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Warwick Medical School

Recent Developments in the Patho-Physiological Molecular Clocks Lab

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Time to test for late clocks for early detection of gestational diabetes mellitus

Dr Robert DallmannLink opens in a new window and Prof Ponnusamy SaravananLink opens in a new window receive funding from the Gates FoundationLink opens in a new window for a project entitled "Molecular circadian biomarkers for early prediction of gestational diabetes mellitus (GDM)”
The aim of the project is to establish if circadian biomarkers can contribute to GDM risk-stratification in biosamples taken in early pregnancy. For this, we take advantage of a subsample of the well phenotyped PRiDE study, which included pregnant women from diverse ethnic backgrounds with and without GDM and, crucially, the associated clinical history. We will test their plasma, biobanked at George Eliot Hospital, Nuneaton, in a to be established bioassay using human fibroblasts and the TimeTeller algorithm as "circadian sensors”. Furthermore, once stratified by circadian phenotype, we aim to discover further correlative biomarkers that will allow to establish simple bioassays that will be easily available in LMICs, also a key aim of the foundation.
The project brings together the expertise of Warwick’s Chrono group, including the WMS based Dallmann lab and Rand’s group in Maths, as well as the WMS’ Saravanan who is also a clinically active Diabetes and Endocrinology specialist at George Eliot Hospital.
Mon 03 Nov 2025, 22:05 | Tags: Funding, 2025

Science on the Hill: Come see how Warwick tackles cancer with science

Free tickets for an evening on 11 November with talks and lots of time for engagement and discussion with chemists, physicists, mathematicians and computer scientists. Light refreshments are available.

Hear how mathematicians, statisticians, and computer scientists improve diagnosis and our understanding of cancer, how chemists take inspiration from fungi and bacteria to develop new anti-cancer drugs or design delivery vehicles that target immune cells, and physicists employ diamonds to look skin deep for cancer cells.

Whether you're curious about the equations that can guide diagnosis and improve therapy decisions or how magnets can help surgeons find cancer cells, this evening promises to inform and inspire.

Doors open at 5:30pm and light refreshments will be provided. Talks begin at 6:00pm.

Please note the recommended age for this event is 14+ and all under-18s must be accompanied by an adult.

Mon 27 Oct 2025, 18:06 | Tags: Outreach, 2025, Public Engagment

Chrono Lab goes LEAF

Thanks to the leadership of James Jarrold, the lab has achieved a LEAF Bronze Award.

LEAF Bronze

Tue 21 Oct 2025, 22:05 | Tags: 2025, LEAF

CIRCADIAN DISTRIBUTION OF VENTRICULAR ARRHYTHMIAS IN PATIENTS WITH STRUCTURAL HEART DISEASE AND THE IMPACT OF INVASIVE CATHETER ABLATION ON TIMINGS

As result of a reward collaboration between Tarv Dhanjal and the Chrono Group, SSC2 student Jawad Chowdhury is presenting his work on the timing of ventricular arrhythmias in heart disease patients at the Heart Rhythm Congress 2025 (05-07 October) in The International Convention Centre, Birmingham.

Tue 30 Sept 2025, 12:30 | Tags: Student, Conference, SSC2, 2025

Congratulations Dr Zhang!

Congratulations to Zijin Zhang who was funded by a CSC and worked on characterising novel oragnometalic drugs in a collaboration with Peter Sadler and the Chrono Group.

Fri 05 Sept 2025, 10:05 | Tags: PhD, viva, 2025

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