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Professor Ranjit Lall

Job Title
Professor of Clinical Trials
Department
WMS - Warwick Clinical Trials Unit
Phone
024 7657 4649
Research Interests

Design and analysis of complex intervention clinical trials in critical care and rehabilitation.

Biography

I qualified with a BSc in Mathematics and MSc in Medical Statistics at the University of Leicester. In 2004, I obtained my PhD in "The application of Ordinal Regression Models in Quality of Life Scales used in Gerontology" at the University of Sheffield, in the Faculty of Medicine.

As a Professor of Clinical Trials and Biostatistics at the Warwick Clinical Trials Unit (WCTU), I provide oversight to the Statistics Group at the Warwick Clinical Trials Unit and lead on the design and analysis of an internationally competitive and sustainable portfolio of clinical trials in the area of complex interventions (rehabilitation and accident and emergency care). I have responsibility, with the Director, for the strategic management and development of the WCTU, gaining world-wide recognition for excellence in the conduct of randomized controlled trials. My contributions towards this aim have included taking the lead in delivering the Conference of Clinical Trials of Complex Interventions and Multi-components (April 2015, Warwick) and taking the lead on delivering the Workshop in the Design and Analysis of Complex Interventions (at the International Clinical Trials Methodology Conference, Glasgow, 2015).

As a member of the Senior Management Team, one of my responsibilities is the continued development of the statisticians in the WCTU. I have successfully secured funding for a NIHR HTA Methodology Fellowship awards and I current manage a team of research fellows and associate research fellows statisticians. In collaboration with the Mathematics Department at Warwick University, I am proactive and committed in providing development opportunities and training for MSc students who seek summer work placements, in the view that they develop a career path in the area of statistics in clinical trials. Currently I am a main supervisor on four PhD students.

