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Dr Tinevimbo Shiri

Job Title
Research Fellow
WMS - Warwick Clinical Trials Unit
Research Interests

My interests focus on applying and developing statistical and computational models to better understand the dynamics of infectious pathogens and disease control, and evaluating the effectiveness of health interventions.

Current Research

  1. Reviewing literature on the impact of childhood pneumococcal conjugate vaccines on the epidemiology of pneumococcal carriage and disease (see our Review on the indirect effects of paediatric pneumococcal conjugate vaccines on invasive pneumococcal disease, with author supplied Supplementary Appendix and Supplementary Table of Study Characteristics).
  2. Developing nuanced transmission models of pneumococcal carriage and disease, pneumococcal disease hospitalisations and assessing the cost-effectiveness of different vaccination strategies

Previous Research

  1. Quantifying respiratory syncytial virus infection kinetics from in vitro and in vivo infections, and determining antiviral efficacy from clinical trials data
  2. Modelling pneumococcal carriage transmission between mother-child pairs and assessing the impact of childhood pneumococcal conjugate vaccines on pneumococcal carriage transmission trends in rural and urban households

See Publications

  1. Pubmed
  2. Google Scholar
  3. ResearchGate

Tinevimbo joined the Warwick Medical School - Clinical Trials Unit in July 2015, having previously worked in the Respiratory and Meningeal Pathogens Research Unit (RMPRU) at the University of the Witwatersrand, South Africa and in the Physical Modelling in Biology, Immunology and Ecology (PHYMBIE) research group at Ryerson University, Toronto, Canada. He was awarded his PhD in Computational and Applied Mathematics in 2011 from the University of the Witwatersrand. His current role within the Clinical Trials Unit is to undertake intensive research on the cost-effectiveness of interventions targeted at infectious diseases in England (see MEMVIE (Mathematical & Economic Modelling for Vaccination and Immunisation Evaluation) projects). He jointly works with a multidisciplinary team of modellers (Profs. Matt J. Keeling and Graham Medley), health economists (Profs. Stavros Petrou and Jason Madan), systematic reviewers (Drs. Pamela Royle and Alex Tsertsvadze ), and epidemiologists (Prof. Noel McCarthy).