News Library
Misread heart muscle gene a new clue to risk of sudden cardiac death
Scientists have discovered that a drug which increases the risk of sudden cardiac death interacts with mistranslated protein-coding genes present in heart muscle. Joint work by researchers in the Department of Chemistry, Warwick Medical School and at the SEEK drug discovery group, just published in the Royal Society of Chemistry journal Chemical Communications, shows that flecainide appears to interact with just such an ARF protein, the "normal" version of which is crucial to heart function.