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Reviewers for Journals
WRAP: Warwick Research Archive Portal: No conditions. Results ordered -Date Deposited.
Tebbe, Dennis Alexander, Gruender, Charlotte Rose, Dlugosch, Leon, Lõhmus, Kertu, Rolfes, Sönke, Könneke, Martin, Chen, Yin, Engelen, Bert and Schäfer, Hendrik (2023) Microbial drivers of DMSO reduction and DMS-dependent methanogenesis in saltmarsh sediments. ISME Journal, 17 . pp. 2340-2351. doi:10.1038/s41396-023-01539-1
ISSN 1751-7362.
09:06, Wed 25 Oct 2023
Ghosh, Devanita, Whitworth, David E., Schäfer, Hendrik, Krishnamurthi, Srinivasan and Saha, Pradipta (2022) Editorial : Microbial mitigation of hazardous compounds in agro-ecosystems. Frontiers in Microbiology, 13 . 1015111. ISSN 1664-302X doi:10.3389/fmicb.2022.1015111
13:23, Wed 30 Nov 2022
Knowlton, Nancy, Mock, Thomas, Boulton, William, Balmonte, John-Paul, Barry, Kevin, Bertilsson, Stefan, Bowman, Jeff, Buck, Moritz, Bratbak, Gunnar, Chamberlain, Emelia J. et al. <#> (2022) Multiomics in the central Arctic Ocean for benchmarking biodiversity change. PLoS Biology, 20 (10). e3001835. ISSN 1545-7885 doi:10.1371/journal.pbio.3001835
16:28, Tue 8 Nov 2022
Kröber, Eileen, Mankowski, Anna and Schäfer, Hendrik (2022) Microorganisms associated with Sporobolus anglicus, an invasive dimethylsulfoniopropionate producing salt marsh plant, are an unrecognized sink for dimethylsulfide. Frontiers in Microbiology, 13 . 950460. doi:10.3389/fmicb.2022.950460
ISSN 1664-302X.
15:24, Fri 4 Nov 2022
Tebbe, Dennis Alexander, Geihser, Simone, Wemheuer, Bernd, Daniel, Rolf, Schäfer, Hendrik and Engelen, Bert (2022) Seasonal and zonal succession of bacterial communities in North Sea salt marsh sediments. Microorganisms, 10 (5). e859. doi:10.3390/microorganisms10050859
ISSN 2076-2607.
12:36, Thu 5 May 2022
Wang, Jing, Chu, Yi-Xuan, Schäfer, Hendrik, Tian, Guangming and He, Ruo (2022) CS2 increasing CH4-derived carbon emissions and active microbial diversity in lake sediments. Environmental Research, 208 . 112678. doi:10.1016/j.envres.2022.112678
ISSN 0013-9351.
11:17, Thu 27 Jan 2022
Palmer, Jess, Hilton, Sally, Picot, Emma, Bending, G. D. and Schäfer, Hendrik (2021) Tree phyllospheres are a habitat for diverse populations of CO-oxidizing bacteria. Environmental Microbiology, 23 (10). pp. 6309-6327. doi:10.1111/1462-2920.15770
ISSN 1462-2912.
14:26, Tue 28 Sep 2021
Picot, Emma, Hale, Chris C., Hilton, Sally, Teakle, Graham R., Schäfer, Hendrik, Huang, Yong-Ju, Perryman, Sarah, West, Jon S. and Bending, G. D. (2021) Contrasting responses of rhizosphere bacterial, fungal, protist, and nematode communities to nitrogen fertilization and crop genotype in field grown oilseed rape (Brassica napus). Frontiers in Sustainable Food Systems, 5 . 613269. doi:10.3389/fsufs.2021.613269
ISSN 2571-581X.
15:26, Wed 21 Apr 2021
Cook, Sarah, Price, Oliver, King, Andrew, Finnegan, Chris, van Egmond, Roger, Schäfer, Hendrik, Pearson, Jonathan M., Abolfathi, Soroush and Bending, G. D. (2020) Bedform characteristics and biofilm community development interact to modify hyporheic exchange. Science of The Total Environment, 749 . 141397. doi:10.1016/j.scitotenv.2020.141397
ISSN 0048-9697.
12:57, Thu 13 Aug 2020
Cook, Sarah, Chan, Hui-Ling, Abolfathi, Soroush, Bending, G. D., Schäfer, Hendrik and Pearson, Jonathan M. (2020) Data for Longitudinal dispersion of microplastics in aquatic flows using fluorometric techniques. [Dataset]
10:18, Mon 20 Jul 2020
Dixon, Joanna L., Hopkins, Frances E., Stephens, John A. and Schäfer, Hendrik (2020) Seasonal changes in microbial dissolved organic sulfur transformations in coastal waters. Microorganisms, 8 (3). e337. doi:10.3390/microorganisms8030337
ISSN 2076-2607.
14:08, Tue 10 Mar 2020
Schäfer, Hendrik and Eyice, Özge (2019) Microbial cycling of methanethiol. Current Issues in Molecular Biology, 33 . pp. 173-182. doi:10.21775/CIMB.033.173
ISSN 14673037.
16:47, Tue 25 Feb 2020
Cook, Sarah, Chan, Hui-Ling, Abolfathi, Soroush, Bending, G. D., Schäfer, Hendrik and Pearson, Jonathan M. (2020) Longitudinal dispersion of microplastics in aquatic flows using fluorometric techniques. Water Research, 170 . 115337. doi:10.1016/j.watres.2019.115337
ISSN 0043-1354.
12:32, Wed 11 Dec 2019
Chen, Yin and Schäfer, Hendrik (2019) Towards a systematic understanding of structure–function relationship of dimethylsulfoniopropionate‐catabolizing enzymes. Molecular Microbiology, 111 (6). pp. 1399-1403. doi:10.1111/mmi.14230
ISSN 0950-382X.
10:24, Fri 12 Apr 2019
Veras, Dimitri, Armstrong, David J., Blake, James A., Gutierrez-Marcos, José F., Jackson, Alan P. and Schäfer, Hendrik (2018) Dynamical and biological panspermia constraints within multi-planet exosystems. Astrobiology, 18 (9). pp. 1106-1122. doi:10.1089/ast.2017.1786
ISSN 1531-1074.
15:19, Wed 14 Feb 2018
Pol, Arjan, Renkema, G. Herma, Tangerman, Albert, Winkel, Edwin G., Engelke, Udo F., Brouwer, Arjan P. M. de, Lloyd, Kent C., Araiza, Renee S., Heuvel, Lambert van den , Omran, Heymut et al. <#> (2018) Mutations in SELENBP1, encoding a novel human methanethiol oxidase, cause extraoral halitosis. Nature Genetics, 50 (1). pp. 120-129. doi:10.1038/s41588-017-0006-7
ISSN 1061-4036.
16:39, Thu 21 Dec 2017
Eyice, Özge, Myronova, Natalia, Pol, Arjan, Carrion, Ornella, Todd, Jonathan, Smith, Tom J., Gurman, Stephen J., Cuthbertson, Adam, Mazard, Sophie, Mennink-Kersten, Monique A. S. H. , Bugg, Tim, Andersson, K. Kristoffer, Johnston, Andrew W. B., Op Den Camp, Huub J. M. and Schäfer, Hendrik (2018) Bacterial SBP56 identified as a Cu-dependent methanethiol oxidase widely distributed in the biosphere. ISME Journal, 12 (1). 145-160 . doi:10.1038/ismej.2017.148
ISSN 1751-7362.
14:14, Tue 8 Aug 2017
Kowalczyk, Agnieszka, Price, Oliver R., van der Gast, Christopher J., Finnegan, Christopher J., van Egmond, Roger A., Schäfer, Hendrik and Bending, G. D. (2016) Spatial and temporal variability in the potential of river water biofilms to degrade p-nitrophenol. Chemosphere, 164 . pp. 355-362. doi:10.1016/j.chemosphere.2016.08.095
ISSN 0045-6535.
