Job Title
Principal Research Fellow
Department
WMS - Warwick Clinical Trials Unit
Phone
02476 150 177
- Lin, Daniel J., McConkey, Christopher C., Nankivell, Paul, Dunn, Janet A., Mehanna, Hisham, 2018. The impact of institutional clinical trial recruitment versus hospital volume on survival outcomes of patients with head and neck cancer : an analysis of the PET-NECK trial outcomes, UKCRN portfolio, and Hospital Episode Statistics (HES) in England. Oral Oncology, 85, pp. 40-43
- Smith, A. F., Hall, P. S., Hulme, C. T., Dunn, Janet A., McConkey, Christopher C., Rahman, J. K., McCabe, C., Mehanna, H., 2017. Cost-effectiveness analysis of PET-CT-guided management for locally advanced head and neck cancer. European Journal of Cancer, 85, pp. 6-14
- Williamson, Esther, McConkey, Christopher C., Heine, Peter, Dosanjh, Sukhdeep, Williams, Mark, Lamb, S. E. (Sallie E.), 2017. Hand exercises for patients with rheumatoid arthritis : an extended follow-up of the SARAH randomised controlled trial.. BMJ Open, 7 (4)
- Mehanna, H., McConkey, Christopher C., Rahman, J., Wong, W. L., Smith, A. F., Nutting, C., Hartley, A. G. J., Hall, P., Hulme, C., Patel, D., Von Zeidler, S. V., Robinson, M., Sanghera, B., Fresco, L., Dunn, Janet A., 2017. PET-NECK : a multicentre randomised Phase III non-inferiority trial comparing a positron emission tomography-computerised tomography-guided watch-and-wait policy with planned neck dissection in the management of locally advanced (N2/N3) nodal metastases in patients with squamous cell head and neck cancer. Health Technology Assessment, 21 (17), pp. 1-122
- Hartley, A., Fong, C., Sanghera, P., Wong, W. L., McConkey, Christopher C., Rahman, J., Nutting, C. M., Al-Booz, H., Robinson, M., Junor, E., Rizwaah, M., Dunn, Janet A., Mehanna, H., 2016. Radiation therapy variation in the Randomized Phase 3 Positron Emission Tomography Neck Study. International Journal of Radiation Oncology Biology Physics, 96 (2)
- Williams, Mark A., Williamson, Esther M., Heine, Peter J., Nichols, Vivien P., Glover, Matthew J., Dritsaki, Melina, Adams, Jo, Dosanjh, Sukhdeep, Underwood, Martin, Rahman, Anisur, McConkey, Christopher C., Lord, Joanne, Lamb, Sallie, 2015. Strengthening and stretching for rheumatoid arthritis of the hand (SARAH). A randomised controlled trial and economic evaluation. Health Technology Assessment, 19 (19), pp. 1-222
- Bartlett, J. M. S., McConkey, Christopher C., Munro, A. F., Desmedt, C., Dunn, Janet A., Larsimont, D., O'Malley, F. P., Cameron, D. A., Earl, H., Poole, Christopher J., Shepherd, L. E., Cardoso, F., Jensen, M., Caldas, C., Twelves, C. J., Rea, D. W., Ejlertsen, B., Di Leo, A., Pritchard, K. I., 2015. Predicting anthracycline benefit : TOP2A and CEP17-not only but also. European Journal of Cancer Care, 33 (15), pp. 1680-1687
- Lamb, S. E. (Sallie E.), Williamson, Esther M., Heine, Peter J., Adams, Jo, Dosanjh, Sukhdeep, Dritsaki, Melina, Glover, Matthew, Lord, Joanne, McConkey, Christopher C., Nichols, Vivien P., Rahman, Anisur, Underwood, Martin, Williams, Mark A., 2015. Exercises to improve function of the rheumatoid hand (SARAH) : a randomised controlled trial. The Lancet, 385 (9966), pp. 421-429
