Skip to main content

Dr Anne Straube



Associate Professor


WMS - Cell and Development Biology
University of Warwick
Tel: +44 (0)2476 151169

Research Interests

I want to understand the mechanochemical processes underlying directional cell migration and polarity. We focus on the mechanisms that generate specific microtubule arrays and study the dynamic interactions of microtubules with the cell cortex during cell shape changes and spindle positioning. We are using live-cell imaging and biochemical approaches paired with RNA interference and target protein mutagenesis to analyse structure-function relationships of motor proteins, structural MAPs and the +TIP complex.


After a Diploma in Biochemistry and Molecular Biology from the University of Hamburg, Germany, I joined the lab of Gero Steinberg at the Ludwig Maximilian University in Munich and later at the Max Planck Institute for Terrestrial Microbiology in Marburg. For my PhD project I studied the microtubule cytoskeleton in the fungus Ustilago maydis, concentrating in particular on the dynamic re-organisation of microtubules during the cell cycle and on intracellular transport by the molecular motors dynein and kinesin, which carry traffic along microtubules. I then moved as a Postdoctoral Fellow of the Emmy Noether programme of the German Science Foundation (DFG) to the Wellcome Trust Centre for Cell Biology in Edinburgh, where I worked with Andreas Merdes on the microtubule cytoskeleton in differentiating muscle cells. In 2007, after three years in Edinburgh, I started my own lab at the Marie Curie Research Institute (MCRI) in Oxted, Surrey. When the MCRI closed in 2010, I moved with my colleagues Rob Cross and Andrew McAinsh to the University of Warwick to found the Centre for Mechanochemical Cell Biology. I am a Lister Institute Research Prize Fellow, Associate Professor in Mechanochemical Cell Biology and the Director of the MSc in Interdisciplinary Biomedical Research.

Research Projects

View Current Projects        View All Projects


View All Publications

Post Graduate Supervision

  • Regulation of microtubule and actin dynamics by EB proteins
  • Modelling shape fluctuations during cell migration Date of Completion:2015
  • Kinesin control of podosome formation
  • Specificity of kinesin transport
  • Cellular functions of MAP4 in mitosis and muscle differentiation Date of Completion:2011
  • Regulation of microtubule assembly by mammalian EB proteins.

  • Update your user profile on Ideate