Evidence synthesis. Survival analysis.
Martin Connock joined Warwick Evidence within the Warwick Medical School in April 2011 as a Systematic Reviewer (Senior Research Fellow). He graduated in Zoology with first class degree from the University of Wales in 1964 and gained an MSc in Radiobiology from the University of Birmingham in 1965, and PhD in Biochemistry from the University of Birmingham in 1968. After 3 years work as a post-doctoral researcher he taught Biochemistry at the University of Wolverhampton until 2000. He then completed an MSc in Health Technology Assessment at the University of Birmingham in 2003 and continued work in Birmingham's department of Public Health and Epidemiology until 2011 gaining experience in undertaking systematic reviews in Health Technology Assessments (HTAs) for the National Institute for Health and Clinical Excellence (NICE) and the National Institute for Health Research (NIHR) HTA programme. His current responsibility is to undertake technology appraisal reviews (TARs) commissioned by NICE.
- 'Connock, Martin, 'Auguste, Peter, 'Armoiry, Xavier, 2021. 'A comparison of published time invariant Markov models with Partitioned Survival models for cost effectiveness estimation; three case studies of treatments for glioblastoma multiforme. The European Journal of Health Economics, 22 (1), pp. 89-100
- Connock, Martin, Andronis, Lazaros, Auguste, Peter, Dussart, Claude, Armoiry, Xavier, 2020. Will the US$5 million onasemnogene abeparvosec treatment for spinal muscular atrophy represent ?value for money' for the NHS? A rapid inquiry into suggestions that it may be cost-effective. Expert Opinion on Biological Therapy, 20 (7), pp. 823-827
- Armoiry, Xavier, Cummins, Ewen, Connock, M., Metcalfe, Andrew J., Royle, Pamela, Johnston, Rhona, Rodrigues, Jeremy, Waugh, Norman, Mistry, Hema, 2019. Autologous chondrocyte implantation with chondrosphere for treating articular cartilage defects in the knee : an evidence review group perspective of a NICE single technology appraisal. PharmacoEconomics, 37, pp. 879-886
- Mistry, Hema, Nduka, Chidozie U., Connock, Martin, Colquitt, Jill, Mantopoulos, Theodoros, Loveman, Emma, Walewska, Renata, Mason, James, 2019. Correction to: Venetoclax for Treating Chronic Lymphocytic Leukaemia: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. PharmacoEconomics, 37 (6), pp. 869-869
- Armoiry, Xavier, Connock, M., Tsertsvadze, Alexander, Cummins, Ewen, Melendez-Torres, G. J., Royle, Pamela, Clarke, Aileen, 2018. Ixazomib for relapsed or refractory multiple myeloma : review from an evidence review group on a NICE single technology appraisal. PharmacoEconomics, 36, pp. 1073-1081
- Mistry, Hema, Nduka, Chidozie U., Connock, M., Colquitt, Jill, Mantopoulos, Theodoros, Loveman, Emma, Walewska, Renata, Mason, James, 2017. Venetoclax for treating chronic lymphocytic leukaemia : an evidence review group perspective of a NICE single technology appraisal. PharmacoEconomics
- Freeman, Karoline, Taylor-Phillips, Sian, Connock, M., Court, Rachel A., Tsertsvadze, Alexander, Shyangdan, D. (Deepson), Auguste, Peter, Mistry, Hema, Arasaradnam, Ramesh P., Sutcliffe, P. (Paul), Clarke, Aileen, 2017. Test accuracy of drug and antibody assays for predicting response to anti-Tumour Necrosis Factor treatment in Crohn?s disease : a systematic review and meta-analysis. BMJ Open, 7