- Huijbers, A., Tollenaar, R. A. E. M., v Pelt, G. W., Zeestraten, E. C. M., Dutton, S., McConkey, Christopher C., Domingo, E., Smit, V. T. H. B. M., Midgley, R., Warren, B. F., Johnstone, E. C., Kerr, D. J., Mesker, W. E., 2013. The proportion of tumor-stroma as a strong prognosticator for stage II and III colon cancer patients : validation in the VICTOR trial. Annals of Oncology, 24 (1), pp. 179-185
- Nankivell, Paul, Williams, Hazel, Matthews, Paul, Suortamo, Sari, Snead, David R. J., McConkey, Christopher C., Mehanna, Hisham M., 2013. The binary oral dysplasia grading system : validity testing and suggested improvement. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 115 (1), pp. 87-94
- Nankivell, Paul C., Williams, H., McConkey, Christopher C., Webster, Keith, High, A., MacLennan, Ken, Senguven, B., Rabbitts, P., Mehanna, Hisham M., 2013. Tetraspanins CD9 and CD151, epidermal growth factor receptor and cyclooxygenase-2 expression predict malignant progression in oral epithelial dysplasia. British Journal of Cancer, 109 (11), pp. 2864-2874
- Meade, Sara, Sanghera, Paul, McConkey, Christopher C., Fowler, Jack, Fountzilas, George, Glaholm, John, Hartley, Andrew, 2013. Revising the radiobiological model of synchronous chemotherapy in head-and-neck cancer : a new analysis examining reduced weighting of accelerated repopulation. International Journal of Radiation Oncology*Biology*Physics, 86 (1), pp. 157-163
- Meade, Sara, McConkey, Christopher C., Sanghera, Paul, Mehanna, Hisham M., Hartley, Andrew, 2013. Revised radiobiological modelling of the contribution of synchronous chemotherapy to the rate of grades 3-4 mucositis in head and neck cancer. Journal of Medical Imaging and Radiation Oncology, 57 (6), pp. 733-738
- McCaul, James A., Cymerman, James A., Hislop, Stuart, McConkey, Christopher C., McMahon, Jeremy, Mehanna, Hisham M., Shaw, Richard, Sutton, David N., Dunn, Janet A., 2013. LIHNCS - Lugol's iodine in head and neck cancer surgery : a multicentre, randomised controlled trial assessing the effectiveness of Lugol's iodine to assist excision of moderate dysplasia, severe dysplasia and carcinoma in situ at mucosal resection margins of oral and oropharyngeal squamous cell carcinoma : study protocol for a randomised controlled trial. Trials, 14 (1)
- Adams, Jo, Bridle, Christopher, Dosanjh, Sukhdeep, Heine, Peter J., Lamb, S. E. (Sallie E.), Lord, J., McConkey, Christopher C., Nichols, Vivien P., Toye, Francine, Underwood, Martin, Williams, Mark A., Williamson, Esther M., 2012. Strengthening and stretching for rheumatoid arthritis of the hand (SARAH) : design of a randomised controlled trial of a hand and upper limb exercise intervention - ISRCTN89936343. BMC Musculoskeletal Disorders, Vol.13 (No.1)
- Mehanna, Hisham M., Beech, Tom, Nicholson, Tom, El-Hariry, Iman, McConkey, Christopher C., Paleri, Vinidh, Roberts, Sally, Eisele, David W., 2012. Prevalence of human papillomavirus in oropharyngeal and nonoropharyngeal head and neck cancer-systematic review and meta-analysis of trends by time and region. Head & Neck, 35 (5), pp. 747-755
- Chan, Anthony K. C., Sanghera, Paul, Choo, B. A., McConkey, Christopher C., Mehanna, Hisham M., Parmar, Satyesh, Pracy, P., Glaholm, John, Hartley, Andrew, 2011. Hypofractionated accelerated radiotherapy with concurrent carboplatin for locally advanced squamous cell carcinoma of the head and neck. Clinical Oncology, 23 (1), pp. 34-39