08:28, Tue 18 Oct 2016
Zhu, Yijun , Ksibe, Amira Z., Schäfer, Hendrik, Blindauer, Claudia A., Bugg, Tim and Chen, Yin (2016) O2-independent demethylation of trimethylamine N-oxide by Tdm of Methylocella silvestris. FEBS Journal, 283 (21). pp. 3979-3993. doi:10.1111/febs.13902
ISSN 1742-464X.
14:52, Mon 19 Sep 2016
Lidbury, Ian, Kröber, Eileen, Zhang, Zhidong, Zhu, Yijun , Murrell, J. C. (J. Colin), Chen, Yin and Schäfer, Hendrik (2016) A mechanism for bacterial transformation of dimethylsulfide to dimethylsulfoxide : a missing link in the marine organic sulfur cycle. Environmental Microbiology, 18 . pp. 2754-2766. doi:10.1111/1462-2920.13354
ISSN 1462-2912.
08:41, Mon 25 Apr 2016
Eyice, Özge and Schäfer, Hendrik (2016) Culture-dependent and culture-independent methods reveal diverse methylotrophic communities in terrestrial environments. Archives of Microbiology, 198 (1). pp. 17-26. doi:10.1007/s00203-015-1160-x
ISSN 0302-8933.
10:56, Fri 6 Nov 2015
Kappler, U. and Schäfer, Hendrik (2014) Transformations of dimethylsulfide. In: Kroneck, Peter M. H. and Sosa Torres, Martha E., (eds.) The Metal-Driven Biogeochemistry of Gaseous Compounds in the Environment. Metal Ions in Life Sciences, 14 . Springer Netherlands, pp. 279-313. ISBN 9789401792684
09:55, Tue 11 Aug 2015
Kowalczyk, Agnieszka, Martin, Timothy James, Price, Oliver Richard, Snape, Jason, van Egmond, Roger Albert, Finnegan, Christopher James, Schäfer, Hendrik, Davenport, Russell James and Bending, G. D. (2015) Refinement of biodegradation tests methodologies and the proposed utility of new microbial ecology techniques. Ecotoxicology and Environmental Safety, 111 . pp. 9-22. doi:10.1016/j.ecoenv.2014.09.021
ISSN 0147-6513.
09:39, Tue 11 Aug 2015
Kowalczyk, Agnieszka, Eyice, Özge, Schäfer, Hendrik, Price, Oliver R, Finnegan, Christopher J., van Egmond, Roger A., Shaw, Liz J., Barrett, Glyn and Bending, G. D. (2015) Characterization of para-nitrophenol degrading bacterial communities in river water using functional markers and stable isotope probing. Applied and Environmental Microbiology, 81 (19). pp. 6890-6900. AEM.01794-15. doi:10.1128/AEM.01794-15
ISSN 0099-2240.
09:33, Tue 11 Aug 2015
Eyice, Özge, Namura, Motonobu, Chen, Yin, Mead, A. (Andrew), Samavedam, Siva and Schäfer, Hendrik (2015) SIP metagenomics identifies uncultivated Methylophilaceae as dimethylsulphide degrading bacteria in soil and lake sediment. The ISME Journal, 9 . pp. 2336-2348. doi:10.1038/ismej.2015.37
ISSN 1751-7362.
13:46, Mon 15 Jun 2015
Mazard, Sophie and Schäfer, Hendrik (2014) Stable isotope probing to study functional components of complex microbial ecosystems. In: Paulsen, Ian T. and Holmes, Andrew J., (eds.) Environmental Microbiology. Methods in Molecular Biology, Volume 1096 . Humana Press, pp. 169-180. ISBN 9781627037112
13:54, Fri 1 May 2015
Chan, Jacqueline, Millard, Andrew D., Mann, Nicholas H. and Schäfer, Hendrik (2014) Comparative genomics defines the core genome of the growing N4-like phage genus and identifies N4-like Roseophage specific genes. Frontiers in Microbiology, Volume 5 . Article number 506. doi:10.3389/fmicb.2014.00506
ISSN 1664-302X.
09:17, Tue 14 Oct 2014
Zhu, Yijun , Jameson, Eleanor, Parslow, Rosemary A., Lidbury, Ian, Fu, Tiantian, Dafforn, Tim, Schäfer, Hendrik and Chen, Yin (2014) Identification and characterization of trimethylamine N-oxide (TMAO) demethylase and TMAO permease in Methylocella silvestris BL2. Environmental Microbiology, 16 (10). pp. 3318-3330. doi:10.1111/1462-2920.12585
ISSN 1462-2912.
10:27, Wed 13 Aug 2014
Davies, Lawrence O., Bramke, Irene, France, Emma, Marshall, Samantha, Oliver, Robin, Nichols, Carol, Schäfer, Hendrik and Bending, G. D. (2013) Non-UV light influences the degradation rate of crop protection products. Environmental Science & Technology, Volume 47 (Number 15). p. 130712083104003. doi:10.1021/es402139x
ISSN 0013-936X.
11:32, Thu 27 Mar 2014
Zhu, Yijun , Jameson, Eleanor, Cosatti, Marialuisa , Schäfer, Hendrik, Rajakumar, Kumar , Bugg, Tim and Chen, Yin (2014) Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota. Proceedings of the National Academy of Sciences of the United States of America, 111 (11). pp. 4268-4273. doi:10.1073/pnas.1316569111
ISSN 0027-8424.
12:41, Fri 31 Jan 2014
Davies, Lawrence O., Schäfer, Hendrik, Marshall, Samantha, Bramke, Irene, Oliver, Robin G. and Bending, G. D. (2013) Light structures phototroph, bacterial and fungal communities at the soil surface. PLoS One, Volume 8 (Number 7). Article number e69048. doi:10.1371/journal.pone.0069048
ISSN 1932-6203.
14:56, Mon 29 Jul 2013
Cox, Michael J., Schäfer, Hendrik, Nightingale, Phillip D., McDonald, Ian R. and Murrell, J. C. (J. Colin) (2012) Diversity of methyl halide-degrading microorganisms in oceanic and coastal waters. FEMS Microbiology Letters, Vol.334 (No.2). pp. 111-118. doi:10.1111/j.1574-6968.2012.02624.x
ISSN 03781097.
09:41, Mon 10 Sep 2012
Boden, Rich, Ferriera, S., Johnson, J., Kelly, Donovan P., Murrell, J. C. (J. Colin) and Schäfer, Hendrik (2011) Draft genome sequence of the chemolithoheterotrophic, halophilic methylotroph methylophaga thiooxydans DMS010. Journal of Bacteriology, Vol.193 (No.12). pp. 3154-3155. doi:10.1128/JB.00388-11
ISSN 0021-9193.
10:38, Wed 30 Nov 2011
Boden, Rich, Murrell, J. C. (J. Colin) and Schäfer, Hendrik (2011) Dimethylsulfide is an energy source for the heterotrophic marine bacterium Sagittula stellata. FEMS Microbiology Letters, Vol.322 (No.2). pp. 188-193. doi:10.1111/j.1574-6968.2011.02349.x
ISSN 0378-1097.
15:42, Mon 17 Oct 2011
Purification and characterization of dimethylsulfide monooxygenase from hyphomicrobium sulfonivorans
Boden, Rich, Borodina, E., Wood, A. P., Kelly, Donovan P., Murrell, J. C. (J. Colin) and Schäfer, Hendrik (2011) Purification and characterization of dimethylsulfide monooxygenase from hyphomicrobium sulfonivorans. Journal of Bacteriology, Vol.193 (No.5). pp. 1250-1258. doi:10.1128/JB.00977-10
ISSN 0021-9193.
