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Dr Jane Warwick

Job Title
Professor
Department
WMS - Warwick Clinical Trials Unit
Email
J.Warwick@warwick.ac.uk_FORMER
Web Link
Link
Research Interests

Jane's current research is largely focused on trials in mental health, surgery, emergency medicine and critical care, and on the use of frailty indices as a measure of general health, biological ageing and prognosis in the very elderly. Previously, her research focused on the evaluation of breast screening programmes, breast cancer aetiology, breast cancer prevention, models to predict breast cancer risk and clinical trials in gynaecological oncology and she maintains an interest in these areas.

Biography

Jane Warwick is Professor in Clinical Trials Statistics, Warwick Clinical Trials Unit (WCTU), Warwick Medical School, University of Warwick, where she works to further develop Warwick CTU's portfolio of pragmatic clinical trials and related statistical research studies. She has over 25 years' experience in medical statistics, epidemiology and clinical trials. She obtained a BSc in Statistics (2.1) from the University of Birmingham (1987) and a PhD (thesis entitled "Selecting tuning parameters in minimum distance estimators", funded by an Open University Studentship, supervisor Professor M.C. Jones) from the Department of Mathematics and Statistics at the Open University (2002). Her first post in medical statistics was at the Cancer Research Campaign Clinical Trials Unit at the University of Birmingham where she specialised in gynaecological oncology and developed a particular interest in ovarian cancer. After completing her PhD she joined the Cancer Research UK Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London where for ten years she worked with Professor Stephen Duffy on the evaluation of breast screening programmes and breast cancer aetiology and with Professor Jack Cuzick on breast cancer prevention and models to predict breast cancer risk. In 2011, in order to broaden her experience and develop her leadership skills, she moved to Imperial Clinical Trials Unit, Imperial College London, where for 3 years she led the statistics team and gained experience of Phase II and III trials in a variety of clinical areas, including cancer, HIV, mental health, vascular surgery and critical care, and of Bayesian methods for adaptive trial designs. She joined Warwick CTU in 2014. She maintains her interest in cancer research through membership of external oversight committees (as independent statistician) and has for many years been a reviewer for the NIHR EME and HTA programmes, and for Cancer Research UK's Science Committee. In 2014 she was awarded the Translational Cancer Research Prize for her contribution to the IBIS team (led by Prof Jack Cuzick QMUL), specifically the design and analysis of the mammographic density sub-studies and the development of the methodology for incorporating mammographic density into the IBIS breast cancer risk evaluation model.

Title Funder Award start Award end
NIHR RIGHT programme - Stage 2: TRANSFORM project (related to 61743 outline): An asseT-based appRoAch FOR improving access to Mental health care in slums: the TRAnsFORM Project National Institute for Health Research (DoH) 01 Sept 2020 31 Aug 2025
RECEDE study (Reducing Colonoscopies in those without bowEl DiseasE) HS&DR Stage 2 (Stage 1 - 60439) National Institute for Health Research (DoH) 01 May 2020 31 Oct 2022
UK study of ankle fracture rehabilitation ? multicentre randomised controlled trial. NIHR CDF Fellowship. National Institute for Health Research (DoH) 01 Jan 2017 30 Jun 2022
Parenting Intervention to Prevent Effective Disorders (PIPA) (2nd Stage Application) National Institute for Health Research (DoH) 01 Sept 2018 31 May 2022
NIHR PDF 2015 - Peter Wall: SAFE-TKR study (Safety and feasibility evaluation of tourniquets for knee replacement study) National Institute for Health Research (DoH) 01 Jan 2016 31 Dec 2020
ADDEVRA 5 Year Follow up of Early Venous Reflux Ablation Study EVRA National Institute for Health Research (DoH) 01 May 2018 30 Jun 2019
ViPP- Healthy Start, Happy Start - Project with Imperial College London National Institute for Health Research (DoH) 01 Oct 2014 31 Mar 2019
Research Methods Fellowship National Institute for Health Research (DoH) 01 Oct 2016 30 Sept 2018
Use of Methylnaltrexone for the Treatment of Opioid Induced Constipation & Gastro-Intestinal Stasis in Intensive Care Patients (MOTION) National Institute for Health Research (DoH) 01 Nov 2014 31 Oct 2016

