A UK-led international team of researchers has discovered elemental metallic copper and iron in the human brain for the first time.
Oxidative Addition of a Mechanically Entrapped C(sp)-C(sp) Bond to a Rhodium(I) Pincer Complex
By use of a macrocyclic phosphinite pincer ligand and bulky substrate substituents, researchers in the Chaplin group have demonstrated how the mechanical bond can be leveraged to promote the oxidative addition of an interlocked 1,3‐diyne to a rhodium(I) center. The resulting rhodium(III) bis(alkynyl) product can be trapped out by reaction with carbon monoxide or intercepted through irreversible reaction with dihydrogen, resulting in selective hydrogenolysis of the C−C σ‐bond.
HOT article in Angew. Chem. Int. Ed.
Chemistry World Today highlights Shipman Group Research into 'Synthetic strategy exploits fluxional nitrogen to deliver three chiral centres for the price of one'