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James Mason

Job Title
Professor
Department
WMS - Warwick Clinical Trials Unit
Phone
02476 151853
Web Link
Research Interests

James is a Health Economist within Warwick Medical School, Director of the Centre for Health Economics at Warwick (CHEW) and an Associate Director within Warwick Clinical Trials Unit (WCTU). He works primarily on the economic analysis of clinical trials, epidemiological designs and statistical analyses.

Research interests are wide-ranging including methods for analysis within clinical trials, economic models, cost-effectiveness of implementation, trial design, systematic review, epidemiological enquiry and evidence-based medicine. Particular areas of experience include gastrointestinal, orthopedic and dermatological conditions.

James is a methodologist on the National Joint Registry Research Committee. He has previously served on the NIHR HS&DR Funding Committee, the HTA themed commissioning panel and Programme Grants sub-panel, as well as being a member of SaBTO (the government Advisory Committee for Safety in Blood Tissues and Organs).

He is co-investigator and lead health economist on a number of studies including:

AIRWAYS-3: Randomised trial of the clinical and cost effectiveness of a supraglottic airway device versus tracheal intubation during in-hospital cardiac arrest. NIHR HTA. CI: Jonathan Benger, WCTU

ARTISAN: Acute Rehabilitation following Traumatic anterior shoulder dISlocAtioN: A Multi Centre RCT. NIHR HTA. CI: Rebecca Kearney, WCTU

C-SPINE - Cervical spine immobilisation following blunt trauma. NIHR HTA. CI: Mark Wilson/Gavin Perkins, NDORMS.

CRAFFT: Children's Radius Acute Fracture Fixation Trial. NIHR HTA. CI: Dan Perry, NDORMS.

HUSH: The HUmeral SHaft fracture trial. NIHR HTA. CI Steve Gwilim, NDORMS

MeTeOR2 - The Meniscal Transplant surgery or Optimised Rehabilitation full randomised trial. NIHR HTA.CI: Andrew Metcalfe, WCTU

PARAMEDIC3: Pre-hospitAl Randomised triAl of MEDICation route in out-of-hosital cardiac arrest. NIHR HTA.CI: Gavin Perkins, WCTU

RACER: Robotic Arthroplasty: a Clinical and cost Effectiveness Randomised Controlled Trial. NIHR HTA.CI: Andrew Metcalfe, WCTU

REGAIN - Rehabilitation Exercise and psycholoGical support After covid-19 InfectioN.
NIHR HTA/Cross Programme. CI: Gordon Mcgregor, UHCW

SCIENCE: Surgery or Cast for Injuries of the EpicoNdyle in Children's Elbows. A multi-centre prospective randomized superiority trial. NIHR HTA.CI James Wright, NDORMS

SOS: Sugar or Salt trial: Hyperosmolar therapy in traumatic brain injury. NIHR HTA. CI: Gavin Perkins, WCTU

SPHERe: Supervised Pulmonary Hypertension Exercise Rehabilitation trial. NIHR HTA. CI: Gordon McGregor, WCTU

START:REACTS: Subacromial spacer for Tears Affecting Rotator cuff Tendons: a Randomised, Efficient, Adaptive Clinical Trial in Surgery. NIHR HTA.CI: Andrew Metcalfe, WCTU

VITAL:VolatIle vs Total intravenous Anaesthesia for major non-cardiac surgery ? a randomised controlled trial. NIHR HTA. CI: Joyce Yeung, WCTU

James is a also co-investigator for:

PROCAP: PROCalcitonin-based algorithm for antibiotic use in Acute Pancreatitis (PROCAP): A randomised controlled trial. CI: Ajith Siriwardena

ePAMS+: Development and evaluation of a complex ePrescribing-based Antimicrobial Stewardship: intervention for hospitals. NIHR PGfAR Programme Grant. CI: Aziz Sheikh.

Recently completed studies include:

AIR: A UK study of ankle injury rehabilitation: multicentre randomised controlled trial. NIHR CDF. CI: Rebecca Kearney, WCTU

CAPACITY: Developing of a UK Evidence-Based Pathway for the Management of Chronic Constipation in Adults. NIHR PGfAR Programme Grant. CI: Charles Knowles, PCTU.

COSMIC: Colorectal cancer with Synchronous liver-limited Metastases: an Inception Cohort study of standardised care pathways. CI: Ajith Siriwardena

DIAMAND-LEWY. Improving the diagnosis and management of dementias of lewy body type in the NHS. NIHR PGfAR Programme Grant. CI: John O'Brien.

FORCE: The Forearm Fracture Recovery in Children Evaluation: A multi-centre prospective randomized equivalence trial. NIHR HTA. CI Dan Perry, NDORMS