13:13, Wed 10 Aug 2011
Schäfer, Hendrik (2007) Isolation of Methylophaga spp. from marine dimethylsulfide-degrading enrichment cultures and identification of polypeptides induced during growth on dimethylsulfide. Applied and Environmental Microbiology, Vol.73 (No.8). pp. 2580-2591. doi:10.1128/AEM.02074-06
ISSN 0099-2240.
15:59, Wed 20 Apr 2011
Neufeld, Josh D., Schäfer, Hendrik, Cox, Michael J., Boden, Rich, McDonald, Ian R. and Murrell, J. C. (J. Colin) (2007) Stable-isotope probing implicates Methylophaga spp and novel Gammaproteobacteria in marine methanol and methylamine metabolism. ISME Journal, Vol.1 (No.6). pp. 480-491. doi:10.1038/ismej.2007.65
ISSN 1751-7362.
15:49, Wed 20 Apr 2011
Schaefer, Hendrik, Ferdelman, Timothy G., Fossing, Henrik and Muyzer, Gerard (2007) Microbial diversity in deep sediments of the Benguela Upwelling System. Aquatic Microbial Ecology, Vol.50 (No.1). pp. 1-9. doi:10.3354/ame01164
ISSN 0948-3055.
15:37, Wed 20 Apr 2011
Cunliffe, Michael, Schaefer, Hendrik, Harrison, E. (Emma), Cleave, Simon, Upstill-Goddard, R. C. (Robert C.) and Murrell, J. C. (J. Colin) (2008) Phylogenetic and functional gene analysis of the bacterial and archaeal communities associated with the surface microlayer of an estuary. ISME Journal, Volume 2 (Number 7). pp. 776-789. doi:10.1038/ismej.2008.28
ISSN 1751-7362.
15:20, Wed 20 Apr 2011
Cunliffe, Michael, Harrison, Emma, Salter, Matthew, Schaefer, Hendrik, Upstill-Goddard, Robert C. and Murrell, J. C. (J. Colin) (2009) Comparison and validation of sampling strategies for the molecular microbial analysis of surface microlayers. Aquatic Microbial Ecology, Vol.57 (No.1). pp. 69-77. doi:10.3354/ame01330
ISSN 0948-3055.
12:52, Wed 20 Apr 2011
Latypova, Ekaterina, Yang, Song, Wang, Yi-Shun, Wang, Tiansong, Chavkin, Theodore A., Hackett, Murray, Schaefer, Hendrik and Kalyuzhnaya, Marina G. (2010) Genetics of the glutamate-mediated methylamine utilization pathway in the facultative methylotrophic beta-proteobacterium Methyloversatilis universalis FAM5. Molecular Microbiology, Vol.75 (No.2). pp. 426-439. doi:10.1111/j.1365-2958.2009.06989.x
ISSN 0950-382X.
12:42, Wed 20 Apr 2011
Chen, Yin, Scanlan, Julie, Song, Lijiang, Crombie, Andrew, Rahman, M. Tanvir, Schäfer, Hendrik and Murrell, J. C. (J. Colin) (2010) Gamma-Glutamylmethylamide Is an Essential Intermediate in the Metabolism of Methylamine by Methylocella silvestris. Applied and Environmental Microbiology, Vol.76 (No.13). pp. 4530-4537. doi:10.1128/AEM.00739-10
ISSN 0099-2240.
10:56, Wed 20 Apr 2011
Boden, Rich, Kelly, Donovan P., Murrell, J. C. (J. Colin) and Schäfer, Hendrik (2010) Oxidation of dimethylsulfide to tetrathionate by Methylophaga thiooxidans sp. nov.: a new link in the sulfur cycle. Environmental Microbiology, Vol.12 (No.10). pp. 2688-2699. doi:10.1111/j.1462-2920.2010.02238.x
ISSN 1462-2912.
10:50, Wed 20 Apr 2011
Cunliffe, Michael, Whiteley, Andrew S., Newbold, Lindsay, Oliver, Anna, Schäfer, Hendrik and Murrell, J. C. (J. Colin) (2009) Comparison of bacterioneuston and bacterioplankton dynamics during a phytoplankton bloom in a fjord mesocosm. Applied and Environmental Microbiology, Vol.75 (No.22). pp. 7173-7181. doi:10.1128/AEM.01374-09
ISSN 0099-2240.
11:40, Tue 5 Oct 2010
Schäfer, Hendrik, Myronova, Natalia and Boden, Rich (2010) Microbial degradation of dimethylsulphide and related C1-sulphur compounds: organisms and pathways controlling fluxes of sulphur in the biosphere. Journal of Experimental Botany, Vol.61 (No.2). pp. 315-334. doi:10.1093/jxb/erp355
ISSN 0022-0957.
14:38, Tue 13 Apr 2010
Neufeld, Josh D. , Boden, Rich, Moussard, Hélène, Schäfer, Hendrik and Murrell, J. C. (J. Colin) (2008) Substrate-specific clades of active marine methylotrophs associated with a phytoplankton bloom in a temperate coastal environment. Applied and Environmental Microbiology, Vol.74 (No.23). pp. 7321-7328. doi:10.1128/AEM.01266-08
ISSN 0099-2240.
12:20, Thu 8 Jan 2009
Kröber, Eileen and Schäfer, Hendrik (2019) Identification of proteins and genes expressed by Methylophaga thiooxydans during growth on dimethylsulfide and their presence in other members of the genus. Frontiers in Microbiology, 10 . 1132. doi:10.3389/fmicb.2019.01132
ISSN 1664-302X.
10:18, Fri 24 May 2019
- Nygaard, Rie, Graham, Chris L. B., Belcher Dufrisne, Meagan, Colburn, Jonathan D., Pepe, Joseph, Hydorn, Molly A., Corradi, Silvia, Brown, Chelsea M., Ashraf, Khuram U., Vickery, Owen N., Briggs, Nicholas, Deering, John, Kloss, Brian, Botta, Bruno, Clarke, Oliver B., Columbus, Linda, Dworkin, Jonathan, Stansfeld, Phillip J., Roper, David I., Mancia, Filippo, 2023. Structural basis of peptidoglycan synthesis by E. coli RodA-PBP2 complex. Nature Communications, 14 (1)
- Graham, Chris L. B., Bryant, Jack, Roper, David I., Banzhaf, Manuel, 2023. Membrane staining and phospholipid tracking in Pseudomonas aeruginosa PAO1 using the phosphatidylcholine mimic propargyl-choline. Access Microbiology
- 'J?nior, Jos? Renato Pattaro, 'Caruso, ?caro Putinhon, 'de S?, J?ssica Mar?stica, 'Mezalira, Taniara Suelen, 'de Souza Lima, Diego, 'Pilau, Eduardo Jorge, 'Roper, David I., 'Fernandez, Maria Aparecida, 'Vicente Seixas, Flavio Augusto, 2022. 'Characterization of secondary structure and thermal stability by biophysical methods of the D-alanyl,D-alanine ligase B protein from Escherichia coli. Protein & Peptide Letters, 29 (5), pp. 448-459
- 'Dhaonoa, Gurneet K., 'Kushnir, Inbar, 'Qimron, Udi, 'Roper, David I., 'Sagona, Antonia P., 2022. 'Investigating the effect of bacteriophages on bacterial FtsZ localisation. Frontiers in Cellular and Infection Microbiology-Microbiome in Health and Disease, 12
- Ashraf, Khuram U., Nygaard, Rie, Vickery, Owen N., Erramilli, Satchal K., Herrera, Carmen M., McConville, Thomas H., Petrou, Vasileios I., Giacometti, Sabrina I., Belcher Dufrisne, Meagan, Nosol, Kamil, Zinkle, Allen P., Graham, Chris L. B., Loukeris, Michael, Kloss, Brian, Skorupinska-Tudek, Karolina, Swiezewska, Ewa, Roper, David I., Clarke, Oliver B., Uhlemann, Anne-Catrin, Kossiakof, Anthony A. et al (Select to open full list), 2022. Structural basis of lipopolysaccharide maturation by the WaaL O-antigen ligase. Nature, 604, pp. 371-376
- Dowson, Amanda J., Lloyd, Adrian J., Cuming, Andrew C., Roper, David I., Frigerio, Lorenzo, Dowson, Christopher G., 2022. Plant peptidoglycan precursor biosynthesis : conservation between moss chloroplasts and Gram-negative bacteria. Plant Physiology, 190 (1), pp. 165-179