All authors for Protocol for the development and validation procedure of the managing the link and strengthening transition from child to adult mental health care (MILESTONE) suite of measures

Santosh, P., Adams, L., Fiori, F., Davidovic, N., de Girolamo, G., Dieleman, G. C., Franic, T., Heaney, N., Lievesley, K., Madan, Jason, Maras, A., Mastroianni, M., McNicholas, F., Paul, Moli, Purper-Ouakil, D., Sagar-Ouriaghli, I., Schulze, U., Signorini, G., Street, Catherine, Tah, Priya, Tremmery, S., Tuomainen, Helena, Verhulst, F. C., Warwick, Jane, Wolke, Dieter, Singh, J., Singh, Swaran P.

All authors for Validation of the Transition Readiness and Appropriateness Measure (TRAM) for the Managing the Link and Strengthening Transition from Child to Adult Mental Healthcare in Europe (MILESTONE) study

Santosh, Paramala, Singh, Jatinder, Adams, Laura, Mastroianni, Mathilde, Heaney, Natalie, Lievesley, Kate, Sagar-Ouriaghli, Ilyas, Allibrio, Giovanni, Appleton, Rebecca, Davidovic, Nikolina, de Girolamo, Giovanni, Dieleman, Gwen, Dodig-Curkovic, Katarina, Franic, Tomislav, Gatherer, Charlotte, Gerritsen, Suzanne, Gheza, Elisa, Madan, Jason, Manenti, Lidia, Maras, Athanasios, Margari, Francesco, McNicholas, Fiona, Pastore, Adriana, Paul, Moli, Purper-Ouakil, Diane, Rinaldi, Francesco, Sakar, Vehbi, Schulze, Ulrike, Signorini, Giulia, Street, Cathy, Tah, Priya, Tremmery, Sabine, Tuffrey, Amanda, Tuomainen, Helena, Verhulst, Frank, Warwick, Jane, Wilson, Anna, Wolke, Dieter, Fiori, Federico, Singh, Swaran

All authors for Investigation of antihypertensive class, dementia, and cognitive decline

Peters, Ruth, Yasar, Sevil, Anderson, Craig S., Andrews, Shea, Antikainen, Riitta, Arima, Hisatomi, Beckett, Nigel, Beer, Joanne C., Bertens, Anne Suzanne, Booth, Andrew, van Boxtel, Martin, Brayne, Carol, Brodaty, Henry, Carlson, Michelle C., Chalmers, John, Corrada, Maria, DeKosky, Steven, Derby, Carol, Dixon, Roger A., Forette, Françoise, Ganguli, Mary, van Gool, Willem A., Guaita, Antonio, Hever, Ann M., Hogan, David B., Jagger, Carol, Katz, Mindy, Kawas, Claudia, Kehoe, Patrick G., Keinanen-Kiukaanniemi, Sirkka, Kenny, Rose Ann, Köhler, Sebastian, Kunutsor, Setor K., Laukkanen, Jari, Maxwell, Colleen, McFall, G. Peggy, van Middelaar, Tessa, Moll van Charante, Eric P., Ng, Tze-Pin, Peters, Jean, Rawtaer, Iris, Richard, Edo, Rockwood, Kenneth, Rydén, Lina, Sachdev, Perminder S., Skoog, Ingmar, Skoog, Johan, Staessen, Jan A., Stephan, Blossom C. M., Sebert, Sylvain, Thijs, Lutgarde, Trompet, Stella, Tully, Phillip J., Tzourio, Christophe, Vaccaro, Roberta, Vaaramo, Eeva, Walsh, Erin, Warwick, Jane, Anstey, Kaarin J.

