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James Mason





WMS - Population Evidence and Technologies
University of Warwick
Tel: 02476 151853
WebLink: Google Scholar

Research Interests

James is a Professor of Health Economics within Warwick Medical School. He works primarily with Warwick Evidence on NICE-funded HTA projects and for Warwick CTU on economic analysis of clinical trials.

Research interests are wide-ranging including economic analysis within clinical trials, economic models, cost-effectiveness of implementation, trial design, systematic review, epidemiological enquiry and evidence-based medicine.

Particular areas of experience include gastrointestinal, orthopedic and dermatological conditions. James serves as a methodologist on the NIHR HS&DR Board and the National Joint Registry Research Committee. He has previously served on the NIHR HTA themed commissioning panel and Programme Grants sub-panel.

James joined University of Warwick in 2015, moving from Durham University where he was co-director of RDS-NE and where he established Durham CTU. He is lead health economist on a number of studies including:

AIR: A UK study of ankle injury rehabilitation: multicentre randomised controlled trialNIHR CDF. CI: Rebecca Kearney, WCTU
ARTISAN: Acute Rehabilitation following Traumatic anterior shoulder dISlocAtioN: A Multi Centre RCT. NIHR HTA. PI: Rebecca Kearney, WCTU
CAPACITY: Developing of a UK Evidence-Based Pathway for the Management of Chronic Constipation in Adults. NIHR PGfAR Programme Grant. CI: Charles Knowles, PCTU.
FORCE: The Forearm Fracture Recovery in Children Evaluation: A multi-centre prospective randomized equivalence trial. NIHR HTA. CI Dan Perry, NDORMS
SCIENCE: Surgery or Cast for Injuries of the EpicoNdyle in Children's Elbows. A multi-centre prospective randomized superiority trial. NIHR HTA.CI James Wright, NDORMS
START:REACTS: Subacromial spacer for Tears Affecting Rotator cuff Tendons: a Randomised, Efficient, Adaptive Clinical Trial in Surgery. NIHR HTA.CI: Andrew Metcalfe, WCTU

James is a co-investigator for:

COSMIC: Colorectal cancer with Synchronous liver-limited Metastases: an Inception Cohort study of standardised care pathways. CI: Ajith Siriwardena
PROCAP: PROCalcitonin-based algorithm for antibiotic use in Acute Pancreatitis (PROCAP): A randomised controlled trial. CI: Ajith Siriwardena

James is also a co-applicant on:

DIAMAND-LEWY. Improving the diagnosis and management of dementias of lewy body type in the NHS. NIHR PGfAR Programme Grant. CI: John O'Brien.