Title Funder Award start Award end
Awake prone positioning in patients with acute hypoxaemic respiratory failure not due to COVID-19: a multi-centre, pragmatic, allocation concealed, individual patient randomised, parallel group, open-label clinical trial (AWAKE-PRONE) National Institute for Health Research (NIHR DoH) 01 Jan 2024 31 Dec 2027
NIHR HTA Stage 2:RESTORE Lead by UHCW. Award Reference NIHR157510 National Institute for Health Research (NIHR DoH) 01 Jul 2024 31 Mar 2027
NIHR HTA Stage 2: AIRWAYS 3 National Institute for Health Research (NIHR DoH) 01 Jan 2022 31 Dec 2025
NIHR131430: Spinal Immobilisation Study (SIS) lead by Imperial College London National Institute for Health Research (NIHR DoH) 01 May 2022 31 Oct 2025
NIHR HTA Stage 2: Pre-hospitAl Randomised triAl of MEDICation route in out-of-hosital cardiac arrest (PARAMEDIC3) National Institute for Health Research (NIHR DoH) 01 May 2021 30 Apr 2025
ADAPT (71551)- 6 month costing extension National Institute for Health Research (NIHR DoH) 01 Aug 2024 31 Jan 2025
NIHR: Rehab after ICU_Lead by Ulster University National Institute for Health Research (NIHR DoH) 01 Jan 2022 31 Dec 2024
Linked to 50255 ADAPT Sepsis Biomarker-guided duration of antibiotic treatment in hospitalised patients with moderate or severe sepsis. NIHR HTA via Salford Royal Infirmary: 15/99 request for costed extension National Institute for Health Research (NIHR DoH) 22 Jul 2022 31 Jul 2024
NIHR HTA 2nd stage. A randomised controlled trial of PAramediC analgesia Comapring Ketamine and MorphiNe in trauma (PACKMaN) National Institute for Health Research (DoH) 01 Sept 2019 31 May 2024
To improve methods for developing and reporting composite primary endpoints in surgical trials, focussing on chronic limb threatening ischaemia as an exemplar case study Academy of Medical Sciences 01 Apr 2022 31 Mar 2024
AWARD: RECOVERY-RS Respiratory Support: Respiratory Strategies in COVID-19; CPAP, High-flow, and standard care (link to 65887 - temp Site agreement) National Institute for Health Research (NIHR DoH) 01 Apr 2020 29 Feb 2024
Costed Extension:REGAIN Rehabilitation Exercise and psycholoGical support After covid-19 InfectioN National Institute for Health Research (NIHR DoH) 01 Sept 2022 31 Dec 2023
Big Baby Extension links to record 53633 National Institute for Health Research (NIHR DoH) 01 Jul 2021 31 Dec 2023
NIHR HTA Trail: Hypertonic Saline versus Mannitol Hyperosmolar therapy in traumatic brain injury - Lead Trust HEFT National Institute for Health Research (DoH) 01 Jun 2019 30 Nov 2023
Randomised controlled trial of doxycycline versus placebo in women presenting with chronic endometritis for the prevention of miscarriage National Institute for Health Research (DoH) 01 Jun 2019 31 May 2023
NIHR CDRF Second Stage: A feasibility study for a Randomised Trial to assess Prehospital Optimal Shock Energy for Defibrillation in cardiac arrest (POSED) National Institute for Health Research (DoH) 01 May 2019 30 Apr 2023
NIHR EME Via University of Newcastle National Institute for Health Research (NIHR DoH) 01 Aug 2020 31 Mar 2023
Meta-analysis of three large NIHR HTA UK based Clinical Trials in Out-of-hospital Cardiac Arrest Resuscitation Council (UK) 01 Apr 2021 31 Oct 2022
NIHR HTA:COVID-19 recovery and learning_Rehabilitation Exercise and psycholoGical support After covid-19 InfectioN (REGAIN) National Institute for Health Research (NIHR DoH) 01 Sept 2020 31 Aug 2022
NIHR HS&DR Full stage. Termination of resuscitation in UK ambulance services PROTECTED National Institute for Health Research (DoH) 01 Sept 2019 31 Aug 2022
NIHR HTA Second Stage: Exercise training in pulmonary hypertension National Institute for Health Research (DoH) 01 Jun 2019 31 Aug 2022
Biomarker-guided duration of antibiotic treatment in hospitalised patients with moderate or severe sepsis. NIHR HTA via Salford Royal Infirmary: 15/99 National Institute for Health Research (DoH) 01 Apr 2017 31 Jul 2022
NIHR HS&DR Full Stage: Optimisation of the Deployment of Automated External Defibrillators in Public Places in England National Institute for Health Research (DoH) 01 Oct 2019 30 Jun 2022
COVID-19 and out-of-hospital cardiac arrest: an epidemiological study Resuscitation Council (UK) 01 Oct 2021 31 Jan 2022
NIHR EME via UHB: STudy into the REversal of Septic Shock with Beta Blockade (STRESS-BB) National Institute for Health Research (DoH) 01 Jun 2017 30 Jul 2021
NIHR HTA Induction of labour at 39 weeks for predicted macrosomia National Institute for Health Research (DoH) 01 Jan 2018 30 Jun 2021
The application of Spatial Analysis methods to clinical trial data and registry data Research Methods Fellowship National Institute for Health Research (DoH) 01 Oct 2018 31 Mar 2021
Improving the wellbeing of people with Opioid treated chronic pain: I-WOTCH National Institute for Health Research (DoH) 01 Sept 2016 30 Nov 2020
NIHR PDF 2015 - Keith Couper - A feasibility study of the use of the mechanical CPR for in-hospital cardiac arrest. National Institute for Health Research (DoH) 01 Oct 2015 30 Sept 2019
Exercise to prevent shoulder conditions in patients undergoing breast cancer treatment. The PRevention Of Shoulder Problems Study (PROSPER) National Institute for Health Research (DoH) 01 Mar 2015 28 Feb 2019
NIHR Research Methods Fellowship 2015 National Institute for Health Research (DoH) 01 Mar 2016 28 Feb 2018
Exercise in Dementia, DAPA The Human Tissue Authority (HTA) 01 Apr 2011 31 Mar 2017
NIHR HTA FULL: Scoliosis feasibility trial National Institute for Health Research (DoH) 01 Sept 2011 31 Aug 2013
HFOV - High Frequency Ventilation for Acute Lung Injury and Acute Respiratory OSCAR Distress Syndrome National Institute for Health Research (DoH) 01 Jun 2007 31 May 2012
What Happens to People with Dementia After Discharge from General Hospital? Alzheimers Society 01 Jan 2008 30 Sept 2010
A Phase I Study of the Self-efficacy Goal Achievement (SEGA) Brief Psychological Intervention for Type 2 Diabetes MRC 01 Mar 2005 28 Feb 2006