Principal Investigators
Molecular mechanisms regulating eukaryotic cytokinesis
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The impact of human metabolism on development of obesity, and strategies to prevent and manage obesity and diabetes |
The molecular basis of obesity and diabetes |
The mechanisms of reproduction in mammals |
My main interest is focused on how eukaryotic DNA is packaged and organised within the cell |
Development of new tests and therapies to prevent implantation failure and miscarriage |
The force generating mechanisms of kinesins and microtubules |
The interplay between circadian clocks, diseases and pharmacotherapy |
Use cutting-edge techniques to explore the role of unconventional T cells in the immune surveillance of the human body |
Understanding flagellum function in protozoan parasites and humans |
Using biomaterials to address healthcare challenges, includes new materials inspired by antifreeze proteins for biologic storage; developing glycosylated nanomaterials |
Stress hormones and homeostatic adaptive responses in feto-maternal pathophysiology |
The Greaves lab are investigating disease mechanisms in the chronic inflammatory disorder endometriosis |
Indicators of oocyte and embryo development |
We want to understand how the cells of our immune system are capable of discriminating between healthy and infected cells |
The molecular and physical principles that govern processes at the plasma membrane of cells |
How cells ensure error-free chromosome segregation |
The fundamental mechanisms that regulate the cell division cycle |
The mechanism of cytokinesis |
Gene regulatory networks, regulatory sequence analysis, multi-omic and single-cell data analysis |
The development of novel materials for medical application |
Understanding and preventing pregnancy loss |
Metabolic and endocrine diseases, including obesity, diabetes and polycystic ovary syndrome in women, and their related heart problems |
How migrating cells talk to their immediate and distant neighbours using both chemical and mechanical signals |
Replication, detection and diagnosis of RNA viruses |
Mitosis and membrane trafficking
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Development and differentiation of embryonic progenitors and adult stem cells, and the molecular mechanisms underlying these processes |
Deciphering the biochemical and biomechanical processes that shape organs |
The crosstalk between cell and tissue-scale mechanics and biochemical signalling to regulate developmental programs and cellular mechanisms in the embryo |
Consultant pathologist at UHCW, research interests include improving early lung cancer diagnosis and the pathology of neuroendocrine lung tumours. Founding director of PathLAKE. |
Mechanisms by which neuroendocrine, autonomic and behavioural responses to disturbances in energy levels are integrated |
Mechanisms that generate specific microtubule arrays in polarised cells |
Viral evolution, pathogenesis and vaccine development |
Understanding how bacteria invade and survive our host defence systems |
Understanding the molecular mechanisms and ultimately exploiting natural bacterial toxin systems for biotechnology purposes
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Cancer pathogenesis and treatments
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The roles of key enzymes in the partitioning of fatty acid metabolism leading to oxidation or esterification |