Research interests include:
Mapping protein-protein interactions in biosynthetic systems by structural mass spectrometry.
Mechanisms and engineering of biosynthetic enzymes.
Discovery and biosynthesis of secondary metabolites from Burkholderia sp.
Selected Recent Publications (Google Scholar)
M. Jenner, S. Kosol , D. Griffiths, P. Prasongpholchai, L. Manzi, A.S. Barrow, J.E. Moses, N.J. Oldham, J.R. Lewandowski and G.L. Challis. Mechanism of intersubunit ketosynthase–dehydratase interaction in polyketide synthases.
J. Masschelein, M. Jenner and G.L. Challis. Antibiotics from Gram-negative bacteria: a comprehensive overview and selected biosynthetic highlights.
L. Song, M. Jenner, J. Masschelein, C. Jones, M. Bull, S. Harris, R. Hartkoorn, A. Vocat, I. Romero-Canelón, P. Coupland, Paul, G. Webster, M. Dunn, R. Weiser, C. Paisey, S. Cole, J. Parkhill, E. Mahenthiralingam and G.L. Challis. Discovery and biosynthesis of gladiolin: a Burkholderia gladioli antibiotic with promising activity against Mycobacterium tuberculosis.