- Tran, Wendy, Kusay, Ali S., Hawkins, Paige M. E., Cheung, Chen-Yi, Nagalingam, Gayathri, Pujari, Venugopal, Ford, Daniel J., Stoye, Alexander, Ochoa, Jessica L., Audette, Rebecca E., Hortle, Elinor, Oehlers, Stefan H., Charman, Susan A., Linington, Roger G., Rubin, Eric J., Dowson, Christopher G., Roper, David I., Crick, Dean C., Balle, Thomas, Cook, Gregory M. et al (Select to open full list), 2021. Synthetic sansanmycin analogues as potent mycobacterium tuberculosis translocase I inhibitors. Journal of Medicinal Chemistry, 64 (23), pp. 17326-17345
- Briggs, Nicholas, Bruce, Kevin E., Naskar, Souvik, Winkler, Malcolm E., Roper, David I., 2021. The pneumococcal divisome : dynamic control of streptococcus pneumoniae cell division. Frontiers in Microbiology, 12
- Graham, Chris L. B., Newman, Hector, Gillett, Francesca, Smart, Katie, Briggs, Nicholas, Banzhaf, Manuel, Roper, David I., 2021. A dynamic network of proteins facilitate cell envelope biogenesis in gram-negative bacteria. International Journal of Molecular Sciences, 22 (23)
- Aggarwal, Surya D., Lloyd, Adrian J., Yerneni, Saigopalakrishna S., Narciso, Ana Rita, Shepherd, Jennifer, Roper, David I., Dowson, Christopher G., Filipe, Sergio R, Hiller, N Luisa, 2021. A molecular link between cell wall biosynthesis, translation fidelity, and stringent response in Streptococcus pneumoniae. Proceedings of the National Academy of Sciences of the United States of America, 118 (14)
- York, Anna, Lloyd, Adrian J., del Genio, Charo I., Shearer, Jonathan, Hinxman, Karen, Fritz, Konstantin, Fülöp, Vilmos, Dowson, Christopher G., Khalid, Syma, Roper, David I., 2021. Structure-based modeling and dynamics of MurM, a Streptococcus pneumoniae penicillin resistance determinant present at the cytoplasmic membrane. Structure, 29 (7), pp. 731-742
- Cook, Jonathan P., Baverstock, Tyler, McAndrew, Martin B. L., Stansfeld, Phillip J., Roper, David I., Crow, Allister, 2020. Insights into intrinsic resistance and bacterial cell division from a structure of EnvC bound to the FtsX periplasmic domain. Proceedings of the National Academy of Sciences of the United States of America, 117 (45), pp. 28355-28365
- Bryant, Jack Alfred, Morris, Faye C., Knowles, Timothy J., Maderbocus, Riyaz, Heinz, Eva, Boelter, Gabriela, Alodaini, Dema, Colyer, Adam, Wotherspoon, Peter J., Staunton, Kara A., Jeeves, Mark, Browning, Douglas F., Sevastsyanovich, Yanina R., Wells, Timothy J., Rossiter, Amanda E., Bavro, Vassiliy N., Sridhar, Pooja, Ward, Douglas G., Chong, Zhi-Soon, Goodall, Emily CA et al (Select to open full list), 2020. Structure of dual BON-domain protein DolP identifies phospholipid binding as a new mechanism for protein localisation. eLife, 9
- Catherwood, Anita C., Lloyd, Adrian J., Tod, Julie A., Chauhan, Smita, Slade, Susan E., Walkowiak, Grzegorz P., Galley, Nicola F., Punekar, Avinash S., Smart, Katie, Rea, Dean, Evans, Neil D., Chappell, Michael J., Roper, David I., Dowson, Christopher G., 2020. Substrate and stereochemical control of peptidoglycan cross-linking by transpeptidation by Escherichia coli PBP1B. Journal of the American Chemical Society, 142 (11), pp. 5034-5048
- 'Lockey, Christine, 'Edwards, Richard J., 'Roper, David I., 'Dixon, Ann M., 2020. 'The extracellular domain of two-component system sensor kinase VanS from streptomyces coelicolor binds Vancomycin at a newly identified binding site. Scientific Reports, 10 (1)
- Kuru, Erkin, Radkov, Atanas, Meng, Xin, Egan, Alexander, Alvarez, Laura, Dowson, Amanda, Booher, Garrett, Breukink, Eefjan, Roper, David I., Cava, Felipe, Vollmer, Waldemar, Brun, Yves, VanNieuwenhze, Michael S., 2019. Mechanisms of incorporation for D-amino acid probes that target peptidoglycan biosynthesis. ACS Chemical Biology, 14 (12), pp. 2745-2756
- Teo, Alvin C. K., Lee, Sarah C., Pollock, Naomi L., Stroud, Zoe, Hall, Stephen, Thakker, Alpesh, Pitt, Andrew R., Dafforn, Timothy R., Spickett, Corinne M., Roper, David I., 2019. Analysis of SMALP co-extracted phospholipids shows distinct membrane environments for three classes of bacterial membrane protein. Scientific Reports, 9 (1)
- Pollock, Naomi, Rai, Megha, Simon, Kailene S., Hesketh, Sophie J., Teo, Alvin C. K., Parmar, Mayuriben, Sridhar, Pooja, Collins, Richard, Lee, Sarah C., Stroud, Zoe N., Bakker, Saskia, Muench, Stephen P., Barton, C. Howard, Hurlbut, Gregory, Roper, David I., Smith, Corinne J., Knowles, Timothy J., Spickett, Corinne M., East, J. Malcolm, Postis, Vincent et al (Select to open full list), 2019. SMA-PAGE : a new method to examine complexes of membrane proteins using SMALP nano-encapsulation and native gel electrophoresis. Biochimica et Biophysica Acta (BBA) - Biomembranes, 186 (8), pp. 1437-1445
- Massarweh, Ahmad, Bosco, Michael, Chantret, Isabelle, Léger, Thibaut, Jamal, Layla, Roper, David I., Dowson, Christopher G., Busca, Patricia, Bouhss, Ahmed, Gravier-Pelletier, Christine, Moore, Stuart E. H., 2019. Bacterial lipid II analogs : novel in vitro substrates for mammalian oligosaccharyl diphosphodolichol diphosphatase (DLODP) activities. Molecules, 24 (11)
- Lee, Sarah C., Collins, Richard, Lin, Yu-pin, Jamshad, Mohammed, Broughton, Claire E., Harris, Sarah A., Hanson, Benjamin S, Tognoloni, Cecilia, Parslow, Rosemary A., Terry, Ann E., Rodger, Alison, Smith, Corinne J., Edler, Karen J., Ford, Robert, Roper, David I., Dafforn, Timothy R., 2019. Nano-encapsulated escherichia coli divisome anchor ZipA, and in complex with FtsZ. Scientific Reports, 9 (1)
- Cain, Ricky, Salimraj, Ramya, Punekar, Avinash S., Bellini, Dom, Fishwick, Colin W. G., Czaplewski, Lloyd, Scott, David J., Harris, Gemma, Dowson, Christopher G., Lloyd, Adrian J., Roper, David I., 2019. Structure-guided enhancement of selectivity of chemical probe inhibitors targeting bacterial seryl-tRNA synthetase. Journal of Medicinal Chemistry, 62 (21), pp. 9703-9717
- Simpson, Daniel H., Hapeshi, Alexia, Rogers, Nicola J., Brabec, Viktor, Clarkson, Guy J., Fox, David J., Hrabina, Ondrej, Kay, Gemma L., King, Andrew, Malina, Jaroslav, Millard, Andrew D., Moat, John, Roper, David I., Song, Hualong, Waterfield, Nicholas R., Scott, Peter, 2019. Metallohelices that kill Gram-negative pathogens using intracellular antimicrobial peptide pathways. Chemical Science, 10, pp. 9708-9720