- Nankivell, Paul, Weller, Matthew, McConkey, Christopher C., Paleri, Vinidh, Mehanna, Hisham M., 2011. Biomarkers in laryngeal dysplasia : a systematic review. Head & Neck, Vol.33 (No.8), pp. 1170-1176
- Hartley, Andrew, Sanghera, Paul, Kazi, W., Mehanna, Hisham M., McConkey, Christopher C., Glaholm, John, Fowler, J. (Jack), 2011. Correlation of currently used radiobiological parameters with local control and acute and late mucosal toxicity in randomised studies of altered fractionation for locally advanced head and neck cancer. Clinical Oncology, 23 (1), pp. 29-33
- Midgley, Rachel S., McConkey, Christopher C., Johnstone, Elaine C., Dunn, Janet A., Smith, Justine L., Grumett, Simon A., Julier, Patrick, Iveson, Claire, Yanagisawa, Yoko, Warren, Bryan, Langman, Michael J., Kerr, David J., 2010. Phase III randomized trial assessing rofecoxib in the adjuvant setting of colorectal cancer: final results of the VICTOR trial. Journal of Clinical Oncology, Vol.28 (No.30), pp. 4575-4580
- Hartley, A., Sanghera, P., Glaholm, J., Mehanna, Hisham M., McConkey, C., Fowler, J., 2010. Radiobiological modelling of the therapeutic ratio for the addition of synchronous chemotherapy to radiotherapy in locally advanced squamous cell carcinoma of the head and neck. Clinical Oncology, Vol.22 (No.2), pp. 125-130
- Bartlett, John M. S., Munro, Alison F., Dunn, Janet A., McConkey, Christopher C., Jordan, S., Twelves, Chris, Cameron, D., Thomas, Jeremy St. J., Campbell, Fiona M., Rea, Daniel W., Provenzano, Elena, Caldas, Carlos, Pharaoh, Paul, Hiller, Louise, Earl, Helena M., Poole, Christopher, 2010. Predictive markers of anthracycline benefit : a prospectively planned analysis of the UK national epirubicin adjuvant trial (NEAT/BR9601). Lancet Oncology, Vol.11 (No.3), pp. 266-274
- Mehanna, Hisham M., Rattay, Tim, Smith, Joel, McConkey, Christopher C., 2009. Treatment and follow-up of oral dysplasia - a systematic review and meta-analysis. Head & Neck, Vol.31 (No.12), pp. 1600-1609
- Sanghera, P., Wong, D. W. Y., McConkey, Christopher C., Geh, J. I., Hartley, A., 2008. Chemoradiotherapy for rectal cancer : an updated analysis of factors affecting pathological response. Clinical Oncology, Vol.20 (No.2), pp. 176-183
- Sanghera, P., Arnfield, John, McConkey, Christopher C., Hartley, A., 2008. Gap compensation during accelerated hypofractionated radiotherapy in head and neck cancer. Journal of Radiotherapy in Practice, Vol.7 (No.1), pp. 31-38
- Kerr, David J., Dunn, Janet A., Langman, Michael J., Smith, Justine L., Midgley, Rachel S. J., Stanley, Andrew, Stokes, Joanne C., Julier, Patrick, Iveson, Claire, Duvvuri, Ravi, McConkey, Christopher C., 2007. Rofecoxib and cardiovascular adverse events in adjuvant treatment of colorectal cancer. New England Journal Of Medicine, Vol.357 (No.4), pp. 360-369
- Sanghera, Paul, McConkey, Christopher C., Ho, Kean-Fatt, Glaholm, John, Hartley, Andrew, 2007. Hypofractionated accelerated radiotherapy with concurrent chemotherapy for locally advanced squamous cell carcinoma of the head and neck. International Journal of Radiation: Oncology - Biology - Physics, Vol.67 (No.5), pp. 1342-1351
- Gray, Richard, Barnwell, Jennifer, McConkey, Christopher C., Hills, Robert K., Williams, Norman S., Kerr, David J., 2007. Adjuvant chemotherapy versus observation in patients with colorectal cancer : a randomised study. Lancet, Vol.370 (No.9604), pp. 2020-2029