Research Projects

View Current Projects        View All Projects


  • Mason, James, Chalmers, J. R., Godec, T., Nunn, A. J., Kirtschig, G., Wojnarowska, F., Childs, M., Whitham, D., Schmidt, E., Harman, K, Walton, S., Chapman, A., Williams, H. C., 2018. Doxycycline compared to prednisolone therapy for patients with bullous pemphigoid : cost-effectiveness analysis of the BLISTER trial. British Journal of Dermatology, 178 (2), pp. 415-423, View
  • Partridge, Thomas, Jameson, Simon, Baker, Paul, Deehan, David, Mason, James, Reed, Mike R., 2018. Ten-year trends in medical complications following 540,623 primary total hip replacements from a national database. The Journal of Bone and Joint Surgery (American), 100 (5), pp. 360-367, View
  • Williams, Hywel C., Wojnarowska, Fenella, Kirtschig, Gudula, Mason, James, Godec, Thomas R., Schmidt, Enno, Chalmers, Joanne R., Childs, Margaret, Walton, Shernaz, Harman, Karen, Chapman, Anna, Whitham, Diane, Nunn, Andrew J., 2017. Doxycycline versus prednisolone as an initial treatment strategy for bullous pemphigoid : a pragmatic, non-inferiority, randomised controlled trial. The Lancet, 389 (10079), pp. 1630-1638, View
  • Knowles, C. H., Grossi, U., Horrocks, E. J., Pares, D., Vollebregt, P. F., Chapman, M., Brown, S., Mercer-Jones, M., Williams, A. B., Yiannakou, Y., Hooper, R. J., Stevens, N., Mason, James, 2017. Surgery for constipation : systematic review and practice recommendations : Graded practice and future research recommendations. Colorectal Disease, 19 (S3), pp. 101-113, View
  • Dritsaki, Melina, Achana, Felix A., Mason, James, Petrou, Stavros, 2017. Methodological issues surrounding the use of baseline health-related quality of life data to inform trial-based economic evaluations of interventions within emergency and critical care settings : a systematic literature review. PharmacoEconomics, 35 (5), pp. 549-559, View
  • Cox, Julie, Hancock, Helen, Maier, Rebecca, Spratt, Jonathan, Lee, Chooi May, Bhatti, Amir, Mason, James, 2017. Multidetector CT improving surgical outcomes in breast cancer (MISO-BC) : a randomised controlled trial. The Breast, 32, pp. 217-224, View
  • Rees, Colin J., Rajasekhar, Praveen T., Wilson, Ana, Close, Helen, Rutter, Matthew D., Saunders, Brian P., East, James E., Maier, Rebecca, Moorghen, Morgan, Muhammad, Usman, Hancock, Helen, Jayaprakash, Anthoor, MacDonald, Chris, Ramadas, Arvind, Dhar, Anjan, Mason, James, 2017. Narrow band imaging optical diagnosis of small colorectal polyps in routine clinical practice : the Detect Inspect Characterise Resect and Discard 2 (DISCARD 2) study. Gut, 66, pp. 887-895, View
  • Freeman, Karoline, Tsertsvadze, Alexander, Taylor-Phillips, Sian, McCarthy, Noel D., Mistry, Hema, Manuel, Rohini, Mason, James, 2017. Agreement between gastrointestinal panel testing and standard microbiology methods for detecting pathogens in suspected infectious gastroenteritis : test evaluation and meta-analysis in the absence of a reference standard. PLoS One, 12 (3), View
  • Baltatzis, M., Chan, A. K. C., Jegatheeswaran, S., Mason, James, Siriwardena, A. K., 2016. Colorectal cancer with synchronous hepatic metastases : systematic review of reports comparing synchronous surgery with sequential bowel-first or liver-first approaches. European Journal of Surgical Oncology (EJSO), 42 (2), pp. 159-165, View
  • Adam, Z., Turley, Andrew, Mason, James, Kasim, A. S., Newby, David E., Mills, N., Padfield, G., Thompson, L., Morley, R., Wright, R. A., Hall, J. A., Muir, D. F., Sutton, A. G. C., Swanson, N., Carter, J., Bilous, R., Jones, S., de Belder, M. A., 2016. The SSTARS (STeroids and Stents Against Re-Stenosis) Trial : different stent alloys and the use of peri-procedural oral corticosteroids to prevent in-segment restenosis after percutaneous coronary intervention. International Journal of Cardiology, 216, pp. 1-8, View
  • Stinton, Chris, McKeith, Ian G., Taylor, John-Paul, Lafortune, Louise, Mioshi, Eneida, Mak, Elijah, Cambridge, Victoria, Mason, James, Thomas, Alan, O'Brien, John T., 2015. Pharmacological management of lewy body dementia : a systematic review and meta-analysis. American Journal of Psychiatry, 172 (8), pp. 731-742, View
  • Jameson, Simon S., Mason, James, Baker, Paul N., Gregg, Paul J., Deehan, David J., Reed, Mike R., 2015. Implant optimisation for primary hip replacement in patients over 60 years with osteoarthritis : a cohort study of clinical outcomes and implant costs using data from England and Wales. PLoS One, 10 (11), View
  • Miranda, Charles J., Mason, James, Babu, Benoy I., Sheen, Aali J., Eddleston, Jane M., Parker, Michael J., Pemberton, Philip, Siriwardena, Ajith K., 2015. Twenty-four hour infusion of human recombinant activated protein C (Xigris) early in severe acute pancreatitis: The XIG-AP 1 trial. Pancreatology, 15 (6), pp. 635-641, View
  • Emmett, Christopher D., Close, Helen J., Yiannakou, Yan, Mason, James, 2015. Trans-anal irrigation therapy to treat adult chronic functional constipation: systematic review and meta-analysis.. BMC Gastroenterology, 15, View
  • Ormerod, Anthony D., Thomas, Kim S., Craig, Fiona E., Mitchell, Eleanor, Greenlaw, Nicola, Norrie, John, Mason, James, Walton, Shernaz, Johnston, Graham A, Williams, Hywel C, 2015. Comparison of the two most commonly used treatments for pyoderma gangrenosum : results of the STOP GAP randomised controlled trial.. BMJ, 350, View
