A recent paper by the GibsonGroup in Chem Commun has been highlighted in the RSC Magazine 'Chemistry World'. The Gibson Group have a research program focussed on mimicking the function of Antifreeze Proteins which are found in Polar fish species. These proteins can slow the rate of ice growth, which has been identified as a challenge in the cryopreservation of donor cells and tissue for transplantation. In this work they showed a facile route to new cryoprotective polymers, using cheap, commodity polymer starting materials. These polymers were shown to have ice growth inhibition activity and to signficantly reduce the ice-induced damage during red blood cell freeze/thaw storage. In a second paper, the group also reported signficantly enhanced cryopreservation using poly(vinyl alcohol).

Read the Chemistry World article here

Read the Chemical Communications article here; Rational, yet simple, design and synthesis of an antifreeze-protein inspired polymer for cellular cryopreservation

Read our recent ACS Biomaterials Science and Enginneering paper here Glycerol Free Cryopreservation of Red Blood Cells Enabled by Ice Recrystallization Inhibiting Polymers

Józef Lewandowski was awarded Anatole Abragam Prize of International Society of Magnetic Resonance "for his outstanding accomplishments to date and his promise in the development of solid-state NMR methodology and its application to the study of biomolecular structure and dynamics." The prize will be presented during ISMAR Conference in Shanghai.

At the Chemistry Departments annual postgraduate symposium, Robert Deller (GibsonGroup) and Athina anastasaki (HaddletonGroup) won the prizes for the best PhD Theses. The Thesis prize is Sponsored by the Faculty of Science.

The Bugg and Gibson groups are involved in 2 new projects intended to promote translation of new technologies. These projects are funded by the Industrial Biocatalyst program supported by Innovate UK, BBSRC and EPSRC and span a range of UK universities and companies.

Dr Matthew Gibson has been awarded the RSC/Dextra Medal for Carbohydrate Science. This award, which is sponsored by Dextra Laboratories, was founded in 1970. It is presented to a scientist in the early/mid stage of their career for meritorious work in carbohydrate chemistry that has largely been conducted in the UK.

Matt will present a lecture, and recieve the medal at the joint RSc/COST MultiglycoNano Meeting in Bangor, Wales, in April.

To read more about the GibsonGroup's research visit their webpage.

3 Academics in the Department have been awarded prestigious ERC starting grants with a total value of almost €5 million. Set up in 2007 by the EU, the European Research Council (ERC) is the first pan-European funding organisation for frontier research. It aims to stimulate scientific excellence in Europe by encouraging competition for funding between the very best, creative researchers of any nationality and age.

Dr Adrian Chaplin will develop new synthetic methodology for studying the interaction of alkanes with transition metals.
Dr Matthew Gibson will study mimics of antifreeze (glyco)proteins with the aim of improving cell cryopreservation.
Dr Józef Lewandowski will develop and apply approaches to investigate structural dynamics of large protein complexes by solid- and solution-state NMR.

These awards bring the total number of ERC-funded researches in the Department to 8, a clear testament to the internationally-leading nature of the research environment at Warwick.

Lewandowski group in collaboration with Grzesiek (Basel, Switzerland) and Samoson (Tallinn, Estonia) groups has introduced a new solid-state NMR based approach that enables quantitative structural and dynamics studies of large protein complexes in a few nanomole quantities. This manuscript signifying a dawn of new era for high resolution NMR studies of large protein complexes has been featured in JACS Spotlights. Read the article in JACS.

The GibsonGroup's recent work on antifreeze-protein mimics has been highlighted on the front cover of RSC Biomaterials Science. http://pubs.rsc.org/en/content/articlelanding/2014/bm/c4bm00153b#!divAbstract

The Gibson's group Cryopreservation research has been highlighted in an article in Chemical and Engineering News. The group are developing a range of macromolecules which mimic the function of antifreeze proteins, found in Polar fish species, which can slow the rate of ice crystal growth. The group have shown these unique polymers to enhance the cryopreservation of donor tissue/cells, particulary blood. (Image is ice crystals which are inhibited by the polymers)Read the article here (Login required) and also the Chemistry World Feature here(login required).

Read Popular Science (USA) article on this here or BBC TV story here.

See publication list for full details.

Supramolecular guanosine-borate hydrogels have been made and characterised in a collaboration led by Jeff Davis (University of Maryland) with Andrew Marsh (Chemistry) and Steven Brown (Physics). The physiologically compatible gels, published in Journal of the American Chemical Society are featured in a Spotlight article. Lead author Gretchen Peters and Jeff Davis will visit Warwick again, 17-21 November to further explore applications of the materials.

Robert Deller, in the GibsonGroup won the prize for the best poster at the 2014 RAPS Conference

Helical arrays of small organic molecules around a core of Fe(II) ions act as highly potent and highly selective anticancer compounds. The work is published in Nature Chemistry.