- Hrast, Martina, Jukic, Marko, Patin, Delphine, Tod, Julie, Dowson, Christopher G., Roper, David I., Barreteau, Hélène, Gobec, Stanislav, 2018. In silico identification, synthesis and biological evaluation of novel tetrazole inhibitors of MurB. Chemical Biology & Drug Design, 91 (6), pp. 1101-1112
- Punekar, Avinash S., Samsudin, Firdaus, Lloyd, Adrian J., Dowson, Christopher G., Scott, David J., Khalid, Syma, Roper, David I., 2018. The role of the jaw subdomain of peptidoglycan glycosyltransferases for lipid II polymerization. The Cell Surface, 2, pp. 54-66
- Ábrányi-Balogh, Péter, Petri, László, Imre, Tímea, Szijj, Péter, Scarpino, Andrea, Hrast, Martina, Mitrovic, Ana, Fonovic, Ur?a Pecar, Németh, Krisztina, Barreteau, Hélène, Roper, David I., Horváti, Kata, Ferenczy, György G, Kos, Janko, Ila?, Janez, Gobec, Stanislav, Keseru, György M, 2018. A road map for prioritizing warheads for cysteine targeting covalent inhibitors. European Journal of Medicinal Chemistry, 160, pp. 94-107
- Ábrányi-Balogh, Péter, Petri, László, Imre, Tímea, Szijj, Péter, Scarpino, Andrea, Hrast, Martina, Mitrovic, Ana, Fonovic, Ur?a Pecar, Németh, Krisztina, Barreteau, Hélène, Roper, David I., Horváti, Kata, Ferenczy, György G., Kos, Janko, Ila?, Janez, Gobec, Stanislav, Keseru, György M., 2018. A road map for prioritizing warheads for cysteine targeting covalent inhibitors. European Journal of Medicinal Chemistry, 160, pp. 94-107
- Meyer, Karen, Addy, Christine, Akashi, Satoko, Roper, David I., Tame, Jeremy R. H., 2018. The crystal structure and oligomeric form of Escherichia coli L,D-carboxypeptidase A. Biochemical and Biophysical Research Communications, 499 (3), pp. 594-599
- Ábrányi-Balogh, Péter, Petri, László, Imre, Tímea, Szijj, Péter, Scarpino, Andrea, Hrast, Martina, Mitrovic, Ana, Fonovic, Ur?a Pecar, Németh, Krisztina, Barreteau, Hélène, Roper, David I., Horváti, Kata, Ferenczy, György G, Kos, Janko, Ila?, Janez, Gobec, Stanislav, Keseru, György M, 2018. A road map for prioritizing warheads for cysteine targeting covalent inhibitors.. European Journal of Medicinal Chemistry, 160, pp. 94-107
- Vajs, Jure, Proud, Conor, Brozovic, Anamaria, Gazvoda, Martin, Lloyd, Adrian J., Roper, David I., Osmak, Maja, Ko?mrlj, Janez, Dowson, Christopher G., 2017. Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis. European Journal of Medicinal Chemistry, 127, pp. 223-234
- Sychantha, David, Jones, Carys S., Little, Dustin J., Moynihan, Patrick J., Robinson, Howard, Galley, Nicola F., Roper, David I., Dowson, Christopher G., Howell, P. Lynne, Clarke, Anthony J., 2017. In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA). PLOS Pathogens, 13 (10)
- Batson, Sarah, de Chiara, Cesira, Majce, Vita, Lloyd, Adrian J., Gobec, Stanislav, Rea, Dean, Fülöp, Vilmos, Thoroughgood, Christopher W., Simmons, Katie J., Dowson, Christopher G., Fishwick, Colin W. G., de Carvalho, Luiz Pedro S., Roper, David I., 2017. Inhibition of D-Ala : D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine. Nature Communications, 8 (1)
- Tran, Anh T., Watson, Emma E., Pujari, Venugopal, Conroy, Trent, Dowman, Luke J., Giltrap, Andrew M., Pang, Angel, Wong, Weng Ruh, Linington, Roger G., Mahapatra, Sebabrata, Saunders, Jessica, Charman, Susan A., West, Nicholas P., Bugg, Tim, Tod, Julie, Dowson, Christopher G., Roper, David I., Crick, Dean C., Britton, Warwick J., Payne, Richard J., 2017. Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis. Nature Communications, 8
- Calvez, Philippe, Breukink, Eefjan, Roper, David I., Dib, Mélanie, Contreras-Martel, Carlos, Zapun, André, 2017. Substitutions in PBP2b from ?-lactam resistant Streptococcus pneumoniae have different effects on enzymatic activity and drug reactivity. Journal of Biological Chemistry, 292 (7), pp. 2854-2865
- Tran, Anh T., Watson, Emma E., Pujari, Venugopal, Conroy, Trent, Dowman, Luke J., Giltrap, Andrew M., Pang, Angel, Wong, Weng-Ruh, Linington, Roger G., Saunders, Jessica, Charman, Susan A., West, Nicholas P., Bugg, Tim, Tod, Julie, Dowson, Christopher G., Roper, David I., Crick, Dean C., Britton, Warwick J., Payne, Richard J., 2017. Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis.. Nature Communications, 8
- Kaner, Rebecca A., Allison, Simon A., Faulkner, Alan D., Simpson, Daniel H., Waterfield, Nicholas R., Phillips, Roger M., Roper, David I., Shepherd, Samantha L., Scott, Peter, 2016. Anticancer metallohelices : nanomolar potency and high selectivity. Chemical Science, 7 (2), pp. 951-958
- Usha, Veeraraghavan, Lloyd, Adrian J., Roper, David I., Dowson, Christopher G., Kozlov, Guennadi, Gehring, Kalle, Chauhan, Smita, Imam, Hasan T., Blindauer, Claudia A., Besra, Gurdyal S., 2016. Reconstruction of diaminopimelic acid biosynthesis allows characterisation of Mycobacterium tuberculosis N-succinyl-L,L-diaminopimelic acid desuccinylase. Scientific Reports, 6
- Broughton, Claire E., Berg, Hugo van den, Wemyss, Alan M., Roper, David I., Rodger, Alison, 2016. Beyond the discovery void : new targets for antibacterial compounds. Science Progress, 99 (2), pp. 153-182
- Dow, Claire E., Berg, Hugo van den, Roper, David I., Rodger, Alison, 2015. Biological insights from a simulation model of the critical FtsZ accumulation required for prokaryotic cell division. Biochemistry, 54 (24), pp. 3803-3813
- Broughton, Claire E., Roper, David I., Berg, Hugo van den, Rodger, Alison, 2015. Bacterial cell division : experimental and theoretical approaches to the divisome. Science Progress, 98 (4), pp. 313-345
- Zuegg, Johannes, Muldoon, Craig, Adamson, George, McKeveney, Declan, Thanh, Giang Le, Premraj, Rajaratnam, Becker, Bernd, Cheng, Mu, Elliott, Alysha G., Huang, Johnny X., Butler, Mark S., Bajaj, Megha, Seifert, Joachim, Singh, Latika, Galley, Nicola F., Roper, David I., Lloyd, Adrian J., Dowson, Christopher G., Cheng, Ting-Jen, Cheng, Wei-Chieh et al (Select to open full list), 2015. Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity. Nature Communications, 6, pp. 1-11
- Li, Qiong, Cheng, Wang, Morlot, Cécile, Bai, Xiao-Hui, Jiang, Yong-Liang, Wang, Wenjia, Roper, David I., Vernet, Thierry, Dong, Yu-Hui, Chen, Yuxing, Zhou, Cong-Zhao, 2015. Full-length structure of the major autolysin LytA. Acta Crystallographica Section D Biological Crystallography, 71 (6), pp. 1373-1381
