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Karuna Sampath



Associate Professor


WMS - Cell and Development Biology
University of Warwick
Tel: (0) 24 76573412

Research Interests

The Sampath laboratory is interested in understanding the mechanisms that control embryonic development and differentiation, and in elucidating the molecular functions of factors that participate in these processes. In particular, we are investigating the roles and regulation of RNA and protein factors in early development, using zebrafish embryos and human uterine stem cells as experimental systems. We use a combination of imaging, proteomic, genetic, genomic, and cell & developmental approaches (see Lim et al., Development 2012; Tran et al., Development 2012, and Kumari et al., eLife, 2013; Lim et al., Genome Biology, 2013). Our current research focuses on the following themes: 1) Roles and regulation of non-coding maternal nodal RNA 2) Microtubule polarity and RNA transport, 3) Regulation of nodal signalling by RNA elements and translational control, and 4) human foetal and maternal disorders associated with RNA elements and RNA-binding factors.


Karuna Sampath is an Associate Professor of Biomedicine, University of Warwick. Following her doctoral training at Indiana State University, USA with Gary Stuart, she did brief post-doctoral stints with Christopher Wright at Vanderbilt University, Nashville, USA (1995-1996), and Vladimir Korzh at the Institute of Molecular Agrobiology, Singapore (1997-1998). She was a visiting scientist at EMBL (host: Anne Ephrussi) in 1999, and started her independent programme in 2000 as a fellow at the Institute of Molecular Agrobiology, Singapore. She was a group leader at Temasek Life Sciences Laboratory, National University of Singapore from 2002-2013. The Sampath lab is located on the Gibbett Hill campus of the University of Warwick, and is funded by Warwick Medical School and the BBSRC.

Research Projects

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