- Mistry, Hema, Connock, M., Pink, Joshua, Shyangdan, D. (Deepson), Clar, Christine, Royle, Pamela, Court, Rachel A., Biant, Leela C., Metcalfe, Andrew J., Waugh, Norman, 2017. Autologous chondrocyte implantation in the knee : systematic review and economic evaluation. Health Technology Assessment, 21 (6), pp. 1-294
- Pulikottil-Jacob, Ruth, Connock, M., Ngianga-Bakwin, Kandala, Mistry, Hema, Grove, Amy L., Freeman, Karoline, Costa, Matthew L., Sutcliffe, P. (Paul), Clarke, Aileen, 2016. Has metal-on-metal resurfacing been a cost-effective intervention for health care providers? - a registry based study. PLoS One, 11 (11)
- Freeman, Karoline, Connock, M., Auguste, Peter, Taylor-Phillips, Sian, Mistry, Hema, Shyangdan, D. (Deepson), Court, Rachel A., Arasaradnam, Ramesh P., Sutcliffe, P. (Paul), Clarke, Aileen, 2016. Clinical effectiveness and cost-effectiveness of use of therapeutic monitoring of tumour necrosis factor alpha (TNF-?) inhibitors [LISA-TRACKER® enzyme-linked immunosorbent assay (ELISA) kits, TNF-?-Blocker ELISA kits and Promonitor® ELISA kits] versus standard care in patients with Crohn?s disease: systematic reviews and economic modelling. Health Technology Assessment, 20 (83), pp. 1-288
- Freeman, Karoline, Saunders, Mark P., Uthman, Olalekan A., Taylor-Phillips, Sian, Connock, M., Court, Rachel A., Gurung, T., Sutcliffe, P. (Paul), Clarke, Aileen, 2016. Is monitoring of plasma 5-fluorouracil levels in metastatic / advanced colorectal cancer clinically effective? A systematic review. BMC Cancer, 16 (1)
- Kandala, Ngianga-Bakwin, Connock, M., Pulikottil-Jacob, Ruth, Sutcliffe, P. (Paul), Crowther, Michael, Grove, Amy L., Mistry, Hema, Clarke, Aileen, 2015. Setting benchmark revision rates for total hip replacement : analysis of registry evidence. BMJ (Clinical research ed.), 350
- Pulikottil-Jacob, Ruth, Connock, M., Kandala, Ngianga-Bakwin, Mistry, Hema, Grove, Amy L., Freeman, Karoline, Costa, Matthew L., Sutcliffe, P. (Paul), Clarke, Aileen, 2015. Cost effectiveness of total hip arthroplasty in osteoarthritis : comparison of devices with differing bearing surfaces and modes of fixation. Bone & Joint Research, 97 (4), pp. 449-457
- Freeman, Karoline, Connock, M., Cummins, Ewen, Gurung, Tara, Taylor-Phillips, Sian, Court, Rachel A., Saunders, Mark, Clarke, Aileen, Sutcliffe, P. (Paul), 2015. Fluorouracil plasma monitoring : systematic review and economic evaluation of the My5-FU assay for guiding dose adjustment in patients receiving fluorouracil chemotherapy by continuous infusion. Health Technology Assessment, 19 (91), pp. 1-322
- Clarke, Aileen, Pulikottil-Jacob, Ruth, Grove, Amy L., Freeman, Karoline, Mistry, Hema, Tsertsvadze, Alexander, Connock, M., Court, Rachel A., Kandala, Ngianga-Bakwin, Costa, Matthew L., Suri, Gaurav, Metcalfe, David, Crowther, Michael, Morrow, Sarah, Johnson, Samantha J., Sutcliffe, P. (Paul), 2015. Total hip replacement and surface replacement for the treatment of pain and disability resulting from end-stage arthritis of the hip (review of technology appraisal guidance 2 and 44) : systematic review and economic evaluation. Health Technology Assessment, 19 (10), pp. 1-668
