Publications - 2007

• Structure and Mechanism of HpcH: A Metal Ion Dependent Class II Aldolase from the Homoprotocatechuate Degradation Pathway of Escherichia coli. D. Rea, V. Fueloep, T. D. H. Bugg, D. I. Roper, Journal of Molecular Biology (2007), 373(4), 866-876.
• Adenosine phosphonate inhibitors of lipid II: Alanyl tRNA ligase MurM from Streptococcus pneumoniae. E. Cressina, A. J. Lloyd, G. De Pascale, D. I. Roper, C. Dowson, T. D. H. Bugg, Bioorganic & Medicinal Chemistry Letters (2007), 17(16), 4654-4656.
• Investigation of a general base mechanism for ester hydrolysis in C-C hydrolase enzymes of the α/β-hydrolase superfamily: a novel mechanism for the serine catalytic triad. J.–J. Li, T. D. H. Bugg, Organic & Biomolecular Chemistry (2007), 5(3), 507-513.