- Teo, Alvin, Roper, David I., 2015. Core steps of membrane-bound peptidoglycan biosynthesis : recent advances, insight and opportunities. Antibiotics, 4 (4), pp. 495-520
- Rodolis, Maria T., Mihalyi, Agnes, O'Reilly, Amy M., Slikas, Justinas, Roper, David I., Hancock, Robert E. W., Bugg, Tim, 2014. Identification of a novel inhibition site in Translocase MraY based upon the site of interaction with Lysis Protein E from Bacteriophage ?X174. Chembiochem, 15 (9), pp. 1300-1308
- Galley, Nicola F., O'Reilly, Amy M., Roper, David I., 2014. Prospects for novel inhibitors of peptidoglycan transglycosylase. Bioorganic Chemistry, 55 (100), pp. 16-26
- Braddick, Darren, Sandhu, Sandeep, Roper, David I., Chappell, M. J. (Michael J.), Bugg, Tim, 2014. Observation of the time-course for peptidoglycan lipid intermediate II polymerization by Staphylococcus aureus monofunctional transglycosylase. Microbiology, 160 (Part 8), pp. 1628-1636
- Faulkner, Alan D., Kaner, Rebecca A., Abdallah, Qasem M. A., Clarkson, Guy J., Fox, David J., Gurnani, Pratik, Howson, Suzanne E., Phillips, Roger M., Roper, David I., Simpson, Daniel H., Scott, Peter, 2014. Asymmetric triplex metallohelices with high and selective activity against cancer cells. Nature Chemistry, 6 (9), pp. 797-803
- Paulin, Sarah, Jamshad, Mohammed, Dafforn, Tim, Garcia-Lara, Jorge, Foster, Simon J., Galley, Nicola F., Roper, David I., Rosado, Helena, Taylor, Peter W., 2014. Surfactant-free purification of membrane protein complexes from bacteria : application to the staphylococcal penicillin-binding protein complex PBP2/PBP2a. Nanotechnology, 25 (28)
- Meigh, Louise, Greenhalgh, Sophie A., Rodgers, Thomas L., Cann, Martin J., Roper, David I., Dale, Nicholas, 2013. CO2 directly modulates connexin 26 by formation of carbamate bridges between subunits. eLife, 2
- Lloyd, Adrian J., Potter, Nicola J., Fishwick, Colin W. G., Roper, David I., Dowson, Christopher G., 2013. Adenosine tetraphosphoadenosine drives a continuous ATP-release assay for aminoacyl-tRNA synthetases and other adenylate-forming enzymes. ACS Chemical Biology, 8 (10), pp. 2157-2163
- Pacheco-Gómez, Raúl, Cheng, Xi, Hicks, Matthew R., Smith, Corinne J., Roper, David I., Addinall, Stephen G., Rodger, Alison, Dafforn, Tim, 2013. Tetramerization of ZapA is required for FtsZ bundling. Biochemical Journal, 449 (3), pp. 795-802
- Dow, Claire E., Rodger, Alison, Roper, David I., Berg, Hugo van den, 2013. A model of membrane contraction predicting initiation and completion of bacterial cell division. Integrative Biology, pp. 778-795
- Lloyd, Adrian J., Potter, Nicola J., Fishwick, Colin W. G., Roper, David I., Dowson, Christopher G., 2013. Adenosine Tetraphosphoadenosine drives a continuous ATP-release assay for Aminoacyl-tRNA synthetases and other Adenylate-forming enzymes. ACS Chemical Biology, 8 (10), pp. 2157-2163
- Majce, Vita, Ruane, Karen M., Gobec, Stanislav, Roper, David I., 2013. Crystallization and preliminary X-ray analysis of a UDP-MurNAc-tripeptideD-alanyl-D-alanine-adding enzyme (PaMurF) from Pseudomonas aeruginosa. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 69 (number 5), pp. 503-505
- Zapun, André, Philippe, Jules, Abrahams, Katherine A., Signor, Luca, Roper, David I., Breukink, Eefjan, Vernet, Thierry, 2013. In vitro reconstitution of peptidoglycan assembly from the gram-positive pathogen streptococcus pneumoniae. ACS Chemical Biology, 8 (12), pp. 2688-2696
- Valegård, Karin, Iqbal, Aman, Kershaw, Nadia J., Ivison, David, Généreux, Catherine, Dubus, Alain, Blikstad, Cecilia, Demetriades, Marina, Hopkinson, Richard J., Lloyd, Adrian J., Roper, David I., Schofield, Christopher J., Andersson, Inger, McDonough, Michael A., 2013. Structural and mechanistic studies of theorf12 gene product from the clavulanic acid biosynthesis pathway. Acta Crystallographica Section D Biological Crystallography, 69 (8), pp. 1567-1579
- Ruane, Karen M., Lloyd, Adrian J., Fülöp, Vilmos, Dowson, Christopher G., Barreteau, Hélène, Boniface, Audrey, Dementin, Sébastien, Blanot, Didier, Mengin-Lecreulx, Dominique, Gobec, Stanislav, Dessen, Andréa, Roper, David I., 2013. Specificity determinants for lysine incorporation in staphylococcus aureus peptidoglycan as revealed by the structure of a MurE enzyme ternary complex. Journal of Biological Chemistry, 288 (46)
- Turner, Daniel J., Portman, Ian, Dafforn, Tim, Rodger, Alison, Roper, David I., Smith, Corinne J., Turner, Matthew S., 2012. The Mechanics of FtsZ fibers. Biophysical Journal, Vol.102 (No.4), pp. 731-738
- Yoshida, Hisashi, Kawai, Fumihiro, Obayashi, Eiji, Akashi, Satoko, Roper, David I., Tame, Jeremy R.H., Park, Sam-Yong, 2012. Crystal structures of penicillin-binding protein 3 (PBP3) from methicillin-resistant staphylococcus aureus in the apo and cefotaxime-bound forms. Journal of Molecular Biology, 423 (3), pp. 351-364
- Hattersley, John G., Pérez-Velázquez, J., Chappell, M. J. (Michael J.), Bearup, Daniel James, Roper, David I., Dowson, Christopher G., Bugg, Tim, Evans, Neil D., 2011. Indistinguishability and identifiability of kinetic models for the MurC reaction in peptidoglycan biosynthesis. Computer Methods and Programs in Biomedicine, Vol.104 (No.2), pp. 70-80
- Pacheco-Gómez, Raúl, Roper, David I., Dafforn, Tim, Rodger, Alison, 2011. The pH dependence of polymerization and bundling by the essential bacterial cytoskeltal protein FtsZ. PLoS One, Vol.6 (No.6)
- Bugg, Tim, Braddick, Darren, Dowson, Christopher G., Roper, David I., 2011. Bacterial cell wall assembly : still an attractive antibacterial target. Trends in Biotechnology, Vol.29 (No.4), pp. 167-173
- Kawai, Fumihiro, Clarke, Thomas B., Roper, David I., Han, Gab-Jo, Hwang, Kwang Yeon, Unzai, Satoru, Obayashi, Eiji, Park, Sam-Yong, Tame, Jeremy R. H., 2010. Crystal structures of penicillin-binding proteins 4 and 5 from Haemophilus influenzae. Journal of Molecular Biology, Vol.396 (No.3), pp. 634-645
- Batson, Sarah, Rea, Dean, Fülöp, Vilmos, Roper, David I., 2010. Crystallization and preliminary X-ray analysis of a D-alanyl-D-alanine ligase (EcDdlB) from Escherichia coli. Journal of Experimental Psychology: Human Perception and Performance, Vol.66 (No.4), pp. 405-408
- Clarke, Thomas B., Kawai, Fumihiro, Park, Sam-Yong, Tame, Jeremy R. H., Dowson, Christopher G., Roper, David I., 2009. Mutational analysis of the substrate specificity of Escherichia coli penicillin binding protein 4. Biochemistry, Vol.48 (No.12), pp. 2675-2683
