better with regards to healing of the bone, ankle function and quality of life. Multi-centre randomised controlled trial where participants will be randomised on a 1:1 basis, stratified by trial centre and participant age. The target recruitment is 320 patients and patients will be followed up at 6 weeks, 3 months, 6 months and 12 months post operatively. Please find more information on the study here.

HE: Stavros Petrou, Mandy Maredza PI: Matthew Costa Funder: NIHR HTA

STARSTAR

UKSTAR: UK Study of Tendo Achilles Rehabilitation

The UK Study of tendo Achilles Rehabilitation is a multicentre randomised clinical trial sponsored by the University of Oxford. The trial is comparing the plaster cast versus walking boot treatment for non-operatively managed Achilles tendon ruptures and is funded by Health Technology Assessment - National Institute of Health Research. As a potential patient you can find more information relating to your treatment, download our Patient Information Sheet and contact the UKSTAR Trial Team if you have any questions. If you are an investigator or involved in the trial's research team you can navigate ‘For the Research Team’ pages for further information relating to the UKSTAR trial. Please visit these pages for more information on this study.

HE: Stavros Petrou PI: Matthew Costa Funder: NIHR HTA

WHISTWHIST

Wound healing in Surgery for Trauma

Wound Healing In Surgery for Trauma is a Randomised Controlled Trial of standard wound management versus negative pressure wound therapy in the treatment of adult patients having surgical incisions for major trauma to the lower limb. Please find the study's website here.

HE: Jason Madan PI: Matthew Costa Funder: NIHR EME

WOLLFWOLLF

Wound Management of Open Lower Limb Fractures

A randomised controlled trial of standard care wound management versus negative pressure wound therapy in the treatment of adult patients with an open fracture of the lower limb. Please find more information on the study here.

HE: Stavros Petrou, Benjamin Parker