Email: owen dot tooley at warwick dot ac dot uk

AS CDT: 2021-25

PhD Project: Screening and optimisation of active targeted polymeric systems for cancer therapy - In this project, we will screen and optimise the conditions of the conjugation reaction and purification of the active targeted polymeric materials as these factors directly impact the effectiveness and quality of these materials.

MSc Mini-Project 1, Supervisor Professor Jozef Lewandowski: Understanding the Behaviour of PROTACs in bio-relevant media - Using a mixture of different NMR experiments to observe the conformational behaviour of PROTACs in aqueous media that simulates the upper gastrointestinal tract.

MSc Mini-Project 2, Supervisors Dr Paul Wilson and Dr Daniel Lester: Screening and optimisation of active targeted nanomedicines for cancer therapy - Using a combination of techniques including GPC, HPLC, DLS, Zeta-Potential and NMR to synthesise, characterise and investigate processes to synthesise novel dendrimer conjugates.

MChem (Hons) Cardiff University 2021 with year in industry at AstraZeneca working on developing accelerated stability modelling for new modality compounds using RP-HPLC.

MChem project, supervised by Dr Niklaas Buurma, worked on synthesising and characterising different carrier prodrug model systems involving the use of NMR and Mass Spectrometry. Then, comparing and characterising their release kinetics using UV-Visible Spectroscopy and RP-HPLC.

Associate Member of the Royal Society of Chemistry (AMRSC)

Registered Scientist (RSci)