Biological Inorganic Chemistry

Structure and Dynamics of Metal-binding Proteins

ResearcherIDLink opens in a new window

Our work is concerned with the coordination chemistry of diamagnetic metal ions such as zinc, copper(I), and cadmium in proteins. We are particularly interested in the molecular mechanisms that govern the movements of zinc within whole organisms and within individual cells.

We use NMR and other spectroscopic techniques to study the structure and reactions of metalloproteins. Other techniques that are indispensable in our work are Electrospray Mass Spectrometry and protein expression and purification.

Please use the links below to find out more about our research interests.

Blood plasma proteins involved in zinc transportLink opens in a new window

MetalloproteomicsLink opens in a new window

Metallothioneins: an overviewLink opens in a new window

Bacterial MetallothioneinsLink opens in a new window

Plant MTsLink opens in a new window

Metallothioneins from wormsLink opens in a new window

Histidines in metallothioneinsLink opens in a new window

The group (and alumni) in July 2023 (from left): Caitlin Williams (MChem 2022/23), Claudia Blindauer, Alevtina Mikhaylina (PhD 2019), Pan Prasongpholchai (PDRA 2021/22), Sirilata Polepalli (PDRA 2022 onwards), Lily Fisher (MChem 2022/23). Not in the picture: Azzobir Emhemed (current PhD)