- Kandala, Ngianga-Bakwin, Connock, M., Pulikottil-Jacob, Ruth, Mistry, Hema, Sutcliffe, P. (Paul), Costa, Matthew L., Clarke, Aileen, 2014. Response to two recent BMJ papers on mortality after hip replacement : a comparative modelling study. British Medical Journal, 348
- Pulikottil-Jacob, Ruth, Suri, Gaurav, Connock, M., Kandala, Ngianga-Bakwin, Sutcliffe, P. (Paul), Maheswaran, Hendramoorthy, Banner, Nicholas R., Clarke, Aileen, 2014. Comparative cost-effectiveness of the HeartWare versus HeartMate II left ventricular assist devices used in the United Kingdom National Health Service bridge-to-transplant program for patients with heart failure. The Journal of Heart and Lung Transplantation, 33 (4), pp. 350-358
- Clarke, Aileen, Pulikottil-Jacob, Ruth, Connock, M., Suri, G., Kandala, Ngianga-Bakwin, Maheswaran, Hendramoorthy, Banner, Nicholas R., Sutcliffe, P. (Paul), 2014. Cost-effectiveness of left ventricular assist devices (LVADs) for patients with advanced heart failure : analysis of the British NHS Bridge to Transplant (BTT) program. International Journal of Cardiology, 171 (3), pp. 338-345
- Clarke, Aileen, Pulikottil-Jacob, Ruth, Grove, Amy L., Freeman, Karoline, Mistry, Hema, Tsertsvadze, Alexander, Connock, M., Court, Rachel A., Kandala, Ngianga-Bakwin, Costa, Matthew L., Sutcliffe, P. (Paul), 2014. Hips : hip replacement interventions for osteoarthritis in the UK ? a clinical and cost-effectiveness analysis. Journal of Epidemiology & Community Health, 68 (1), pp. a37-a38
- Tsertsvadze, Alexander, Grove, Amy L., Freeman, Karoline, Court, Rachel A., Johnson, Samantha Ann, Connock, M., Clarke, Aileen, Sutcliffe, P. (Paul), 2014. Total hip replacement for the treatment of end stage arthritis of the hip : a systematic review and meta-analysis. PLoS One, 9 (7)
- Sutcliffe, P. (Paul), Connock, M., Gurung, T., Freeman, Karoline, Johnson, Samantha Ann, Kandala, Ngianga-Bakwin, Grove, Amy L., Gurung, Binu, Morrow, Sarah, Stranges, Saverio, Clarke, Aileen, 2013. Aspirin in primary prevention of cardiovascular disease and cancer : a systematic review of the balance of evidence from reviews of randomized trials. PLoS One, 8 (12)
- Clarke, Aileen, Pulikottil-Jacob, Ruth, Connock, M., Suri, G., Kandala, Ngianga-Bakwin, Maheswaran, Hendramoorthy, Banner, R., Sutcliffe, P. (Paul), 2013. Cost-effectiveness of new left ventricular assist devices (LVADS) for patients with advanced heart failure : analysis of the UK NHS bridge to transplant (BTT) programme. Journal of Epidemiology and Community Health, 67 (1)
- Sutcliffe, P. (Paul), Connock, M., Gurung, T., Freeman, Karoline, Johnson, Samantha Ann, Kandala, Ngianga-Bakwin, Grove, Amy L., Gurung, B., Morrow, S., Clarke, Aileen, 2013. Aspirin for prophylactic use in the primary prevention of cardiovascular disease and cancer : a systematic review and overview of reviews. Health Technology Assessment, 17 (43), pp. 1-253
- Sutcliffe, P. (Paul), Connock, M., Pulikottil-Jacob, Ruth, Kandala, Ngianga-Bakwin, Suri, G., Gurung, T., Grove, Amy L., Shyangdan, D., Briscoe, Simon, Maheswaran, Hendramoorthy, Clarke, Aileen, 2013. Clinical effectiveness and cost-effectiveness of second- and third-generation left ventricular assist devices as either bridge to transplant or alternative to transplant for adults eligible for heart transplantation : systematic review and cost-effectiveness model. Health Technology Assessment, 17 (53), pp. 1-500