- Hartley, A. G., Sanghera, P., McConkey, Christopher C., Mehanna, Hisham M., Glaholm, J., Fowler, J., 2009. Modeling the contribution of synchronous chemotherapy to the rate of grade 3 and 4 mucositis in locally advanced squamous cell carcinoma of the head and neck. 51st Annual Meeting of the American Society for Radiation Oncology, Chicago, IL, November 01-05, 2009, Published in International Journal of Radiation: Oncology - Biology - Physics, pp. S394-S394
- Dunn, Janet A., Balmer, Claire E., McConkey, Christopher C., Nutting, Chris, Fisher, Sheila, Wong, Wai Lup, MacLennan, Ken, McCabe, Chris, Hulme, Claire, Mehanna, Hisham M., 2008. PET-NECK : setting up a collaborative clinical trial in a rare disease site. Society for Clinical Trials Annual Meeting 2008
- Midgley, Rachel S. J., McConkey, Christopher C., Langman, Michael J., Smith, Justine L., Julier, Patrick, Iveson, Claire, Johnstone, Elaine, Chen, Xiao-he, Dunn, Janet A., Kerr, David J., 2008. VICTOR : a phase III placebo-controlled trial of rofecoxib in colorectal cancer patients following surgical resection. 33rd European Society for Medical Oncology Congress, Stockholm, Sweden, 12-16 Sept 2008, Published in Annals of Oncology, pp. 1-1
- Sanghera, P., Arnfield, J., McConkey, C., Hartley, A., 2007. Gap compensation for accelerated hypofractionated schedules. UK Radiation Oncology Conference, Edinburgh, March 19-27, 2007, Published in Clinical Oncology, pp. S45-S45
- Sanghera, P., McConkey, C., Ho, K. F., Glaholm, J., Hartley, A., 2007. Synchronous chemotherapy and hypofractionated accelerated radiotherapy for locally advanced squamous cell carcinomas of the head and neck. International Meeting on Innovative Approaches in Head and Neck Oncology, Barcelona, Spain, February 22-27, 2007, Published in Radiotherapy and Oncology, pp. S78-S78
- Smith, A. F., Hall, P. S., Hulme, Charles, McConkey, Christopher C., Dunn, Janet A., Rahman, J., Mehanna, H., 2016. PET-CT surveillance for advanced head and neck cancer : a cost-effective alternative to planned neck dissection?. Annals of Oncology, Oxford University Press
- Mehanna, H., Wong, W. L., McConkey, Christopher C., Rahman, J. K., Robinson, M., Hartley, A., Nutting, C., Powell, N., Al-Booz, H., Robinson, M., Junor, E., Hulme, C., Smith, A. F., Hall, P., Dunn, Janet A., 2015. Differences in the quality of life (QoL) and functional outcomes of treatment between HPV associated (HPV plus ) and HPV-patients receiving primary chemoradiotherapy in PET-NECK - a multi-centre randomized phase III controlled trial (RCT) comparing PETCT guided active surveillance with planned neck dissection (ND) for locally advanced (N2/N3) nodal metastases (LANM) in patients with head and neck squamous cell cancer (HNC) treated with primary radical chemoradiotherapy (CRT). European Journal of Cancer, Elsevier Science Ltd
- Smith, A. F., Hall, P., Hulme, C., Dunn, Janet A., Rahman, J. K., McConkey, Christopher C., Mehanna, H., 2015. Is PET-CT guided management for patients with locally advanced head and neck squamous cell cancer (HNSCC) cost-effective? Results from a UK non-inferiority phase III randomized trial. Journal of Clinical Oncology, American Society of Clinical Oncology, pp. 6010-6010
