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Prof. Mike Shipman


Prof. Mike Shipman

Professor of Synthetic Chemistry

B.Sc., Ph.D. (London), FRSC, CChem



Research Summary

The chemical synthesis of functional organic molecules underpins many key advances in human medicine, crop protection, biotechnology, and material science. Hence, the development of efficient, cost-effective routes to carbon-based molecules is an important, contemporary scientific challenge. Work in the Shipman Group is focused on the development of new methods for the construction of organic compounds alongside a variety of application-driven projects. We are especially interested in new uses of strained (3- and 4- membered) heterocycles.

Selected Publications

Readily Accessible sp3-rich Cyclic Hydrazine Frameworks Exploiting Nitrogen Fluxionality, C. Dean, R. Sundaram, S. Roesner, Carson, G. J. Clarkson, M. Wills, M. Jones, M. Shipman, Chem. Sci. 2020, 11, 1636–1642.

Macrocyclisation of Small Peptides Enabled by Oxetane Incorporation, S. Roesner, S.; G. J. Saunders, I. Wilkening, E. Jayawant, J. V. Geden, P. Kerby, A. M. Dixon, R. Notman, M. Shipman, Chem. Sci. 2019, 10, 2465–2472.

Phyllostictine A: Total Synthesis, Structural Verification and Determination of Substructure Responsible for Plant Growth Inhibition, M. Riemer, V. V. Uzunova, N. Riemer, G. J. Clarkson, N. Pereira, R. Napier, M. Shipman, Chem. Commun. 2018, 54, 7211–7214.

Solid-Phase Synthesis of Oxetane Modified Peptides, J. D. Beadle, A. Knuhtsen, A. Hoose, P. Raubo, A. G. Jamieson, M. Shipman, Org. Lett. 2017, 19, 3303–3306.

Regio- and Stereocontrolled Synthesis of 3-Substituted 1,2-Diazetidines by Asymmetric Allylic Amination of Vinyl Epoxide, R. Sundaram, G. J. Clarkson, M. Shipman, Org. Lett. 2017, 19, 2058–2061.