- Sutcliffe, P. (Paul), Connock, M., Shyangdan, D., Court, Rachel A., Kandala, Ngianga-Bakwin, Clarke, Aileen, 2013. A systematic review of evidence on malignant spinal metastases : natural history and technologies for identifying patients at high risk of vertebral fracture and spinal cord compression. Health Technology Assessment, 17 (42)
- Kandala, Ngianga-Bakwin, Connock, M., Grove, Amy L., Sutcliffe, P. (Paul), Mohiuddin, Syed, Hartley, Louise, Court, Rachel A., Cummins, E., Gordon, Caroline, Clarke, Aileen, 2013. Belimumab : a technological advance for systemic lupus erythematosus patients? Report of a systematic review and meta-analysis. BMJ Open, 3 (7)
- Stradling, Clare, Chen, Y-F.??, Russell, Tracy, Connock, M., Thomas, G. Neil, Taheri, S., 2012. The effects of dietary intervention on HIV dyslipidaemia : a systematic review and meta-analysis. PLoS ONE, Vol.7 (No.6)
- Dretzke, J., Edlin, R., Round, J., Connock, M., Hulme, C., Czeczot, J., Fry-Smith, A., McCabe, C., Meads, C., 2011. A systematic review and economic evaluation of the use of tumour necrosis factor-alpha (TNF-a) inhibitors, adalimumab and infliximab, for Crohn's disease. Health Technology Assessment, 15 (6)
- Malottki, K., Barton, P., Tsourapas, A., Uthman, A. O., Liu, Z., Routh, K., Connock, M., Jobanputra, P., Moore, D., Fry-Smith, A., Chen, Y-F.??, 2011. Adalimumab, etanercept, infliximab, rituximab and abatacept for the treatment of rheumatoid arthritis after the failure of a tumour necrosis factor inhibitor: a systematic review and economic evaluation. Health Technology Assessment, 15 (14)
- Dretzke, J., Edlin, R., Round, J., Connock, M., Hulme, C., Czeczot, J., Fry-Smith, A., McCabe, Chris, Meads, C., 2011. A systematic review and economic evaluation of the use of tumour necrosis factor-alpha (TNF-a) inhibitors, adalimumab and infliximab, for Crohn's disease. Health Technology Assessment, Vol.15 (No.6), pp. 1-244
- Malottki, K., Bartos, P., Tsourapas, A., Uthman, Olalekan A., Liu, Z., Routh, K., Connock, M., Jobanputra, P., Moore, D., Fry-Smith, A., Chen, Y-F.??, 2011. Adalimumab, etanercept, infliximab, rituximab and abatacept for the treatment of rheumatoid arthritis after the failure of a tumour necrosis factor inhibitor : a systematic review and economic evaluation. Health Technology Assessment, 15 (14), pp. 1-278
- Nouwen, A., Nefs, G., Caramlau, I., Connock, M., Winkley, K., Lloyd, C. E., Peyrot, M., Pouwer, F., 2011. Prevalence of depression in individuals with impaired glucose metabolism or undiagnosed diabetes : a systematic review and meta-analysis of the European Depression in Diabetes (EDID) Research Consortium. Diabetes Care, 34 (3), pp. 752-762
- Connock, M., Hyde, Chris, Moore, David, 2011. Cautions regarding the fitting and interpretation of survival curves. PharmacoEconomics, Vol.29 (No.10), pp. 827-837
- Moore, D., Aveyard, P., Connock, M., Wang, D., Fry-Smith, A., Barton, P., 2009. Effectiveness and safety of nicotine replacement therapy assisted reduction to stop smoking : systematic review and meta-analysis. BMJ, Vol.338