  • Harvey, Hannah, Reissland, Nadja, Mason, James, 2015. Parental reminder, recall and educational interventions to improve early childhood immunisation uptake: A systematic review and meta-analysis. Vaccine, 33 (25), pp. 2862-80, View
  • Cornford, Charles S., Close, Helen J., Bray, Roz, Beere, Deborah, Mason, James, 2015. Contraceptive use and pregnancy outcomes among opioid drug-using women : a retrospective cohort study.. PLoS One, 10 (3), View
  • Chalmers, J. R., Wojnarowska, F., Kirtschig, G., Nunn, A. J., Bratton, D. J., Mason, James, Foster, K. A., Whitham, D., Williams, H. C., 2015. A randomized controlled trial to compare the safety and effectiveness of doxycycline (200 mg daily) with oral prednisolone (0.5 mg kg(-1) daily) for initial treatment of bullous pemphigoid : a protocol for the Bullous Pemphigoid Steroids and Tetracyclines (BLISTER) trial. British Journal of Dermatology, 173 (1), pp. 227-34, View
  • Alshryda, S., Sukeik, M., Sarda, P., Blenkinsopp, J., Haddad, F. S., Mason, James, 2014. A systematic review and meta-analysis of the topical administration of tranexamic acid in total hip and knee replacement. The Bone & Joint Journal, 96-B (8), pp. 1005-1015, View
  • Siriwardena, Ajith K., Mason, James, Mullamitha, Saifee, Hancock, Helen C., Jegatheeswaran, Santhalingam, 2014. Management of colorectal cancer presenting with synchronous liver metastases. Nature Reviews Clinical Oncology, 11 (8), pp. 446-59, View
  • Close, Helen, Reilly, Joe, Mason, James, Kripalani, Mukesh, Wilson, Douglas, Main, John, Hungin, A Pali S., 2014. Renal failure in lithium-treated bipolar disorder : a retrospective cohort study. PLoS One, 9 (3), View
  • Mason, James, Thomas, Kim S., Crook, Angela M., Foster, Katharine A., Chalmers, Joanne R., Nunn, Andrew J., Williams, Hywel C., 2014. Prophylactic antibiotics to prevent cellulitis of the leg : economic analysis of the PATCH I & II trials. PLoS One, 9 (2), View
  • Warren, J., Bambra, C., Kasim, A., Garthwaite, K., Mason, James, Booth, M., 2014. Prospective pilot evaluation of the effectiveness and cost-utility of a 'health first' case management service for long-term Incapacity Benefit recipients. Journal of Public Health, 36 (1), pp. 117-25, View
  • Mason, Anne, Mason, James, Cork, Michael, Hancock, Helen, Dooley, Gordon, 2013. Topical treatments for chronic plaque psoriasis : an abridged Cochrane systematic review. Journal of the American Academy of Dermatology, 69 (5), pp. 799-807, View
  • Alshryda, Sattar, Mason, James, Sarda, Praveen, Nargol, Antoni, Cooke, Nick, Ahmad, Hafeez, Tang, S., Logishetty, Raj, Vaghela, Manesh, McPartlin, Lynne, Hungin, A Pali S., 2013. Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement : a randomized controlled trial (TRANX-H). The Journal of Bone and Joint Surgery, 95 (21), pp. 1969-1974, View
  • Alshryda, Sattar, Mason, James, Vaghela, Manesh, Sarda, Praveen, Nargol, Antoni, Maheswaran, S, Tulloch, Chris, Anand, Sanjeev, Logishetty, Raj, Stothart, Brian, Hungin, A Pali S., 2013. Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total knee replacement : a randomized controlled trial (TRANX-K). The Journal of Bone and Joint Surgery, 95 (21), pp. 1961-1968, View
  • Reissland, Nadja, Francis, Brian, Mason, James, 2013. Can healthy fetuses show facial expressions of "pain" or "distress"?. PLoS One, 8 (6), View
  • Thomas, Kim S., Crook, Angela M., Nunn, Andrew J., Foster, Katharine A., Mason, James, Chalmers, Joanne R., Nasr, Ibrahim S., Brindle, Richard J., English, John, Meredith, Sarah K., Reynolds, Nicholas J., de Berker, David, Mortimer, Peter S., Williams, Hywel C., 2013. Penicillin to prevent recurrent leg cellulitis. The New England Journal of Medicine, 368 (18), pp. 1695-1703, View
  • Jegatheeswaran, Santhalingam, Mason, James, Hancock, Helen C., Siriwardena, Ajith K., 2013. The liver-first approach to the management of colorectal cancer with synchronous hepatic metastases : a systematic review. JAMA surgery, 148 (4), pp. 385-91, View
  • Jameson, Simon S., Mason, James, Baker, Paul N., Jettoo, Prithee, Deehan, David J., Reed, Mike R., 2013. Factors influencing revision risk following 15 740 single-brand hybrid hip arthroplasties : a cohort study from a National Joint Registry. Journal of Arthroplasty, 28 (7), pp. 1152-1159.e1, View
  • Hancock, Helen C., Close, Helen, Mason, James, Murphy, Jerry J., Fuat, Ahmet, Singh, Raj, Wood, Esther, de Belder, Mark, Brennan, Gill, Hussain, Nehal, Kumar, Nitin, Wilson, Doug, Hungin, A Pali S., 2013. High prevalence of undetected heart failure in long-term care residents : findings from the Heart Failure in Care Homes (HFinCH) study. European Journal of Heart Failure, 15 (2), pp. 158-65, View
  • Mason, James, Hancock, Helen C., Close, Helen, Murphy, Jerry J., Fuat, Ahmet, de Belder, Mark, Singh, Raj, Teggert, Andrew, Wood, Esther, Brennan, Gill, Hussain, Nehal, Kumar, Nitin, Manshani, Novin, Hodges, David, Wilson, Douglas, Hungin, A Pali S., 2013. Utility of biomarkers in the differential diagnosis of heart failure in older people : findings from the heart failure in care homes (HFinCH) diagnostic accuracy study. PLoS One, 8 (1), View
  • Mason, Anne R., Mason, James, Cork, Michael, Dooley, Gordon, Hancock, Helen, 2013. Topical treatments for chronic plaque psoriasis. Cochrane Database of Systematic Reviews, 3, View

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