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New RSC video explains 'Team Ice's' award-winning research

The work of 'Team Ice' has been brought to life in a new RSC-commissioned videoLink opens in a new window celebrating their Chemistry Biology Interface Division Horizon Prize, 2022.

Tue 30 May 2023, 16:21 | Tags: news ChemBio Research news Impact

New Warwick research is helping scientists preserve cells

New technology, covered in JACS AuLink opens in a new window, could improve the cryopreservation of cells, tissue culture and 3D cells models used in a variety of applications, including research, medical therapies and agriculture. Read moreLink opens in a new window

Tue 02 May 2023, 11:10 | Tags: news MatPolymers ChemBio Research news

New Method to Cryopreserve 3D Tissue Models

Liver cell spheroids are cryopreserved using macromolecular cryoprotectants, which will enable their easy banking and sharing. Read more..;

Mon 09 Jan 2023, 11:36 | Tags: news MatPolymers ChemBio Research news Impact

Matt Jenner wins £1.25 million UKRI Future Leaders Funding

Dr Matthew Jenner in the University’s Department of Chemistry has received £1.25 million for the project ‘Dissecting and Harnessing Carrier Protein Interactions in Fungal Megasynth(et)ases’. Read moreLink opens in a new window

Wed 15 Jun 2022, 15:55 | Tags: news ChemBio Research news

Production Polysaccharides at the Cell Surface

The Stansfeld groupLink opens in a new window, in SLS and Chemistry, have published two papers in the journal Nature on the production of polysaccharides around cells.

Wed 04 May 2022, 14:45 | Tags: news MeasMod ChemBio Research news

GibsonGroup COVID-19 work in Medical School Council Report

The Medical Schools Council today published a report showcasing the work from UK Universities during the COVID-19 Pandemic, including from the GibsonGroup

Wed 15 Dec 2021, 15:31 | Tags: news people ChemBio Research news Impact

Congratulations to Prize-winner, Dr Christine Lockey

Congratulations go to Dr Christine Lockey, who has been announced as a Faculty Post-Doctoral Research Prize winner for “Best Warwick affiliated research output in 2020”.

Fri 21 May 2021, 17:14 | Tags: news people ChemBio Research news Women in Chemistry

Solving the puzzle of polymer-ice binding for cryopreservation

When biological material is frozen, cryoprotectants are used to prevent ice damage. How do newly emerging polymeric cryoprotectants control ice formation and growth during freezing?

Soil bacteria hormone discovery provides fertile ground for new antibiotics

The discovery of how hormone-like molecules turn on antibiotic production in soil bacteria could unlock the untapped opportunities for medicines that are under our very feet.

An international team of scientists working in the Department of Chemistry, the School of Life Sciences and the Warwick Integrative Synthetic Biology Centre at the University of Warwick, UK, and Monash University, Australia, have determined the molecular basis of a biological mechanism that could enable more efficient and cost-effective production of existing antibiotics, and also allow scientists to uncover new antibiotics in soil bacteria.

It is detailed in a new study published in the journal Nature.

Thu 11 Feb 2021, 08:23 | Tags: publications ChemBio Research news

New company, CryoLogyx, is spun out from the Department

A new biotechnology company, CryoLogyx, has been spun-out from the department, supported from a grant from InnovateUK. Cryologyx will be led by Dr Tom Congdon (A UoW UG and PG alumus) and will exploit technology developed by the GibsonGroup. Cryologyx will use innovative macromolecular (polymeric) cryoprotectants to protect biological samples, including cells used in therapy, diagnostics and drug discovery.

Read the news story here and more details will be released soon.

Wed 10 Feb 2021, 14:59 | Tags: news people MatPolymers ChemBio Impact

Dixon Group publishes first molecular description of VanS binding site within vancomycin antibiotic, offering potential in future therapeutic engineering

Resistance has emerged to vancomycin, a last-resort antibiotic for treatment of MRSA. The VanSR regulatory system induces expression of resistance genes upon exposure; however, the mechanism of vancomycin detection was unclear. Through solution NMR and other biophysical methods, we reveal a direct interaction between vancomycin and the extracellular domain of VanS from Streptomyces coelicolor. The VanS-binding epitope within vancomycin was mapped to a region distinct from the binding site for Lipid II. In targeting a separate site, the effective VanS ligand concentration includes both free and lipid-bound molecules, facilitating VanS activation. This is the first molecular description of the VanS/vancomycin interface, and could direct engineering of future therapeutics.

Tue 14 Jul 2020, 12:40 | Tags: ChemBio Research news

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