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The Institute of Precision Diagnostics and Translational Medicine at UHCW was delighted to welcome a nationwide audience to the launch of its Multi-Omics platform on Thursday 8 May 2025.

As clinical lead for the platform, Prof Dimitris Grammatopoulos, WMS Clinical Professor of Molecular Medicine, described the goals of the Platform, which were to deliver new biomarkers for precision medicine that would create a better understanding of disease pathways. Using Multi-Omics approaches, coupled with data science, the methodologies used will include targeted proteomics and spatial profiling, ensuring the region is at the cutting edge of diagnostics digitalisation in the UK. This capability will detect large sets of molecules including proteins at the spatial single-cell imaging level, which are suitable both for tissue and circulating cells research.

The Multi-Omics facility will enable specifically the development of detailed molecular maps in biopsies from multiple tissue types including, but not limited to liver, placenta and other reproductive tissues, various tumours, heart and blood cells coupled with blood biomarkers offering a complete characterisation of disease processes. Examples of programmes range from understanding the molecular basis of disease, through to novel diagnostics and treatments. This may include obesity and cardiometabolic disorders, liver disease, infectious disease, cancer, stroke, and neurodegeneration and feto-maternal disease, as well as embryo exposure to adverse intrauterine environment. Such granular data will aid both development – and selection of - appropriate treatments. Further, the capabilities of this facility will support research programmes and clinical trials in medical areas of national priority and relevance to the population of the West Midlands.

Users of the facility will be able to apply through Arden Tissue Bank for access to surplus to diagnosis human tissue samples from UHCW patients of relevant to the users’ research. The ethically approved regulatory compliant samples to be processed by the transcriptomics facility to provide an end-to-end research service.

Prof Gavin Perkins, Dean of Warwick Medical School, was delighted to be able to speak to the gathered audience, highlighting the importance of research to both UHCW and the University of Warwick and championing the Warwick Institute of Translational Medicine.

More details can be found here.

During the launch event Hannah Hooker, an MRCDTP PhD student supervised by Dimitris Grammatopoulos (WMS) and Natasha Khovanova (Engineering), presented her work on 'Multi-Omic Approaches to Improve Pre-eclampsia Prediction'. Hannah will present this work in the US Endocrine Society annual meeting 2025. Hannah has been selected to compete in the Rising Stars Power Talks competition, a research communication competition designated for early career and in-training members. Rising stars participants are selected based on top scoring ENDO abstracts.