- Sova, Matej, Cadez, Gasper, Turk, Samo, Majce, Vita, Polanc, Slovenko, Batson, Sarah, Lloyd, Adrian, Roper, David I., Fishwick, Colin W. G., Gobec, Stanislav, 2009. Design and synthesis of new hydroxyethylamines as inhibitors of D-alanyl-D-lactate ligase (VanA) and D-alanyl-D-alanine ligase (DdlB). Bioorganic & Medicinal Chemistry Letters, Vol.19 (No.5), pp. 1376-1379
- Cressina, Elena, Lloyd, Adrian J., De Pascale, Gianfranco, Mok, B. James, Caddick, Stephen, Roper, David I., Dowson, Christopher G., Bugg, Tim, 2009. Inhibition of tRNA-dependent ligase MurM from Streptococcus pneumoniae by phosphonate and sulfonamide inhibitors. Bioorganic & Medicinal Chemistry, Vol.17 (No.9), pp. 3443-3455
- Paradis-Bleau, Catherine, Lloyd, Adrian, Sanschagrin, Francois, Maaroufi, Halim, Clarke, Thomas B., Blewett, Ann, Dowson, Christopher G., Roper, David I., Bugg, Tim, Levesque, Roger C., 2009. Pseudomonas aeruginosa MurE amide ligase : enzyme kinetics and peptide inhibitor. Biochemical Journal, Vol.421 (No. 2), pp. 263-272
- Usha, Veeraraghavan, Dover, Lynn G., Roper, David I., Fuetterer, Klaus, Besra, Gurdyal S., 2009. Structure of the diaminopimelate epimerase DapF from Mycobacterium tuberculosis. Acta Crystallographica Section D: Biological Crystallography, Vol.65 (No.4), pp. 383-387
- Lloyd, Adrian J., Gilbey, Andrea M., Blewett, Anne M., De Pascale, Gianfranco, El Zoeiby, Ahmed, Levesque, Roger C., Catherwood, Anita C., Tomasz, Alexander, Bugg, Tim, Roper, David I., Dowson, Christopher G., 2008. Characterization of tRNA-dependent peptide bond formation by MurM in the synthesis of Streptococcus pneumoniae peptidoglycan. Journal of Biological Chemistry, Vol.283 (No.10), pp. 6402-6417
- Usha, Veeraraghavan, Dover, Lynn G., Roper, David I., Besra, Gurdyal S., 2008. Characterization of Mycobacterium tuberculosis diaminopimelic acid epimerase: paired cysteine residues are crucial for racemization. FEMS Microbiology Letters, Vol.280 (No.1), pp. 57-63
- Rea, Dean, Hovington, Rebecca, Rakus, John F., Gerlt, John A., Fülöp, Vilmos, Bugg, Tim, Roper, David I., 2008. Crystal structure and functional assignment of YfaU, a metal ion dependent class II aldolase from Escherichia coli K12. Biochemistry, Vol.47 (No.38), pp. 9955-9965
- De Pascale, Gianfranco, Lloyd, Adrian J., Schouten, James A., Gilbey, Andrea M., Roper, David I., Dowson, Christopher G., Bugg, Tim, 2008. Kinetic characterization of lipid II-Ala:Alanyl-tRNA ligase (MurN) from streptococcus pneumoniae using semisynthetic aminoacyl-lipid II substrates. Journal of Biological Chemistry, Vol.283 (No.50), pp. 34571-34579
- Alderwick, Luke J., Dover, Lynn G., Veerapen, Natacha, Gurcha, Sudagar S., Kremer, Laurent, Roper, David I., Pathak, Ashish K., Reynolds, Robert C., Besra, Gurdyal S., 2008. Expression, purification and characterisation of soluble GlfT and the identification of a novel galactofuranosyltransferase Rv3782 involved in priming GlfT-mediated galactan polymerisation in Mycobacterium tuberculosis. Protein Expression and Purification, Vol.58 (No.2), pp. 332-341
- Izumi, Atsushi, Rea, Dean, Adachi, Tomoko, Unzai, Satoru, Park, Sam-Yong, Roper, David I., Tame, Jeremy R. H., 2007. Structure and mechanism of HpcG, a hydratase in the homoprotocatechuate degradation pathway of Escherichia coli. Journal of Molecular Biology, Vol.370 (No.5), pp. 899-911
- Rea, Dean, Fülöp, Vilmos, Bugg, Tim, Roper, David I., 2007. Structure and mechanism of HpcH : a metal ion dependent class II aldolase from the homoprotocatechuate degradation pathway of Escherichia coli. Journal of Molecular Biology, Vol.373 (No.4), pp. 866-876
- Lee, Sarah C., Stoilova-Mcphie, Svetla, Baxter, Laura, Fülöp, Vilmos, Henderson, Janey, Rodger, Alison, Roper, David I., Scott, David J., Smith, Corinne J., Morgan, J. Alun W., 2007. Structural characterisation of the insecticidal toxin XptA1, reveals a 1.15 MDa tetramer with a cage-like structure. Journal of Molecular Biology, Vol.366 (No.5), pp. 1558-1568
- Lysenko, Elena S., Clarke, Thomas B., Shchepetov, Mikhail, Ratner, Adam J., Roper, David I., Dowson, Christopher G., Weiser, Jeffrey N., 2007. Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing. PLoS Pathogens, Vol.3 (No.8), pp. 1073-1081
- Cressina, Elena, Lloyd, Adrian J., De Pascale, Gianfranco, Roper, David I., Dowson, Christopher G., Bugg, Tim, 2007. Adenosine phosphonate inhibitors of lipid II: Alanyl tRNA ligase MurM from Streptococcus pneumoniae. Bioorganic & Medicinal Chemistry Letters, Vol.17 (No.16), pp. 4654-4656
- Lysenko, Elena S., Clarke, Thomas B., Shchepetov, Mikhail, Ratner, Adam J., Roper, David I., Dowson, Christopher G., Weiser, Jeffrey N., 2007. Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing. PL o S Pathogens, Vol.3 (No.8), pp. 1073-1081
- Tötemeyer, Sabine, Sheppard, Mark, Lloyd, Adrian, Roper, David I., Dowson, Christopher G., Underhill, David, Murray, Peter, Maskell, Duncan, Bryant, Clare, 2006. IFN-gamma enhances production of nitric oxide from macrophages via a mechanism that depends on nucleotide oligomerization domain-2. Journal of Immunology, Vol.176 (No.8), pp. 4804-4810
- Adachi, Tomoko, Izumi, Atsushi, Rea, Dean, Park, Sam-Yong, Tame, Jeremy R. H., Roper, David I., 2006. Expression, purification and crystallization of 2-oxo-hept-4-ene-1,7-dioate hydratase (HpcG) from Escherichia coli C. Acta Crystallographica Section F-Structural Biology And Crystallization Communicati, 62 (Part 10), pp. 1010-1012
- Usha, Veeraraghavan, Dover, Lynn G., Roper, David I., Lloyd, Adrian J., Besra, Gurdyal S., 2006. Use of a codon alteration strategy in a novel approach to cloning the Mycobacterium tuberculosis diaminopimelic acid epimerase. FEMS Microbiology Letters, 262 (1), pp. 39-47
- Kishida, H., Unzai, Satoru, Roper, David I., Lloyd, A, Park, S.Y., Tame, Jeremy R. H., 2006. Crystal structure of penicillin binding protein 4 (dacB) from Escherichia coli, both in the native form and covalently linked to various antibiotics. Biochemistry, Vol.45 (No.3), pp. 783-792
- 'Schouten, James A., 'Bagga, Sangeev, 'Lloyd, Adrian J., 'De Pascale, Gianfranco, 'Dowson, Christopher G., 'Roper, David I., 'Bugg, Timothy D. H., 2006. 'Fluorescent reagents for in vitro studies of lipid-linked steps of bacterial peptidoglycan biosynthesis: derivatives of UDPMurNAc-pentapeptide containing d-cysteine at position 4 or 5.. Molecular BioSystems, 2 (10), pp. 484-491
