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Karuna Sampath

Job Title
WMS - Biomedical Sciences
(0) 24 76573412
Research Interests

The Sampath laboratory is interested in understanding how embryonic development and differentiation are controlled. We investigate the molecular functions of factors that participate in these processes using zebrafish embryos as the primary experimental system. In particular, we are investigating the roles and regulation of RNA and protein factors, and morphogen signalling in early development. We combine live imaging, proteomic, genetic, genomic, and cell & developmental approaches (Tran et al., Development 2012, Kumari et al., eLife, 2013; Lim et al., Genome Biology, 2013; Wang et al., eLife 2016; Zaucker et al., NAR, 2018; Vong et al., 2020). Our current research focuses on the following themes: 1) Regulation of Nodal morphogen signalling 2) Cytoskeletal organisation and function 3) RNA elements in development and disease


Karuna Sampath is a Professor of Biomedicine, University of Warwick. Following her doctoral training at Indiana State University, USA with Gary Stuart, she did brief post-doctoral stints with Christopher Wright at Vanderbilt University, Nashville, USA (1995-1996), and Vladimir Korzh at the Institute of Molecular Agrobiology, Singapore (1997-1998). She was a visiting scientist in Anne Ephrussi's lab at EMBL in 1999, and started her independent programme in 2000 as a fellow at the Institute of Molecular Agrobiology, Singapore. She was a group leader at Temasek Life Sciences Laboratory, National University of Singapore from 2002-2013. The Sampath lab is located on the Gibbett Hill campus of the University of Warwick. The group is funded by Warwick Medical School, Warwick Quantitative Biomedicine Programme, the BBSRC and the Leverhulme Trust. Karuna Sampath serves on the board of the European Zebrafish society and the International Zebrafish society. She is an Associate editor for the GSA journal Genetics, and serves on the Editorial Board of the Journal of Molecular and Cell Biology.

Title Funder Award start Award end
**COVID-19** Does the Furin 3'UTR control susceptibility to SARS-CoV2? Medical and Life Sciences Research Fund 01 Jan 2021 30 Jun 2022
Probing the Role of Actin Arginylation Through Synthetic Biology BBSRC 01 Dec 2018 30 Nov 2021
Leverhulme Extension COVID to record 55736 Leverhulme Trust 01 May 2021 31 Jul 2021
BBSRC equipment MPFLIM BBSRC 10 Nov 2020 09 Jun 2021
Leverhulme Project Grant (Full) - Understanding the basis of sex bias (Outline: 53644) Leverhulme Trust 01 May 2018 31 Mar 2021
Sampath project grant: Functional RNAs in Axis Formation BBSRC 01 Jan 2014 04 Nov 2017
Funding request for 3rd Warwick Quantitative Biomedicine Symposium: "The Epigenome: Mechanisms of Maintenance". Company of Biologists, The 01 Apr 2017 30 Sep 2017
Sizhou Huang application to the Royal Society Internatonal Fellowship. Royal Society 01 Feb 2015 31 Jan 2017