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Fatal COVID-19 outcomes are associated with an antibody response targeting epitopes shared with endemic coronaviruses
One of the key questions relating to the COVID-19 pandemic is how prior immunity to related endemic coronaviruses affects the SARS-CoV-2 immune response. In this study, we provide evidence of immunological imprinting in individuals with fatal outcomes from COVID-19, suggesting an antibody profile consistent with an original antigenic sin type-response. Read the paper hereLink opens in a new window.