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Matt Gibson

Professor


Matt GibsonMatt holds a professorship joint between the Department of Chemistry and Warwick Medical School and is a Royal Society Industry Research Fellow. Matt also holds an ERC Starter and (from June 2020) ERC Consolidator Grant. Matt leads the industry (iCASE) Scheme in the MRC-funded Doctoral Training Center.

Matt's research has been supported by BBSRC, EPSRC, MRC, Leverhulme Trust, EU, industry partners, and philanthropic donations. In recognition of his research, Matt has been awarded prizes including the Biomacromolecules/Macromolecules Young Investigator Prize, RSC Dextra Medal, MacroGroupUK Young Researcher's Medal and an RSC Emerging Technology Prize.

M dot I dot Gibson at warwick dot ac dot uk

024 765 24803

Office MAS406

Prof. Matthew Gibson Research Group

Groups at Warwick


Biography

  • 2003, MChem, 1st Class honours, University of Durham, UK
  • 2007, Ph.D in Macromolecular Chemistry, University of Durham UK with Prof Neil Cameron
  • 2007 - 2009, Postdoc in the group of Prof. Harm-Anton Klok EPFL, Switzerland.

  • 2009 - 2012, University of Warwick, Department of Chemistry, SCIRA Research Fellow

  • 2012 - 2015, Assistant Professor,

  • 2015 - 2016, Associate Professor

  • Full Professor 2016 - Personal chair between chemistry and Warwick Medical School

The groups research is supported by EU, UKRI, Industry and Charitable bodies. Each project is not listed here, but current funding includes;

  • Nanocarb Project - large EU consortium investigating how glycosylated nanomaterials can be applied in biomedical areas
  • Specialty Glycans Project. Large UK consortium using enzymes and chemistry to generate new carbohydrate derivatives
  • Royal Society Industry Fellow with GE Healthcare
  • ERC Starter Grant. CRYO_MAT. Investigating how we can use polymer chemistry to mimic antifreeze glycoprotein function
  • ERC Consolidator Grant. ICE_PACK. Developing new tools and methods for the transport of biologic therapies
  • Leverhulme Trust Project grants

The Gibsongroup's research interests span the use of chemical tools to address challenges in glycosciences and biomaterials science. This work is mutli-disciplinary, and the group has dedicated facilities for synthesis, tissue culture, microbiology, and analytical science enabling us to tackle challenging problems. The group has made particular contributions in developing new biomaterials for cell storage and freezing, new glycosylated sensors for the detection and investigation of infection, and methods to covalently modify cell surfaces.

I teach on 2nd Year Polymers (in CH272 Materials Modules) and the Polymer Masters program on CH967 (living polymerisation), CH971 (Polymer Labs) and CH972 (group research project). I also undertake tutorials (organic) and I am developing new content for the Warwick Medical Schools Integrated Science UG program


I am supervising the following PhD students:

  • Alexander Baker. Point of Care Diagnostics based upon glyconanomaterials
  • Alexander Murray. New macromolecular cryoprotectants for cell-based therapies
  • Alice Fayter. Biophysics of cryopreservation
  • Amy Godfrey. Bio-enginnering of Photorhabdus Virulence Cassettes (PI Nick Waterfield)
  • Charlotte Fletcher. Magnetic and responsive nanomaterials
  • Huba Marton. New chemical tools for the biologic cold chain
  • Iain Galpin. New materials and molecules inspired by antifreeze proteins
  • Ioanna Kontopoulou. Polymeric and Colloidal Materials for industry applications
  • Matthew Warren. Computational and experimental studies of ice recrystallisation inhibitors
  • Melissa Ligoria. Mono-disperse glycosylated co-ordination cages for infection detection
  • Ruben Tomas. Biochemical engineering of cell surface
  • Panagiotis Georgiou. New glycosylated nanomaterials
  • Ashfaq Ahmed. Expression and investigation of immune-lectins with glycomaterials

We have vacancies for PhD's each year funded by industry, charity, UKRI and the EU. Get in touch with Prof Gibson if interested

Selected Publications

Stubbs, C., Congdon, TR., Davis, J., Lester, D., Richards, SJ., Gibson, M.I., Macromolecules, 2019, 52, 7603-7612, High-throughput Tertiary Amine De-oxygenated Photopolymerizations for Synthesizing Polymer Libraries,

Tomas, R.M.F., Gibson, M.I., Biomacromolecules, 2019, 20, 2726-2736 Optimization and Stability of Cell-Polymer Hybrids Obtained by ‘Clicking’ Synthetic Polymers to Metabolically-Labeled Cell Surface Glycans

Mitchell, DE., Deller, RC., Fayter, A.E.R., Hasan, M., Gutierrez-Marcos, J., Gibson, M.I., Materials Horizons, 2019, 6, 364 - 368. Ice-Recrystallization Inhibiting Polymers Protect Proteins Against Freeze-Stress and Enable Glycerol-Free Cryostorage

Biggs, C.I., Bailey, T.L., Graham, B., Stubbs, C., Fayter, A., Gibson, M. I., Nature Communications, 2017, 1546., Polymer Mimics of Biomacromolecular Antifreezes.

Graham, B., Bailey, T.L., Healey, J.R., Marcellini, M., Deville, S., Gibson, M. I., Angewandte Chemie, 2017.56, 15941–15944 ;Polyproline is a minimal antifreeze protein mimetic and enhances the cryopreservation of cell monolayers'

Mitchell, D.E., Clarkson,G., Fox,D.J., Kaner, R.A.,Scott, P., Gibson, M.I., Journal of the American Chemical Society, 2017,139, 9835–9838 Antifreeze Protein Mimetic Metallohelices with Potent Ice Recrystallization Inhibition Activity.

Mitchell DE., Lovett JR, Armes SP and Gibson MI, Angewandte Chemie, 2016, 55, 2801 - 2804, "Biomimetic Block Copolymer Worms Combined with an Ice-Inhibiting Polymer Enable Solvent-Free Cryopreservation of Red Blood Cells"

Deller, R.C., Vatish, M., Mitchell, D.A., Gibson, M.I., Nature Communications, 2014, 5, 3244, "Synthetic polymers enable non-vitreous cellular cryopreservation by reducing ice crystal growth during thawing"

 

Full Publication List