Principal Investigators
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Molecular mechanisms regulating eukaryotic cytokinesis
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The impact of human metabolism on development of obesity and strategies to prevent and manage obesity and diabetes |
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The molecular basis of obesity and diabetes |
The mechanisms of reproduction in mammals |
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How eukaryotic DNA is packaged and organised within the cell |
The development of new tests and therapies to prevent implantation failure and miscarriage |
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The force generating mechanisms of kinesins and microtubules |
The interplay between circadian clocks, diseases and pharmacotherapy |
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The use of cutting-edge techniques to explore the role of unconventional T cells in the immune surveillance of the human body |
Cardiac arrhythmias; atrial fibrillation, ventricular tachycardia; ablation, complex mapping technologies |
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Understanding flagellum function in protozoan parasites and humans |
Stress hormones and homeostatic adaptive responses in feto-maternal pathophysiology |
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Investigating disease mechanisms in the chronic inflammatory disorder endometriosis |
Understanding the establishment and embryonic development of the mammalian germline. |
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Vascular surgery, pathophysiology of reperfusion injury in vascular surgery; vascular tissue engineering and regenerative medicine |
Indicators of oocyte and embryo development
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How the cells of our immune system are capable of discriminating between healthy and infected cells |
The molecular and physical principles that govern processes at the plasma membrane of cells |
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How the protozoan parasite Trypanosoma cruzi causes Chagas disease |
How cells ensure error-free chromosome segregation |
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Membrane organisation and dynamics at cellular interfaces |
The fundamental mechanisms that regulate the cell division cycle |
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The mechanism of cytokinesis |
Gene regulatory networks, regulatory sequence analysis, multi-omic and single-cell data analysis |
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The development of novel materials for medical application |
Understanding and preventing pregnancy loss |
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Metabolic and endocrine diseases, including obesity, diabetes and polycystic ovary syndrome in women, and their related heart problems |
How migrating cells talk to their immediate and distant neighbours using both chemical and mechanical signals |
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Replication, detection and diagnosis of RNA viruses |
Mitosis and membrane trafficking
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Development and differentiation of embryonic progenitors and adult stem cells, and the molecular mechanisms underlying these processes |
Deciphering the biochemical and biomechanical processes that shape organs |
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The crosstalk between cell and tissue-scale mechanics and biochemical signalling to regulate developmental programs and cellular mechanisms in the embryo |
Mechanisms by which neuroendocrine, autonomic and behavioural responses to disturbances in energy levels are integrated. |
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Mechanisms that generate specific microtubule arrays in polarised cells |
Viral evolution, pathogenesis and vaccine development |
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Understanding how bacteria invade and survive our host defence systems |
Understanding the molecular mechanisms and ultimately exploiting natural bacterial toxin systems for biotechnology purposes |
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Cancer pathogenesis and treatments
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The roles of key enzymes in the partitioning of fatty acid metabolism leading to oxidation or esterification
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Mohan Balasubramanian
Thomas Barber
Robert Dallmann
Shervanthi Homer-Vanniasinkam
Geraldine Hartshorne
Jonathan Millar
Masanori Mishima
Sascha Ott
Nicole Robb
Stephen Royle
Karuna Sampath
Timothy Saunders
Michael Smutny
Nick Waterfield
Lawrence Young
Victor Zammit