All authors for Cost-effectiveness analysis of a randomized clinical trial of early versus deferred endovenous ablation of superficial venous reflux in patients with venous ulceration

Epstein, D. M., Gohel, M. S., Heatley, F., Liu, X., Bradbury, A., Bulbulia, R., Cullum, N., Nyamekye, I., Poskitt, K. R., Renton, S., Warwick, Jane, Davies, A. H., Gohel, M. S., Read, D., Hargreaves, S., Dhillon, K., Anwar, M., Liddle, A., Brown, H., Mercer, K., Gill, F., Liu, A., Jepson, W., Wormwell, A., Rafferty, H., Davies, A. H., Dhillon, K., Kaur, R., Solomon, E., Sritharan, K., Velineni, R., Lim, C. S., Busuttil, A., Bootun, R., Bicknell, C., Jenkins, M., Lane, T., Serjeant, E., Poskitt, K., Bulbulia, R., Waldron, J., Wolfrey, G., Slim, F., Davies, C., Emerson, L., Grasty, M., Whyman, M., Wakeley, C., Cooper, A., Clapp, J., Hogg, N., Howard, J., Dyer, J., Lyes, S., Teemul, D., Harvey, K., Pride, M., Kindon, A., Price, H., Flemming, L., Birch, G., Holmes, H., Weston, J., Joseph, T., Eiffel, R., Ojimba, T., Wilson, T., Hodgson, A., Robinson, L., Todhunter, J., Heagarty, D., Mckeane, A., McCarthy, R., Barwell, J., Northcott, C., Elstone, A., West, C., Chong, P., Gerrard, D., Croucher, A., Levy, S., Martin, C., Craig, T., Carradice, D., Firth, A., Clarke, E., Oswald, A., Sinclair, J., Chetter, I., El-Sheikha, J., Nandhra, S., Leung, C., Scott, J., Dewhirst, N., Woods, J., Russell, D., Darwood, R., Troxler, M., Thackeray, J., Bell, D., Watson, D., Williamson, L., Coulston, J., Eyers, P., Darvall, K., Hunter, I., Stewart, A., Moss, A., Rewbury, J., Adams, C., Vickery, L., Foote, L., Durman, H., Venn, F., Hill, P., James, K., Luxton, F., Greenwell, D., Roberts, K., Mitchell, S., Tate, M., Mills, H., Garnham, A., Hobbs, S., McIntosh, D., Green, M., Collins, K., Rankin, J., Poulton, P., Isgar, V., Renton, S., Dhillon, K., Trivedi, M., Kafeza, M., Parsapour, S., Moore, H., Najem, M., Connarty, S., Albon, H., Lloyd, C., Trant, J., Vohra, R., McCormack, J., Marshall, J., Hardy, V., Rogoveanu, R., Goff, W., Garnham, A., Gidda, R., Merotra, S., Shiralkar, S., Jayatunga, A., Pathak, R., Rehman, A., Randhawa, K., Lewis, J., Fullwood, S., Jennings, S., Cole, S., Wall, M., Ranaboldo, C., Hulin, S., Clarke, C., Fennelly, R., Cooper, R., Boyes, R., Draper, C., Harris, L., Mead, D., Bradbury, A., Kelly, L., Bate, G., Davies, H., Popplewell, M., Claridge, M., Gannon, M., Khaira, H., Scriven, M., Wilmink, T., Adam, D., Nasr, H., Dodd, D., Nawaz, S., Humphreys, J., Barnes, M., Sorrell, J., Swift, D., Phillips, P., Trender, H., Fenwick, N., Rittoo, D., Baker, S., Mitchell, R., Andrews, S., Williams, S., Stephenson, J., Nyamekye, I., Holloway, S., Hayes, W., Day, J., Clayton, C., Harding, D., Thompson, A., Gibson, A., Murphy, Z., Smith, T.

