News
Warwick students and staff co-author RSC teaching book on Stereochemistry
Written, reviewed and tested by students, for students! As part of the RSC's latest series of tutorial textbooks, a team of students and staff have co-authored textbooks on Stereochemistry and Contextual Maths in Chemistry.
Warwick students Caroline Akamune and Matthew Taylor and academics Andrew Clark and Russ Kitson teamed up with Leeds student Michael Lloyd and academics Nimesh Mistry and Paul Taylor to create a new stereochemistry textbook. What makes this book different is that it is co-authored with students to be in the 'student voice' making it more accessible to the undergraduate reader. It is also written so it can be used in conjunction with a molecular modelling kit, in-line with research that shows rotating and manipulating objects (e.g. molecular models) with your hands helps with grasping spatial cognition concepts in your head!
The RSC Chemistry Student Guides series editing team includes Warwick's own Julie Macpherson.
Strongest carbon-carbon single bond yields to macrocyclic Rh complex
Oxidative Addition of a Mechanically Entrapped C(sp)-C(sp) Bond to a Rhodium(I) Pincer Complex
By use of a macrocyclic phosphinite pincer ligand and bulky substrate substituents, researchers in the Chaplin group have demonstrated how the mechanical bond can be leveraged to promote the oxidative addition of an interlocked 1,3‐diyne to a rhodium(I) center. The resulting rhodium(III) bis(alkynyl) product can be trapped out by reaction with carbon monoxide or intercepted through irreversible reaction with dihydrogen, resulting in selective hydrogenolysis of the C−C σ‐bond.
HOT article in Angew. Chem. Int. Ed.
Dixon Group publishes first molecular description of VanS binding site within vancomycin antibiotic, offering potential in future therapeutic engineering
Resistance has emerged to vancomycin, a last-resort antibiotic for treatment of MRSA. The VanSR regulatory system induces expression of resistance genes upon exposure; however, the mechanism of vancomycin detection was unclear. Through solution NMR and other biophysical methods, we reveal a direct interaction between vancomycin and the extracellular domain of VanS from Streptomyces coelicolor. The VanS-binding epitope within vancomycin was mapped to a region distinct from the binding site for Lipid II. In targeting a separate site, the effective VanS ligand concentration includes both free and lipid-bound molecules, facilitating VanS activation. This is the first molecular description of the VanS/vancomycin interface, and could direct engineering of future therapeutics.
Bo Kelestyn shortlisted for Warwick Award for Teaching Excellence
We are proud of our Director of Student Experience Bo Kelestyn, who has been shortlisted for a Warwick Award for Teaching Excellence (WATE) which recognises outstanding teaching and support across the University. Bo has made a great impact since her arrival in Chemistry, we celebrate in her achievement of being shortlisted and wish her the very best of luck in winning the award.
Find out more about WATE.
BonLab takes the International Polymer Colloids Group online in exciting global weekly science webinar series
The International Polymer Colloid Group (IPCG) was founded in 1972 as a global forum for the exchange of ideas and emerging research activities for scientists and engineers from both academia and industry who study or use polymer colloids.
It is a vibrant scientific international community who normally meet face-to-face every two years to discuss the latest global developments related to polymer colloid science (2013 Shanghai, 2015 New Hampshire, 2017 the Basque Country, 2019 Singapore).
As a result of the global COVID19 pandemic, prof. dr. ir. Stefan Bon came up with the idea to take the IPCG forum online with a series of weekly scientific webinars, called the i-PCG 2020 Webinars. Anyone who is interested in science can participate as audience member, or even better, as presenter. Expect to interact with the world top in polymer colloid, with expert participants from industry, academia and enthusiasts. All is free.