Title Funder Award start Award end
Second Stage NIHR HTA application: Robotic Arthroplasty: a Clinical and cost Effectiveness Randomised controlled trial for Hips (RACER-HIP): Outline IDEATE 65472. Main Trial: 67372. 2&5Y FU: IDEATE 67377. 10Y FU: IDEATE 67377 National Institute for Health Research (NIHR DoH) 01 Oct 2021 30 Sep 2033
Robotic Arthroplasty: a Clinical and cost Effectiveness Randomised controlled trial. (RACER) - NIHR HTA (second stage via UHCW NHS trust) RACCER (outline record 60354) Main Trial = 62365 (4yrs), Follow-on yrs 5-9 = 62408, and Follow-on yrs 10-13 = 62409 National Institute for Health Research (DoH) 01 Apr 2020 31 Mar 2033
NIHR HTA Stage 2: Personalised therapy or OpeRative Treatment? (REPPORT) National Institute for Health Research (NIHR DoH) 01 Jan 2023 31 Dec 2027
Stage 2 NIHR HTA Commissioned call 19/124 Effectiveness of meniscal allograft transplantation: METEOR2 National Institute for Health Research (NIHR DoH) 01 Jun 2022 30 Nov 2027
NIHR HTA via M.Costa - Oxford Univ (negotiation phase after Full proposal put forward for funding): Treatment of children with medial epicondyle fractures - SCIENCE - Surgery or Cast for Injuries of the EpicoNdyle in Children's Elbows. A multi-centre prospective randomized superiority trial of operative fixation versus non-operative treatment for medial epicondyle fractures of the humerus. National Institute for Health Research (DoH) 01 Oct 2018 31 Aug 2027
TAR 3 - Production of Technology Assessment Reviews (TAR) National Institute for Health Research (NIHR DoH) 01 Apr 2022 31 Mar 2027
Sugammadex for preventIoN oF pOst-operative pulmoNary complIcAtions (SINFONIA) National Institute for Health Research (NIHR DoH) 01 Jun 2022 01 Nov 2026
NIHR HTA Stage 2: AIRWAYS 3 National Institute for Health Research (NIHR DoH) 01 Jan 2022 31 Dec 2025
NIHR131430: Spinal Immobilisation Study (SIS) lead by Imperial College London National Institute for Health Research (NIHR DoH) 01 May 2022 31 Oct 2025
NIHR HTA Second Stage via Oxford University: CRAFFT ? Children's Radius Acute Fracture Fixation Trial. A multi-centre prospective randomized trial of surgical reduction versus non-surgical casting for displaced distal radius fractures in children. National Institute for Health Research (DoH) 01 Dec 2019 31 Jul 2025
NIHR HTA Stage 2: Pre-hospitAl Randomised triAl of MEDICation route in out-of-hosital cardiac arrest (PARAMEDIC3) National Institute for Health Research (NIHR DoH) 01 May 2021 30 Apr 2025
NIHR HTA Stage 2: Volatile vs Total intravenous Anaesthesia for major non-cardiac surgery ? a randomised controlled triaL (VITAL) National Institute for Health Research (NIHR DoH) 01 Nov 2020 30 Apr 2025
NIHR HTA Led By Oxford_Variation to Collaboration agreement_SCIENCE-Linked to Original award on IDEATE 58214 National Institute for Health Research (NIHR DoH) 01 Nov 2021 31 May 2024
Developing and investigating the acceptability, effectiveness and cost-effectiveness of a complex, sociotechnical hospital ePrescribing-based Antimicrobial Stewardship (ePAMS+) intervention National Institute for Health Research (DoH) 01 Feb 2019 31 Jan 2024
NIHR HS&DR Stage 2: Adapting Breast Cancer Screening to MAximise Mortality Benefit and Minimise Overdiagnosis harm (Adapt-MAMMO) National Institute for Health Research (NIHR DoH) 01 Jan 2021 31 Dec 2023
NIHR HTA Trail: Hypertonic Saline versus Mannitol Hyperosmolar therapy in traumatic brain injury - Lead Trust HEFT National Institute for Health Research (DoH) 01 Jun 2019 30 Nov 2023
NIHR HTA via Oxford: Second Stage: HUSH National Institute for Health Research (DoH) 01 Jan 2020 31 Oct 2023
NIHR HTA Costed Extension: ARTISAN 12 Months costed extension National Institute for Health Research (NIHR DoH) 01 Dec 2021 30 Nov 2022
NIHR HTA:COVID-19 recovery and learning_Rehabilitation Exercise and psycholoGical support After covid-19 InfectioN (REGAIN) National Institute for Health Research (NIHR DoH) 01 Sep 2020 31 Aug 2022
NIHR HTA Second Stage: Exercise training in pulmonary hypertension National Institute for Health Research (DoH) 01 Jun 2019 31 Aug 2022
NIHR HTA Lead by University of Oxford-FAME Linked to IDEATE 59893-Novation agreement to refelct transfer of Prof R. Kearny to University of Bristiol National Institute for Health Research (NIHR DoH) 01 May 2019 30 Jun 2022
UK study of ankle fracture rehabilitation ? multicentre randomised controlled trial. NIHR CDF Fellowship. National Institute for Health Research (DoH) 01 Jan 2017 30 Jun 2022
A Randomised, Efficient, Adaptive Clinical Trial in Surgery: Assessment of a Biodegradeable Spacer for Tears of the RotAtor Cuff Tendons (STARTS:REACTS) National Institute for Health Research (DoH) 01 Jan 2018 31 Jan 2022
ARTISAN National Institute for Health Research (DoH) 01 Jun 2018 30 Nov 2021
NIHR HTA via Dan Perry - Oxford Univ (negotiation phase after Full proposal put forward for funding): FORCE National Institute for Health Research (DoH) 01 Jul 2018 31 Dec 2020
NIHR RfPB Second Stage: Multicentre feasibility study for a randomised controlled trial of intra operative cell salvage versus conventional care in patients undergoing surgery for hip fracture National Institute for Health Research (DoH) 01 Apr 2019 30 Sep 2020
CAPACITY National Institute for Health Research (DoH) 01 Oct 2015 30 Jun 2020
DIAMOND Lewy National Institute for Health Research (DoH) 01 Oct 2015 30 Sep 2018
MAVRIC National Institute for Health Research (DoH) 01 Oct 2015 31 May 2018
Health Interventions in Volcanic Eruption crises (HIVE) (Durham PI) Save the Children Fund 01 Nov 2015 31 Oct 2017