- Moore, David J., Dr., Adi, Y., Connock, M., Bayliss, Sue, 2009. Clinical effectiveness and cost-effectiveness of pegvisomant for the treatment of acromegaly: a systematic review and economic evaluation. BMC Endocrine Disorders, Vol.9 (Article 20)
- Wang, D., Connock, M., Barton, P., Fry-Smith, A., Aveyard, P., Moore, D., 2008. 'Cut down to quit' with nicotine replacement therapies in smoking cessation : a systematic review of effectiveness and economic analysis. Health Technology Assessment, Vol.12 (No.2), pp. iii-iv, ix
- 'Armoiry, Xavier, 'Connock, Martin, 2022. 'Correspondence on 'Cost-effectiveness of transcatheter edge-to-edge repair in secondary mitral regurgitation does need confirmation' by Cohen et al. Heart, B M J Group
- Armoiry, Xavier, Tsertsvadze, Alexander, Connock, Martin, Melendez-Torres, G.J., Clarke, Aileen, 2017. Systematic review and network meta-analysis of treatment outcomes for multiple myeloma. Journal of Clinical Oncology, American Society of Clinical Oncology, pp. 2975-2976
- Kandala, Ngianga-Bakwin, Connock, M., Pulikottil-Jacob, Ruth, Mistry, Hema, Sutcliffe, P. (Paul), Costa, Matthew L., Clarke, Aileen, 2014. Response to two recent BMJ papers on mortality after hip replacement : comparative modelling study. BMJ, BMJ Publishing Group Ltd
- Connock, M., Pulikottil-Jacob, Ruth, Mistry, Hema, Sutcliffe, P. (Paul), Costa, Matthew L., Clarke, Aileen, 2014. Re : Mortality rates at 10 years after metal-on-metal hip resurfacing compared with total hip replacement in England : retrospective cohort analysis of hospital episode statistics. British Medical Journal, BMJ Group
- Kandala, Ngianga-Bakwin, Connock, M., Pulikottil-Jacob, Ruth, Mistry, Hema, Sutcliffe, P. (Paul), Costa, Matthew L., Clarke, Aileen, 2014. Response to two recent BMJ papers on mortality of recipients of hip replacements. BMJ, BMJ Publishing Group Ltd
- Freeman, Karoline, Connock, M., Cummins, E., Gurung, T., Taylor-Phillips, Sian, Court, Rachel A., Saunders, Mark, Clarke, Aileen, Sutcliffe, P. (Paul), 2014. Diagnostic Assessment Report commissioned by the NIHR HTAProgramme on behalf of the National Institute for Health and CareExcellence ? Final report. Fluorouracil plasma monitoring : the My5-FU assay for guiding dose adjustment in patients receiving fluorouracil chemotherapy by continuous infusion. NICE, NICE (National Institute for Health and Care Excellence)
- Leslie, R., Todkill, Daniel, Mistry, Hema, Taylor-Phillips, Sian, Tsertsvadze, Alexander, Connock, M., Clarke, Aileen, 2013. Rapid literature review : would changing diabetic eye screening intervals from the current annual recommendation lead to changed clinical outcomes?. University of Warwick
- Connock, M., Cummins, E., Sutcliffe, P. (Paul), Court, Rachel A., Johnson, Rhona, Grove, Amy L., Kandala, Ngianga-Bakwin, Mohiuddin, Syed, Clarke, Aileen, 2011. Belimumab for the treatment of active autoantibody-positive systemic lupus erythematosus. National Institute for Health and Clinical Excellence (NICE)
- Malottki, Kinga, Barton, Pelham, Tsourapas, Angelos, Uthman, Abdulrahman, Liu, Zulian, Routh, Kristina, Connock, M., Jobanputra, Paresh, Moore, David, Fry-Smith, Anne, Chen, Y-F.??, 2010. Adalimumab, etanercept, infliximab, rituximab and abatacept for the treatment of rheumatoid arthritis after the failure of a TNF inhibitor: a systematic review and economic evaluation. NICE