All authors for The interface between child/adolescent and adult mental health services : results from a European 28-country survey

Signorini, Giulia, Singh, Swaran P., Marsanic, Vlatka Boricevic, Dieleman, Gwen, Dodig-Curkovic, Katarina, Franic, Tomislav, Gerritsen, Suzanne E., Griffin, James M., Maras, Athanasios, McNicholas, Fiona, O'Hara, Lesley, Purper-Ouakil, Diane, Paul, Moli, Russet, Frederick, Santosh, Paramala, Schulze, Ulrike, Street, Catherine, Tremmery, Sabine, Tuomainen, Helena, Verhulst, Frank, Warwick, Jane, de Girolamo, Giovanni

All authors for Protocol for a cohort study of adolescent mental health service users with a nested cluster randomised controlled trial to assess the clinical and cost-effectiveness of managed transition in improving transitions from child to adult mental health services (the MILESTONE study)

Singh, Swaran P., Tuomainen, Helena, de Girolamo, Giovanni, Maras, Athanasios, Santosh, Paramala, McNicholas, Fiona, Schulze, Ulrike, Purper-Ouakil, Diane, Tremmery, Sabine, Franic, Tomislav, Madan, Jason, Paul, Moli, Verhulst, F. C., Dieleman, Gwen, Warwick, Jane, Wolke, Dieter, Street, Catherine, Daffern, Claire, Tah, Priya, Griffin, James M., Canaway, Alastair, Signorini, Giulia, Gerritsen, Suzanne E., Adams, Laura, O?Hara, Lesley, Aslan, Sonya, Russet, Frédérick, Davidovi?, Nikolina, Tuffrey, Amanda, Wilson, Anna, Gatherer, Charlotte

All authors for A two decade dementia incidence comparison from the cognitive function and ageing studies I and II

Matthews, F. E., Stephan, B. C. M., Robinson, L., Jagger, C., Barnes, L. E., Arthur, A., Brayne, C., Comas-Herrera, A., Wittenberg, R., Dening, T., McCracke, C. F. M., Moody, C., Parry, B., Green, E., Barnes, R., Warwick, Jane, Gao, L., Mattison, A., Baldwin, C., Harrison, S., Woods, B., McKeit, I. G., Ince, P. G., Wharton, S. B., Forster, G.

All authors for Therapeutic targeting of integrin avß6 in breast cancer

Moore, Kate M., Thomas, Gareth J., Duffy, Stephen W., Warwick, Jane, Gabe, Rhian, Chou, Patrick, Ellis, Ian, Green, Andrew R., Haider, Syed, Brouilette, Kellie, Saha, Antonio, Vallath, Sabari, Bowen, Rebecca, Chelala, Claude, Eccles, Diana, Tapper, Will, Thompson, Alastair M., Quinlan, Phillip, Jordan, Lee, Gillett, Cheryl, Brentnall, Adam, Violette, Sheila, Weinreb, Paul H., Kendrew, Jane, Barry, Simon T., Hart, I. R. (Ian R.), Jones, J. Louise, Marshall, John F.

All authors for Effect of mammographic service screening on stage at presentation of breast cancers in Sweden

Duffy, S. W., Tabár, L., Chen, T. H. H., Smith, R. A., Holmberg, L., Jonsson, H., Lenner, P., Nyström, L., Törnberg, S., Frisell, J., Yen, A. M. F., Chen, L. S., Chiu, Y. H., Wu, C. Y., Wu, H. M., Huang, C. C., Warwick, Jane, Kemetli, L., Chou, P., Svane, G., Azavedo, E., Grundström, H., Sundén, P., Leifland, K., Moberg, K., Sahlstedt, T., Bordás, P., Starck, L., Carlson, S., Laaksonen, H., Abdsaleh, S., Thurfjell, E., Epstein, B., Tholin, M., Frodis, E., Sundbom, A., Wiege, M., Åkerlund, A., Lundgren, B.