- 'Bugg, Timothy D. H., 'Lloyd, Adrian J., 'Roper, David I., 2006. 'Phospho-MurNAc-pentapeptide translocase (MraY) as a target for antibacterial agents and antibacterial proteins. Infectious Disorders - Drug Targets, 6 (2), pp. 85-106
- 'Besong, Gilbert E., 'Bostock, Julieanne M., 'Stubbings, Will, 'Chopra, Ian, 'Roper, David I., 'Lloyd, Adrian J., 'Fishwick, Colin W. G., 'Johnson, A. Peter, 2005. 'A de novo designed inhibitor of D-Ala-D-Ala ligase from E. coli. Angewandte Chemie (International Edition), 44 (39), pp. 6403-6406
- Dhanoa, Gurneet, Roper, David I., Sagona, Antonia P., 2022. Investigation of the localisation of FtsZ in pathogenic E. coli upon bacteriophage addition in a human cell model as a biomarker for antibacterial agents. Access Microbiology, Microbiology Society
- 'Lockey, Christine, 'Edwards, Richard J., 'Roper, David I., 'Dixon, Ann M., 2020. 'Data for The extracellular domain of two-component system sensor kinase VanS from streptomyces coelicolor binds Vancomycin at a newly identified binding site.. University of Warwick, Department of Chemistry
- Kaner, Rebecca A., Allison, Simon A., Faulkner, Alan D., Simpson, Daniel H., Waterfield, Nicholas R., Phillips, Roger M., Roper, David I., Shepherd, Samantha L., Scott, Peter, 2015. Data for Anticancer metallohelices : nanomolar potency and high selectivity. University of Warwick. Science. Chemistry. Scott Group
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| Title | Funder | Award start | Award end |
|---|---|---|---|
| Cell Wall Formation in Rod Shaped Bacteria - BBSRC sLoLa Full Stage - February 2023 | BBSRC | 01 Mar 2024 | 31 Jan 2029 |
| FtsEX-PcsB: A protein complex required for cell division in S. pneumoniae - MRC I&I Responsive Mode - September 2023 | Medical Research Council (MRC) | 01 Jul 2024 | 30 Jun 2027 |
| Collaborative visit to India | Academy of Medical Sciences | 04 Nov 2018 | 01 Mar 2023 |
| Maintaining cell wall integrity in Gram-Negative Bacteria (Chris Graham) | UK Research and Innovation | 01 Apr 2020 | 30 Sep 2022 |
| Antibiotic Breaker- The outer membrane and peptidoglycan link as a new antibiotic vulnerability | Antibiotic Research UK | 02 Sep 2021 | 01 Sep 2022 |
| MRC UK China Hubs | MRC | 01 Jan 2019 | 31 Mar 2022 |
| Mechanistic understanding of cell wall biosynthesis to combat antimicrobial resistance: Cell Wall AMR | MRC | 01 Jul 2015 | 28 Aug 2021 |
| 19 Alert mid-range Equipment Initiative: equipment to upgrade the 600 NMR console at the NMR facility. | BBSRC | 01 Nov 2020 | 31 Mar 2021 |
| Understanding how bacteria divide: a route to new antibiotics? (Mr Souvik Naskar) | Medical and Life Sciences Research Fund | 01 Aug 2019 | 31 Dec 2020 |
| BBSRC FTMA Investigating the potential to exploit the mechanism of by which tRNA-dependent amino acid synthetases activate cognate and non-cognate amino acids as a strategy for future antibiotic development (Ricky Cain) | BBSRC | 01 Aug 2018 | 31 Jul 2019 |
| Accelerate CHNUK AMR discovery: Establishing and exploiting a joint China/UK platform to enable high throughput fragment based inhibitor discovery | MRC | 01 Jul 2016 | 30 Jun 2019 |
| 17 Alert bid led by Nottingham: A new multi-wavelength analytical ultracentrifuge for the study of biomeolcular interactions | BBSRC | 01 May 2018 | 30 Apr 2019 |
| 5th Midlands Molecular Microbiology Meeting | Company of Biologists, The | 03 Sep 2018 | 02 Oct 2018 |
| Multi-Targetting of tRNA synthetases: A paradigm shift in combating AMR | MRC | 01 Mar 2015 | 30 Nov 2017 |
| Molecular Dissection of PASTA domains from Enterococci (Researcher Mobility Grant for Christopher Thoroughgood) | Royal Society of Chemistry | 09 Mar 2017 | 08 Jun 2017 |
| Centre for integrative theoretical and experimental analytical science for application to bacterial cell division and Quality by Design (CAS-IDP) | European Commission | 01 Mar 2013 | 28 Feb 2017 |
| Team CanUK: Novel antibacterial targets, assays, probes and opportunities in bacterial cell wall biogenesis | MRC | 01 Jan 2012 | 31 Dec 2015 |
| BBSRC Link with Astra Zeneca:Reagents and assays to exploit the final steps of peptidoglycan construction | BBSRC | 01 Aug 2013 | 31 Jul 2015 |
| The biochemical characterisation of pivotal enzymes involved in mycobacterial peptidoglycan biosynthesis Birmingham-Warwick PG grant | MRC | 01 May 2011 | 30 Apr 2014 |
| (led by UCL) BBSRC project Disruption of cytoplasmic membrane-associated functions in staphylococcus aureus by epicatechin gallate led by School of Pharmacy (with Sheffield and Birmingham) | BBSRC | 04 Apr 2011 | 03 Apr 2014 |
| Subproject for Institution # 33323 - RCHAR3009 - A new Raman instrument for polarized spectroscopy of biomacromolecular systems | EPSRC | 01 Sep 2012 | 28 Feb 2014 |
| A new Raman instrument for polarized spectroscopy of biomacromolecular systems | EPSRC | 01 Sep 2012 | 28 Feb 2014 |
| Research Agreement :Investigation into bacterial metabolism - the biochemistry of cytoplasmic synthesis of peptidoglycan precursors entiteld Impact of ligase/MreB association on inhibitor discovery. | Basilea Pharmaceutica International Ltd | 01 Aug 2013 | 31 Jan 2014 |
| Unesco- loreal Visiting Fellowship for Vita Majce | UNESCO | 01 May 2012 | 30 Apr 2013 |
| UKCan - BACWAN | MRC | 01 Aug 2009 | 30 Apr 2010 |
| UK BACWAN 2 | University of Sheffield | 01 May 2008 | 30 Apr 2010 |
| Structure and Biology of Membrane Proteins | Wellcome Trust | 01 Jan 2005 | 31 Dec 2009 |
| MAR Imaging plate x ray data collection system | Wellcome Trust | 01 Sep 2003 | 31 Aug 2008 |
| UK - BaCWAN: UK-Bacterial Cell Wall Assembly Network | MRC | 01 Apr 2006 | 31 Mar 2008 |
| Exploration and Exploitation of the Enzymology of PBP Driven Peptidoglycan Biosynthesis to Discover Novel Non-beta Lactam Antibiotics | MRC | 01 Mar 2005 | 29 Feb 2008 |
| Towards a complete structure-function description of an aromatic degradative pathway | BBSRC | 01 Feb 2005 | 31 Jan 2008 |
| Molecular Physiology and structural analysis of the innate immune system triggered by bacterial cell wall components | British Pharmacological Society | 01 Oct 2004 | 30 Sep 2007 |
| Structure, Stability & Molecular Interactions In Biological Systems | BBSRC | 01 Sep 2005 | 31 May 2006 |
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