Prof Sebastien Perrier
Groups at Warwick
Affiliations
- Chemistry at Warwick University
- Warwick Medical School
- Monash University
Biography
Professor Sebastien Perrier graduated from the Ecole National Supèrieure de Chimie de Montpellier, France, in 1998. He undertook his PhD at the University of Warwick, in polymer chemistry, and spent one year as a postdoctoral fellow at the University of New South Wales, Australia. He started his academic career at Leeds in 2002 as a lecturer, then moved to the University of Sydney in 2007, as director of the Key Centre for Polymers & Colloids. In October 2013, Sebastien was appointed as the Monash-Warwick Chair in Polymer Chemistry, a joint appointment between WMS and Chemistry at Warwick, and the Faculty of Pharmacy at Monash University, Australia. This joint appointment enables Sebastien’s team to have labs and infrastructure in Warwick Chemistry, Warwick Medical School and Monash Pharmacy.
Sebastien has published nine book chapters and over 200 articles, which have received over 15,000 citations (h-index 61), and supervised to date 35 PhD students. His recent awards include the Macro Group UK Young Researcher Award (2006), the Rennie Memorial Medal (2009), the RACI Applied Research Award (2012), a Future Fellowship (2012), the Australian Academy of Science Le Fèvre Memorial Prize (2013), the Wolfson Merit Award (Royal Society, 2014), the Biomacromolecules / Macromolecules Young Investigator Award (ACS, 2014) and the IUPAC / Samsung Young Polymer Scientist Award (IUPAC, 2014), the Macro Group UK Medal (2018).
| 2013-pres | Monash – Warwick Alliance Chair in Polymer Chemistry School of Chemistry, The University of Warwick, UK Monash Institute of Pharmaceutical Sciences, Monash University, Australia |
| 2012-13 | Professor in Chemistry, School of Chemistry, University of Sydney, Australia |
| 2012-13 | ARC Future Fellow |
| 2011-13 | Australian Research Council College Expert, Physics, Chemistry and Earth Sciences (PCE) panel |
| 2007-13 | Director of the Key Centre for Polymers & Colloids, University of Sydney, Australia. |
| 2007-12 | Associate Professor, School of Chemistry, University of Sydney, Australia |
| 2005-07 | Senior Lecturer in Polymer Chemistry, Department of Colour and Polymer Chemistry, University of Leeds, UK. |
| 2002-05 | Lecturer in Polymer Chemistry, Department of Colour and Polymer Chemistry, University of Leeds, UK. |
| 2001-02 | Research Fellow, CAMD, University of New South Wales, Australia. |
Our group are working on the following projects at the moment:
- Fundamental understanding of polymerization mechanisms
- Development of synthetic strategies to make functional polymeric architectures
- Self-assembly via supramolecular interaction
- Engineering of nanostructured materials
- Nanomaterials fro biomedical applications
Our research focuses on the synthesis of macromolecules with highly controlled and pre-determinable structures using modern polymer and organic synthetic methods. We exploit supramolecular interactions to organise these molecules into nanostructured materials, for applications in nanomedicine (e.g. drug delivery, vaccines, antimicrobial materials - our materials are tested in house and in our group at the Monash Institute for Pharmaceutical Sciences (MIPS) in Melbourne, Australia), nanotechnology (e.g. components for optoelectronic applications), materials science (e.g. rheology modifiers) or chemistry (catalysis, processes, etc.).
Sebastien teaches the CH272, CH404 undergraduate module and CH161 Organic Chemistry tutorials, and the CH967 and CH974 MSc modules.
Our group consists of ca. 20 researchers, PhD, Master students, postdoctoral fellows and technicians, across the Department of Chemistry and the Warwick Medical School.
We always have projects available fro PhD and postdoctoral fellows, if you get in touch I'll see if a member of my team might be able to help.
For an up to date list of publications, please visit Google Scholar.
Most representative publications:
1. Brendel, JC.; Sanchis, J; Catrouillet, S; Czuba, E; Chen, MZ; Long, BM; Nowell, C; Johnston, A; Jolliffe, KL; Perrier, S, Secondary Self-Assembly of Supramolecular Nanotubes into Tubisomes and Their Activity on Cells, Angewandte Chemie intl. Ed. 2018, DOI: 10.1002/anie.201808543
2. Larnaudie, S.C.; Sanchis, J; Nguyen, T; Peltier, R; Catrouillet, S; Brendel, J.C.; Porter, C.J.H.; Jolliffe, K.A.; Perrier, S Cyclic peptide-poly(HPMA) nanotubes as drug delivery vectors: In vitro assessment, pharmacokinetics and biodistribution Biomaterials, 2018, DOI:https://doi.org/10.1016/j.biomaterials.2018.03.047
3. Rho, J.Y.; Brendel, J.C.; MacFarlane, L.R.; Mansfield, E.D.H.; Peltier, R.; Rogers, S.; Hartlieb, M.; Perrier, S. Probing the Dynamic Nature of Self-Assembling Cyclic Peptide–Polymer Nanotubes in Solution and in Mammalian Cells, Adv. Funct. Mater. 2017, 1704569 DOI: 10.1002/adfm.201704569
4. Gody, G.; Zetterlund, P.B.; Perrier, S.; Harrisson, S. The limits of precision monomer placement in chain growth polymerization, Nat. Commun. 2016, 7, 10514, 10.1038/ncomms10514.
5. Gody, G.; Robert; D.A.; Maschmeyer, T.; Perrier, S. A New Methodology for Assessing Macromolecular Click Reactions and Its Application to Amine–Tertiary Isocyanate Coupling for Polymer Ligation, J. Am. Chem. Soc. 2016, DOI: 10.1021/jacs.5b11831. Open Access PMCID# PMC4846186
6. Danial, M.; My-Nhi Tran, C.; Jolliffe, K.A. Perrier, S. Thermal Gating in Lipid Membranes Using Thermoresponsive Cyclic Peptide Polymer Conjugates, J. Am. Chem. Soc. 2014, 136 (22), 8018-8026.
7. Danial, M.; My-Nhi Tran, C.; Young, P.G.; Perrier, S.; Jolliffe, K.A. Janus cyclic peptide–polymer nanotubes Nat. Commun., 2013, 4:2780 DOI: 10.1038/ncomms3780. Highlighted in the scientific press.
8. Gody, G.; Maschmeyer, T.; Zetterlund, P.B.; Perrier, S. Rapid and Quantitative One-Pot Synthesis of Sequence-Controlled Polymers by Radical Polymerization, Nat. Commun., 2013, 4:2505 DOI: 10.1038/ncomms3505. Highlighted in Nature Chem, Dec 2013, 5 (12), 990.
9. Semsarilar M.; Perrier, S. ‘Green’ Reversible Addition-Fragmentation Chain-Transfer (RAFT) Polymerization,Nature Chem, 2010, 2, 811-820.
10. Konkolewicz, D.; Gray-Weale, A.; Perrier, S. Hyperbranched Polymers by Thiol-Yne Chemistry, From Small Molecules to Functional Polymers. J. Am. Chem. Soc., 2009, 131 (50), 18075-18077.