- Mehanna, H. M., Wong, W. L., McConkey, Christopher C., Rahman, J. K., Robinson, M., Hartley, A. G. J., Nutting, C., Powell, N., Al-Booz, H., Robinson, M., Junor, E., Hulme, C., Smith, A. F., Hall, P., Dunn, Janet A., 2015. PET-NECK: A multi-centre, randomized, phase III, controlled trial (RCT) comparing PETCT guided active surveillance with planned neck dissection (ND) for locally advanced (N2/N3) nodal metastases (LANM) in patients with head and neck squamous cell cancer (HNSCC) treated with primary radical chemoradiotherapy (CRT). Journal of Clinical Oncology, American Society of Clinical Oncology, pp. 6009-6009
- McCaul, J. A., Pendrill, A., Quantrill, J., Mehanna, H., McConkey, Christopher C., Dunn, Janet A., 2013. LIHNCS trial (Lugol's iodine in head and neck cancer surgery) : Interim recruitment and data report. Oral Oncology, Elsevier BV, pp. S37-S37
- Weller, M. D., Nankivell, Paul C., McConkey, Christopher C., Paleri, Vinidh, Mehanna, Hisham M., 2010. The risk and interval to malignancy of patients with laryngeal dysplasia ; a systematic review of case series and meta-analysis. Clinical Otolaryngology, Wiley-Blackwell Publishing Ltd, pp. 364-372
- Gray, Richard, McConkey, Christopher C., 2008. Adjuvant chemotherapy for rectal cancer ? Authors' reply. Lancet, The Lancet Publishing Group
- Kerr, David J., Dunn, Janet A., Langman, Michael J., Smith, J. L., Midgley, Rachel S. J., Iveson, Claire, McConkey, Christopher C., 2008. VICTOR : a phase III placebo-controlled trial of rofecoxib in colorectal cancer patients following surgical resection. Journal of Clinical Oncology, American Society of Clinical Oncology
- Isles, M. G., McConkey, Christopher C., Mehanna, Hisham M., 2008. A systematic review and meta-analysis of the role of positron emission tomography in the follow up of head and neck squamous cell carcinoma following radiotherapy or chemoradiotherapy. Clinical Otolaryngology, Wiley-Blackwell Publishing Ltd, pp. 210-222
| Title | Funder | Award start | Award end |
|---|---|---|---|
| PET NECK Data Re-Analysis | University of Birmingham | 01 Feb 2017 | 31 Dec 2020 |
| De-escalate - Extension and supplement | Cancer Research UK | 01 Sep 2017 | 31 Dec 2019 |
| Late Phase Study De-ESCALaTE-HPV Determination of Epidermal growth factor receptor-inhibitor(cetuximab) vs Standard Chemotherapy early and late toxicity Events - Year 6 | Cancer Research UK | 01 Sep 2016 | 31 Aug 2017 |
| De-ESCALaTE-HPV - TrialDetermination of epidermal growth factor receptor-inhibitor (cetuximab) vs standard chemotherapy early and late toxicity events in human papilloma virus positive oropharyngeal carcinoma | Cancer Research UK | 01 Mar 2011 | 28 Feb 2017 |
| Lugols Iodine in Head and Neck Cancer Surgery: A multi-centre randomised controlled trial assessing the effectiveness of Lugols Iodine - 15mth extension to the LIHNCS study. | Cancer Research UK | 01 Oct 2014 | 31 Dec 2015 |
| CRUK:via Bradford LUGOLS | Cancer Research UK | 01 Apr 2010 | 31 Mar 2014 |
| HTA SARAH: Strengthening and Stretching for People with Rheumatoid Arthritis of the Hands: The Clinical and Cost Effectiveness of an Exercise Programme Over and Above Usual Care | National Institute for Health Research (DoH) | 01 Sep 2008 | 28 Feb 2012 |